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  • Showing 1-15 of 15 Results
2014
5-hydroxymethylcytosine is not present in appreciable quantities in Arabidopsis DNA.Erdmann, RM, Souza AL, Clish CB, and Gehring M. G3 (Bethesda, Md.), 2014/11/06, Volume 5, Issue 1, p.1-8, (2014) Read More / View Supplemental Materials
Abstract
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.Roberts, LD, Boström P., O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A., Lee YK, Palma MJ, Calhoun S., Georgiadi A., Chen MH, Ramachandran VS, Larson MG, Bouchard C., Rankinen T., Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, et al. Cell metabolism, 2014/01/07, Volume 19, Issue 1, p.96-108, (2014) Read More / View Supplemental Materials
Abstract
2013
Reproducibility of metabolomic profiles among men and women in 2 large cohort studies.Townsend, MK, Clish CB, Kraft P., Wu C., Souza AL, Deik AA, Tworoger SS, and Wolpin BM Clinical chemistry, 2013/11/01, Volume 59, Issue 11, p.1657-67, (2013) Read More / View Supplemental Materials
Abstract
2-Aminoadipic acid is a biomarker for diabetes risk.Wang, TJ, Ngo D., Psychogios N., Dejam A., Larson MG, Vasan RS, Ghorbani A., O'Sullivan J., Cheng S., Rhee EP, Sinha S., McCabe E., Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M., Pierce KA, Souza AL, Yu Y., et al. The Journal of clinical investigation, 2013/10/01, Volume 123, Issue 10, p.4309-17, (2013) Read More / View Supplemental Materials
Abstract
A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort.Rhee, EP, Ho JE, Chen MH, Shen D., Cheng S., Larson MG, Ghorbani A., Shi X., Helenius IT, O'Donnell CJ, Souza AL, Deik A., Pierce KA, Bullock K., Walford GA, Vasan RS, Florez JC, Clish C., Yeh JR, Wang TJ, et al. Cell metabolism, 2013/07/02, Volume 18, Issue 1, p.130-43, (2013) Read More / View Supplemental Materials
Abstract
A combined epidemiologic and metabolomic approach improves CKD prediction.Rhee, EP, Clish CB, Ghorbani A., Larson MG, Elmariah S., McCabe E., Yang Q., Cheng S., Pierce K., Deik A., Souza AL, Farrell L., Domos C., Yeh RW, Palacios I., Rosenfield K., Vasan RS, Florez JC, Wang TJ, Fox CS, et al. Journal of the American Society of Nephrology : JASN, 2013/07/01, Volume 24, Issue 8, p.1330-8, (2013) Read More / View Supplemental Materials
Abstract
SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism.Jeong, SM, Xiao C., Finley LW, Lahusen T., Souza AL, Pierce K., Li YH, Wang X., Laurent G., German NJ, Xu X., Li C., Wang RH, Lee J., Csibi A., Cerione R., Blenis J., Clish CB, Kimmelman A., Deng CX, et al. Cancer cell, 2013/04/15, Volume 23, Issue 4, p.450-63, (2013) Read More / View Supplemental Materials
Abstract
2012
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.Kalaitzidis, D., Sykes SM, Wang Z., Punt N., Tang Y., Ragu C., Sinha AU, Lane SW, Souza AL, Clish CB, Anastasiou D., Gilliland DG, Scadden DT, Guertin DA, and Armstrong SA Cell stem cell, 2012/09/07, Volume 11, Issue 3, p.429-39, (2012) Read More / View Supplemental Materials
Abstract
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.Jain, M., Nilsson R., Sharma S., Madhusudhan N., Kitami T., Souza AL, Kafri R., Kirschner MW, Clish CB, and Mootha VK Science (New York, N.Y.), 2012/05/25, Volume 336, Issue 6084, p.1040-4, (2012) Read More / View Supplemental Materials
Abstract
Metabolite profiling identifies pathways associated with metabolic risk in humans.Cheng, S., Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D., Palma MJ, Roberts LD, Dejam A., Souza AL, Deik AA, Magnusson M., Fox CS, O'Donnell CJ, Vasan RS, Melander O., Clish CB, Gerszten RE, and Wang TJ Circulation, 2012/05/08, Volume 125, Issue 18, p.2222-31, (2012) Read More / View Supplemental Materials
Abstract
Targeted metabolomics.Roberts, LD, Souza AL, Gerszten RE, and Clish CB Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.], 2012/04/01, Volume Chapter 30, p.Unit 30.2.1-24, (2012) Read More / View Supplemental Materials
Abstract
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.Leoni, V., Strittmatter L., Zorzi G., Zibordi F., Dusi S., Garavaglia B., Venco P., Caccia C., Souza AL, Deik A., Clish CB, Rimoldi M., Ciusani E., Bertini E., Nardocci N., Mootha VK, and Tiranti V. Molecular genetics and metabolism, 2012/03/01, Volume 105, Issue 3, p.463-71, (2012) Read More / View Supplemental Materials
Abstract
2011
A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1alpha stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like.Kelly, TJ, Souza AL, Clish CB, and Puigserver P. Molecular and cellular biology, 2011/07/01, Volume 31, Issue 13, p.2696-706, (2011) Read More / View Supplemental Materials
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2010
Activation of a metabolic gene regulatory network downstream of mTOR complex 1.Düvel, K., Yecies JL, Menon S., Raman P., Lipovsky AI, Souza AL, Triantafellow E., Ma Q., Gorski R., Cleaver S., Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, and Manning BD Molecular cell, 2010/07/30, Volume 39, Issue 2, p.171-83, (2010) Read More / View Supplemental Materials
Abstract
A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells.Shaham, O., Slate NG, Goldberger O., Xu Q., Ramanathan A., Souza AL, Clish CB, Sims KB, and Mootha VK Proceedings of the National Academy of Sciences of the United States of America, 2010/01/26, Volume 107, Issue 4, p.1571-5, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-15 of 15 Results