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  • Showing 1-18 of 18 Results
2014
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics.Lundby, A., Rossin EJ, Steffensen AB, Acha MR, Newton-Cheh C., Pfeufer A., Lynch SN, The QT Interval International GWAS Consortium(QT-IGC), Olesen SP, Brunak S., Ellinor PT, Jukema JW, Trompet S., Ford I., Macfarlane PW, Krijthe BP, Hofman A., Uitterlinden AG, Stricker BH, Nathoe HM, et al. Nature methods, 2014/06/22, (2014) Read More / View Supplemental Materials
Abstract
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.Arking, DE, Pulit SL, Crotti L., van der Harst P., Munroe PB, Koopmann TT, Sotoodehnia N., Rossin EJ, Morley M., Wang X., Johnson AD, Lundby A., Gudbjartsson DF, Noseworthy PA, Eijgelsheim M., Bradford Y., Tarasov KV, Dörr M., Müller-Nurasyid M., Lahtinen AM, et al. Nature genetics, 2014/06/22, (2014) Read More / View Supplemental Materials
Abstract
Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci.Tragante, V., Barnes MR, Ganesh SK, Lanktree MB, Guo W., Franceschini N., Smith EN, Johnson T., Holmes MV, Padmanabhan S., Karczewski KJ, Almoguera B., Barnard J., Baumert J., Chang YP, Elbers CC, Farrall M., Fischer ME, Gaunt TR, Gho JM, et al. American journal of human genetics, 2014/02/19, (2014) Read More / View Supplemental Materials
Abstract
2013
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.Flannick, J., Beer NL, Bick AG, Agarwala V., Molnes J., Gupta N., Burtt NP, Florez JC, Meigs JB, Taylor H., Lyssenko V., Irgens H., Fox E., Burslem F., Johansson S., Brosnan MJ, Trimmer JK, Newton-Cheh C., Tuomi T., Molven A., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1380-5, (2013) Read More / View Supplemental Materials
Abstract
2012
The Impact of Ancestry and Common Genetic Variants on QT Interval in African Americans.Smith, JG, Avery CL, Evans DS, Nalls MA, Meng YA, Smith EN, Palmer C., Tanaka T., Mehra R., Butler AM, Young T., Buxbaum SG, Kerr KF, Berenson GS, Schnabel RB, Li G., Ellinor PT, Magnani JW, Chen W., Bis JC, et al. Circulation. Cardiovascular genetics, 2012/11/19, (2012) Read More / View Supplemental Materials
Abstract
QT Interval and Long-Term Mortality Risk in the Framingham Heart Study.Noseworthy, PA, Peloso GM, Hwang SJ, Larson MG, Levy D., O'Donnell CJ, and Newton-Cheh C. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2012/10/01, Volume 17, Issue 4, p.340-348, (2012) Read More / View Supplemental Materials
Abstract
Burden of rare sarcomere gene variants in the framingham and jackson heart study cohorts.Bick, AG, Flannick J., Ito K., Cheng S., Vasan RS, Parfenov MG, Herman DS, Depalma SR, Gupta N., Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J., Taylor HA Jr, Fox ER, Newton-Cheh C., Kathiresan S., O'Donnell CJ, Wilson JG, et al. American journal of human genetics, 2012/09/07, Volume 91, Issue 3, p.513-9, (2012) Read More / View Supplemental Materials
Abstract
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits.Voight, BF, Kang HM, Ding J., Palmer CD, Sidore C., Chines PS, Burtt NP, Fuchsberger C., Li Y., Erdmann J., Frayling TM, Heid IM, Jackson AU, Johnson T., Kilpeläinen TO, Lindgren CM, Morris AP, Prokopenko I., Randall JC, Saxena R., et al. PLoS genetics, 2012/08/01, Volume 8, Issue 8, p.e1002793, (2012) Read More / View Supplemental Materials
Abstract
Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysis.Gustav Smith, J., Almgren P., Engström G., Hedblad B., Platonov PG, Newton-Cheh C., and Melander O. Journal of internal medicine, 2012/06/12, (2012) Read More / View Supplemental Materials
Abstract
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.Voight, BF, Peloso GM, Orho-Melander M., Frikke-Schmidt R., Barbalic M., Jensen MK, Hindy G., Hólm H., Ding EL, Johnson T., Schunkert H., Samani NJ, Clarke R., Hopewell JC, Thompson JF, Li M., Thorleifsson G., Newton-Cheh C., Musunuru K., Pirruccello JP, et al. Lancet, 2012/05/17, (2012) Read More / View Supplemental Materials
Abstract
2011
What can genetic studies of left ventricular mass tell us?Newton-Cheh, C. Circulation. Cardiovascular genetics, 2011/12/01, Volume 4, Issue 6, p.581-4, (2011) Read More / View Supplemental Materials
Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmo Diet and Cancer Study.Magnusson, M., Jujic A., Hedblad B., Engström G., Persson M., Struck J., Morgenthaler NG, Nilsson P., Newton-Cheh C., Wang TJ, and Melander O. The Journal of clinical endocrinology and metabolism, 2011/11/23, (2011) Read More / View Supplemental Materials
Abstract
2010
Candidate gene association resource (CARe): design, methods, and proof of concept.Musunuru, K., Lettre G., Young T., Farlow DN, Pirruccello JP, Ejebe KG, Keating BJ, Yang Q., Chen MH, Lapchyk N., Crenshaw A., Ziaugra L., Rachupka A., Benjamin EJ, Cupples LA, Fornage M., Fox ER, Heckbert SR, Hirschhorn JN, Newton-Cheh C., et al. Circulation. Cardiovascular genetics, 2010/06/01, Volume 3, Issue 3, p.267-75, (2010) Read More / View Supplemental Materials
Abstract
Blood pressure and human genetic variation in the general population.Arora, P., and Newton-Cheh C. Current opinion in cardiology, 2010/03/10, (2010) Read More / View Supplemental Materials
Abstract
2009
Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae.Smith, JG, Lowe JK, Kovvali S., Maller JB, Salit J., Daly M. J., Stoffel M., Altshuler DM, Friedman JM, Breslow JL, and Newton-Cheh C. Heart rhythm : the official journal of the Heart Rhythm Society, 2009/05/01, Volume 6, Issue 5, p.634-41, (2009) Read More / View Supplemental Materials
Abstract
2007
Genetic determinants of QT interval variation and sudden cardiac death.Newton-Cheh, C., and Shah R. Current opinion in genetics & development, 2007/06/01, Volume 17, Issue 3, p.213-21, (2007) Read More / View Supplemental Materials
Abstract
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.and of Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, Novartis Institutes BioMedical Rese, Saxena R., Voight BF, Lyssenko V., Burtt NP, de Bakker PI, Chen H., Roix JJ, Kathiresan S., Hirschhorn JN, Daly M. J., Hughes TE, Groop L., Altshuler D., Almgren P., Florez JC, Meyer J., Ardlie K., Bengtsson Boström K., Isomaa B., et al. Science (New York, N.Y.), 2007/06/01, Volume 316, Issue 5829, p.1331-6, (2007) Read More / View Supplemental Materials
Abstract
2005
Genetic association studies of complex traits: design and analysis issues.Newton-Cheh, C., and Hirschhorn JN Mutation research, 2005/06/03, Volume 573, Issue 1-2, p.54-69, (2005) Read More / View Supplemental Materials
Abstract
  • Showing 1-18 of 18 Results