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  • Showing 1-18 of 18 Results
2014
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.Jaiswal, S., Fontanillas P., Flannick J., Manning A., Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N., Chavez A., Higgins JM, Moltchanov V., Kuo FC, Kluk MJ, Henderson B., Kinnunen L., Koistinen HA, Ladenvall C., Getz G., Correa A., et al. The New England journal of medicine, 2014/11/26, (2014) Read More / View Supplemental Materials
Abstract
Association of Sickle Cell Trait With Chronic Kidney Disease and Albuminuria in African Americans.Naik, RP, Derebail VK, Grams ME, Franceschini N., Auer PL, Peloso GM, Young BA, Lettre G., Peralta CA, Katz R., Hyacinth HI, Quarells RC, Grove ML, Bick AG, Fontanillas P., Rich SS, Smith JD, Boerwinkle E., Rosamond WD, Ito K., et al. JAMA, 2014/11/26, Volume 312, Issue 20, p.2115-2125, (2014) Read More / View Supplemental Materials
Abstract
Leveraging population admixture to characterize the heritability of complex traits.Zaitlen, N., Pasaniuc B., Sankararaman S., Bhatia G., Zhang J., Gusev A., Young T., Tandon A., Pollack S., Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S., Franceschini N., Goodman PG, He J., Hennis AJ, Hsing A., Ingles SA, et al. Nature genetics, 2014/11/10, (2014) Read More / View Supplemental Materials
Abstract
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.Swerdlow, DI, Preiss D., Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T., Sofat R., Stender S., Johnson PC, Scott RA, Leusink M., Verweij N., Sharp SJ, Guo Y., Giambartolomei C., Chung C., Peasey A., Amuzu A., Li K., Palmen J., et al. Lancet, 2014/09/24, (2014) Read More / View Supplemental Materials
Abstract
Association of exome sequences with plasma C-reactive protein levels in >9000 participants.Schick, UM, Auer PL, Bis JC, Lin H., Wei P., Pankratz N., Lange LA, Brody J., Stitziel NO, Kim DS, Carlson CS, Fornage M., Haessler J., Hsu L., Jackson RD, Kooperberg C., Leal SM, Psaty BM, Boerwinkle E., Tracy R., et al. Human molecular genetics, 2014/09/03, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.Du, M., Auer PL, Jiao S., Haessler J., Altshuler D., Boerwinkle E., Carlson CS, Carty CL, Chen YD, Curtis K., Franceschini N., Hsu L., Jackson R., Lange LA, Lettre G., Monda KL, and National Heart, Lung Blood Institute(NHLBI) GO Exome Sequencing Project, Nickerson DA, Reiner AP, Rich SS, et al. Human molecular genetics, 2014/07/15, (2014) Read More / View Supplemental Materials
Abstract
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.and TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung Blood Institute, Crosby J., Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y., Tang ZZ, Zhang H., Hindy G., Masca N., Stirrups K., Kanoni S., Do R., Jun G., Hu Y., Kang HM, Xue C., Goel A., et al. The New England journal of medicine, 2014/07/03, Volume 371, Issue 1, p.22-31, (2014) Read More / View Supplemental Materials
Abstract
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.Flannick, J., Thorleifsson G., Beer NL, Jacobs SB, Grarup N., Burtt NP, Mahajan A., Fuchsberger C., Atzmon G., Benediktsson R., Blangero J., Bowden DW, Brandslund I., Brosnan J., Burslem F., Chambers J., Cho YS, Christensen C., Douglas DA, Duggirala R., et al. Nature genetics, 2014/04/01, Volume 46, Issue 4, p.357-63, (2014) Read More / View Supplemental Materials
Abstract
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.Peloso, GM, Auer PL, Bis JC, Voorman A., Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M., Isaacs A., Jakobsdottir J., Feitosa MF, Davies G., Huffman JE, Manichaikul A., Davis B., Lohman K., Joon AY, Smith AV, et al. American journal of human genetics, 2014/02/06, Volume 94, Issue 2, p.223-32, (2014) Read More / View Supplemental Materials
Abstract
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol.Lange, LA, Hu Y., Zhang H., Xue C., Schmidt EM, Tang ZZ, Bizon C., Lange EM, Smith JD, Turner EH, Jun G., Kang HM, Peloso G., Auer P., Li KP, Flannick J., Zhang J., Fuchsberger C., Gaulton K., Lindgren C., et al. American journal of human genetics, 2014/02/06, Volume 94, Issue 2, p.233-45, (2014) Read More / View Supplemental Materials
Abstract
2013
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.The SIGMA Type 2 Diabetes, Consortium, team Writing, Williams AL, Jacobs SB, Moreno-Macías H., Huerta-Chagoya A., Churchhouse C., Márquez-Luna C., García-Ortíz H., José Gómez-Vázquez M., Burtt NP, Aguilar-Salinas CA, González-Villalpando C., Florez JC, Orozco L., Haiman CA, Tusié-Luna T., Altshuler D., team Analysis, Williams AL, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.Flannick, J., Beer NL, Bick AG, Agarwala V., Molnes J., Gupta N., Burtt NP, Florez JC, Meigs JB, Taylor H., Lyssenko V., Irgens H., Fox E., Burslem F., Johansson S., Brosnan MJ, Trimmer JK, Newton-Cheh C., Tuomi T., Molven A., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1380-5, (2013) Read More / View Supplemental Materials
Abstract
Using population admixture to help complete maps of the human genome.Genovese, G., Handsaker RE, Li H., Altemose N., Lindgren AM, Chambert K., Pasaniuc B., Price AL, Reich D., Morton CC, Pollak MR, Wilson JG, and McCarroll SA Nature genetics, 2013/02/24, (2013) Read More / View Supplemental Materials
Abstract
2012
Burden of rare sarcomere gene variants in the framingham and jackson heart study cohorts.Bick, AG, Flannick J., Ito K., Cheng S., Vasan RS, Parfenov MG, Herman DS, Depalma SR, Gupta N., Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J., Taylor HA Jr, Fox ER, Newton-Cheh C., Kathiresan S., O'Donnell CJ, Wilson JG, et al. American journal of human genetics, 2012/09/07, Volume 91, Issue 3, p.513-9, (2012) Read More / View Supplemental Materials
Abstract
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.Saxena, R., Elbers CC, Guo Y., Peter I., Gaunt TR, Mega JL, Lanktree MB, Tare A., Castillo BA, Li YR, Johnson T., Bruinenberg M., Gilbert-Diamond D., Rajagopalan R., Voight BF, Balasubramanyam A., Barnard J., Bauer F., Baumert J., Bhangale T., et al. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.410-425, (2012) Read More / View Supplemental Materials
Abstract
Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project.Musunuru, K., Romaine SP, Lettre G., Wilson JG, Volcik KA, Tsai MY, Taylor HA Jr, Schreiner PJ, Rotter JI, Rich SS, Redline S., Psaty BM, Papanicolaou GJ, Ordovas JM, Liu K., Krauss RM, Glazer NL, Gabriel SB, Fornage M., Cupples LA, et al. PloS one, 2012/01/01, Volume 7, Issue 5, p.e36473, (2012) Read More / View Supplemental Materials
Abstract
2011
Genome-wide Association of Copy-Number Variation Reveals an Association between Short Stature and the Presence of Low-Frequency Genomic Deletions.Dauber, A., Yu Y., Turchin MC, Chiang CW, Meng YA, Demerath EW, Patel SR, Rich SS, Rotter JI, Schreiner PJ, Wilson JG, Shen Y., Wu BL, and Hirschhorn JN American journal of human genetics, 2011/12/09, Volume 89, Issue 6, p.751-9, (2011) Read More / View Supplemental Materials
Abstract
2010
Candidate gene association resource (CARe): design, methods, and proof of concept.Musunuru, K., Lettre G., Young T., Farlow DN, Pirruccello JP, Ejebe KG, Keating BJ, Yang Q., Chen MH, Lapchyk N., Crenshaw A., Ziaugra L., Rachupka A., Benjamin EJ, Cupples LA, Fornage M., Fox ER, Heckbert SR, Hirschhorn JN, Newton-Cheh C., et al. Circulation. Cardiovascular genetics, 2010/06/01, Volume 3, Issue 3, p.267-75, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-18 of 18 Results