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2016
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.Kar, SP, Beesley J., Amin Al Olama A., Michailidou K., Tyrer J., Kote-Jarai Z., Lawrenson K., Lindstrom S., Ramus SJ, Thompson DJ, ABCTB Investigators, Kibel AS, Dansonka-Mieszkowska A., Michael A., Dieffenbach AK, Gentry-Maharaj A., Whittemore AS, Wolk A., Monteiro A., Peixoto A., et al. Cancer discovery, 2016/07/17, (2016) Read More / View Supplemental Materials
Abstract
Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.Han, Y., Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B., Isaacs WB, Stanford JL, Zheng W., Schumacher FR, Berndt SI, Wang Z., Xu J., Rohland N., Reich D., Tandon A., Pasaniuc B., Allen A., et al. Journal of the National Cancer Institute, 2016/07/01, Volume 108, Issue 7, (2016) Read More / View Supplemental Materials
Abstract
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.Machiela, MJ, Zhou W., Karlins E., Sampson JN, Freedman ND, Yang Q., Hicks B., Dagnall C., Hautman C., Jacobs KB, Abnet CC, Aldrich MC, Amos C., Amundadottir LT, Arslan AA, Beane-Freeman LE, Berndt SI, Black A., Blot WJ, Bock CH, et al. Nature communications, 2016/06/13, Volume 7, p.11843, (2016) Read More / View Supplemental Materials
Abstract
Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.Sajuthi, SP, Sharma NK, Chou JW, Palmer ND, McWilliams DR, Beal J., Comeau ME, Ma L., Calles-Escandon J., Demons J., Rogers S., Cherry K., Menon L., Kouba E., Davis D., Burris M., Byerly SJ, Ng MC, Maruthur NM, Patel SR, et al. Human genetics, 2016/05/19, (2016) Read More / View Supplemental Materials
Abstract
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.Gusev, A., Shi H., Kichaev G., Pomerantz M., Li F., Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B., Isaacs WB, Zheng W., Pettaway CA, Yeboah ED, Tettey Y., Biritwum RB, Adjei AA, Tay E., Truelove A., et al. Nature communications, 2016/04/07, Volume 7, p.10979, (2016) Read More / View Supplemental Materials
Abstract
Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.Figueroa, JD, Middlebrooks CD, Banday AR, Ye Y., Garcia-Closas M., Chatterjee N., Koutros S., Kiemeney LA, Rafnar T., Bishop T., Barnes HF, Matullo G., Golka K., Gago-Dominguez M., Taylor J., Fletcher T., Siddiq A., Cortessis VK, Kooperberg C., Cussenot O., et al. Human molecular genetics, 2016/01/04, (2016) Read More / View Supplemental Materials
Abstract
2015
Whole-exome sequencing of over 4,100 men of African ancestry and prostate cancer risk.Rand, KA, Rohland N., Tandon A., Stram A., Sheng X., Do R., Pasaniuc B., Allen A., Quinque D., Mallick S., Le Marchand L., Kaggwa S., Lubwama A., African Ancestry Prostate Cancer GWAS Consortium, consortium Ellipse/GAME-ON, Stram DO, Watya S., Henderson BE, Conti DV, Reich D., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
Abstract
The contribution of rare variation to prostate cancer heritability.Mancuso, N., Rohland N., Rand KA, Tandon A., Allen A., Quinque D., Mallick S., Li H., Stram A., Sheng X., Kote-Jarai Z., Easton DF, Eeles RA, consortium Practical, Le Marchand L., Lubwama A., Stram D., Watya S., Conti DV, Henderson B., et al. Nature genetics, 2015/11/16, (2015) Read More / View Supplemental Materials
Abstract
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
Abstract
Characterization of large structural genetic mosaicism in human autosomes.Machiela, MJ, Zhou W., Sampson JN, Dean MC, Jacobs KB, Black A., Brinton LA, Chang IS, Chen C., Chen C., Chen K., Cook LS, Crous Bou M., De Vivo I., Doherty J., Friedenreich CM, Gaudet MM, Haiman CA, Hankinson SE, Hartge P., et al. American journal of human genetics, 2015/03/05, Volume 96, Issue 3, p.487-97, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort.Li, Y., Beckman KB, Caberto C., Kazma R., Lum-Jones A., Haiman CA, Marchand LL, Stram DO, Saxena R., and Cheng I. PloS one, 2015/01/01, Volume 10, Issue 9, p.e0136796, (2015) Read More / View Supplemental Materials
Abstract
2014
Genetic Variants Associated with Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.Palmer, ND, Goodarzi MO, Langefeld CD, Wang N., Guo X., Taylor KD, Fingerlin TE, Norris JM, Buchanan TA, Xiang AH, Haritunians T., Ziegler JT, Williams AH, Stefansovski D., Cui J., Mackay AW, Henkin LF, Bergman RN, Gao X., Gauderman J., et al. Diabetes, 2014/12/18, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide Scan of 29,141 African Americans Finds No Evidence of Directional Selection since Admixture.Bhatia, G., Tandon A., Patterson N., Aldrich MC, Ambrosone CB, Amos C., Bandera EV, Berndt SI, Bernstein L., Blot WJ, Bock CH, Caporaso N., Casey G., Deming SL, Diver WR, Gapstur SM, Gillanders EM, Harris CC, Henderson BE, Ingles SA, et al. American journal of human genetics, 2014/09/17, (2014) Read More / View Supplemental Materials
Abstract
Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.Wang, Z., Zhu B., Zhang M., Parikh H., Jia J., Chung CC, Sampson JN, Hoskins JW, Hutchinson A., Burdette L., Ibrahim A., Hautman C., Raj PS, Abnet CC, Adjei AA, Ahlbom A., Albanes D., Allen NE, Ambrosone CB, Aldrich M., et al. Human molecular genetics, 2014/07/15, (2014) Read More / View Supplemental Materials
Abstract
Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.Consortium, SIGMA Type Diabetes 2, Estrada K., Aukrust I., Bjørkhaug L., Burtt NP, Mercader JM, García-Ortiz H., Huerta-Chagoya A., Moreno-Macías H., Walford G., Flannick J., Williams AL, Gómez-Vázquez MJ, Fernandez-Lopez JC, Martínez-Hernández A., Centeno-Cruz F., Mendoza-Caamal E., Revilla-Monsalve C., Islas-Andrade S., Córdova EJ, et al. JAMA : the journal of the American Medical Association, 2014/06/11, Volume 311, Issue 22, p.2305-14, (2014) Read More / View Supplemental Materials
Abstract
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.SIGMA Type 2 Diabetes, Consortium, Williams AL, Jacobs SB, Moreno-Macías H., Huerta-Chagoya A., Churchhouse C., Márquez-Luna C., García-Ortíz H., Gómez-Vázquez MJ, Burtt NP, Aguilar-Salinas CA, González-Villalpando C., Florez JC, Orozco L., Haiman CA, Tusié-Luna T., and Altshuler D. Nature, 2014/02/06, Volume 506, Issue 7486, p.97-101, (2014) Read More / View Supplemental Materials
Abstract
Comprehensive functional annotation of 77 prostate cancer risk Loci.Hazelett, DJ, Rhie SK, Gaddis M., Yan C., Lakeland DL, Coetzee SG, consortium Ellipse/GAME-ON, consortium Practical, Henderson BE, Noushmehr H., Cozen W., Kote-Jarai Z., Eeles RA, Easton DF, Haiman CA, Lu W., Farnham PJ, and Coetzee GA PLoS genetics, 2014/01/01, Volume 10, Issue 1, p.e1004102, (2014) Read More / View Supplemental Materials
Abstract
2011
Transferability of tag SNPs to capture common genetic variation in DNA repair genes across multiple populations.de Bakker, PI, Graham RR, Altshuler D., Henderson BE, and Haiman CA Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2011/12/08, p.478-86, (2011) Read More / View Supplemental Materials
Abstract
2006
Transferability of tag SNPs in genetic association studies in multiple populations.de Bakker, PI, Burtt NP, Graham RR, Guiducci C., Yelensky R., Drake JA, Bersaglieri T., Penney KL, Butler J., Young S., Onofrio RC, Lyon HN, Stram DO, Haiman CA, Freedman ML, Zhu X., Cooper R., Groop L., Kolonel LN, Henderson BE, et al. Nature genetics, 2006/11/01, Volume 38, Issue 11, p.1298-303, (2006) Read More / View Supplemental Materials
Abstract
2005
A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk.Freedman, ML, Penney KL, Stram DO, Riley S., McKean-Cowdin R., Le Marchand L., Altshuler D., and Haiman CA Cancer research, 2005/08/15, Volume 65, Issue 16, p.7516-22, (2005) Read More / View Supplemental Materials
Abstract
2004
Common variation in BRCA2 and breast cancer risk: a haplotype-based analysis in the Multiethnic Cohort.Freedman, ML, Penney KL, Stram DO, Le Marchand L., Hirschhorn JN, Kolonel LN, Altshuler D., Henderson BE, and Haiman CA Human molecular genetics, 2004/10/15, Volume 13, Issue 20, p.2431-41, (2004) Read More / View Supplemental Materials
Abstract
  • Showing 1-24 of 24 Results