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  • Showing 1-9 of 9 Results
2014
Association of Low-Density Lipoprotein Cholesterol-Related Genetic Variants With Aortic Valve Calcium and Incident Aortic Stenosis.Smith, JG, Luk K., Schulz CA, Engert JC, Do R., Hindy G., Rukh G., Dufresne L., Almgren P., Owens DS, Harris TB, Peloso GM, Kerr KF, Wong Q., Smith AV, Budoff MJ, Rotter JI, Cupples LA, Rich S., Kathiresan S., et al. JAMA, 2014/10/26, (2014) Read More / View Supplemental Materials
Abstract
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.and TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung Blood Institute, Crosby J., Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y., Tang ZZ, Zhang H., Hindy G., Masca N., Stirrups K., Kanoni S., Do R., Jun G., Hu Y., Kang HM, Xue C., Goel A., et al. The New England journal of medicine, 2014/07/03, Volume 371, Issue 1, p.22-31, (2014) Read More / View Supplemental Materials
Abstract
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.Peloso, GM, Auer PL, Bis JC, Voorman A., Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M., Isaacs A., Jakobsdottir J., Feitosa MF, Davies G., Huffman JE, Manichaikul A., Davis B., Lohman K., Joon AY, Smith AV, et al. American journal of human genetics, 2014/02/06, Volume 94, Issue 2, p.223-32, (2014) Read More / View Supplemental Materials
Abstract
Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.Hamrefors, V., Hedblad B., Hindy G., Smith JG, Almgren P., Engström G., Sjögren M., Gränsbo K., Orho-Melander M., and Melander O. PloS one, 2014/01/22, Volume 9, Issue 1, p.e85893, (2014) Read More / View Supplemental Materials
Abstract
2013
Meta-analysis of gene-level tests for rare variant association.Liu, DJ, Peloso GM, Zhan X., Holmen OL, Zawistowski M., Feng S., Nikpay M., Auer PL, Goel A., Zhang H., Peters U., Farrall M., Orho-Melander M., Kooperberg C., McPherson R., Watkins H., Willer CJ, Hveem K., Melander O., Kathiresan S., et al. Nature genetics, 2013/12/15, (2013) Read More / View Supplemental Materials
Abstract
Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia.Stitziel, NO, Fouchier SW, Sjouke B., Peloso GM, Moscoso AM, Auer PL, Goel A., Gigante B., Barnes TA, Melander O., Orho-Melander M., Duga S., Sivapalaratnam S., Nikpay M., Martinelli N., Girelli D., Jackson RD, Kooperberg C., Lange LA, Ardissino D., et al. Arteriosclerosis, thrombosis, and vascular biology, 2013/09/26, (2013) Read More / View Supplemental Materials
Abstract
2012
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.Voight, BF, Peloso GM, Orho-Melander M., Frikke-Schmidt R., Barbalic M., Jensen MK, Hindy G., Hólm H., Ding EL, Johnson T., Schunkert H., Samani NJ, Clarke R., Hopewell JC, Thompson JF, Li M., Thorleifsson G., Newton-Cheh C., Musunuru K., Pirruccello JP, et al. Lancet, 2012/05/17, (2012) Read More / View Supplemental Materials
Abstract
2007
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.and of Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, Novartis Institutes BioMedical Rese, Saxena R., Voight BF, Lyssenko V., Burtt NP, de Bakker PI, Chen H., Roix JJ, Kathiresan S., Hirschhorn JN, Daly M. J., Hughes TE, Groop L., Altshuler D., Almgren P., Florez JC, Meyer J., Ardlie K., Bengtsson Boström K., Isomaa B., et al. Science (New York, N.Y.), 2007/06/01, Volume 316, Issue 5829, p.1331-6, (2007) Read More / View Supplemental Materials
Abstract
2006
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.Saxena, R., Gianniny L., Burtt NP, Lyssenko V., Giuducci C., Sjögren M., Florez JC, Almgren P., Isomaa B., Orho-Melander M., Lindblad U., Daly M. J., Tuomi T., Hirschhorn JN, Ardlie KG, Groop LC, and Altshuler D. Diabetes, 2006/10/01, Volume 55, Issue 10, p.2890-5, (2006) Read More / View Supplemental Materials
Abstract
  • Showing 1-9 of 9 Results