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2015
Integrative Clinical Genomics of Advanced Prostate Cancer.Robinson, D., Van Allen EM, Wu YM, Schultz N., Lonigro RJ, Mosquera JM, Montgomery B., Taplin ME, Pritchard CC, Attard G., Beltran H., Abida W., Bradley RK, Vinson J., Cao X., Vats P., Kunju LP, Hussain M., Feng FY, Tomlins SA, et al. Cell, 2015/05/21, Volume 161, Issue 5, p.1215-1228, (2015) Read More / View Supplemental Materials
Abstract
Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues.Tyekucheva, S., Martin NE, Stack EC, Wei W., Vathipadiekal V., Waldron L., Fiorentino M., Lis RT, Stampfer MJ, Loda M., Parmigiani G., Mucci LA, and Birrer M. The Journal of molecular diagnostics : JMD, 2015/04/29, (2015) Read More / View Supplemental Materials
Abstract
DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors.Bambury, RM, Bhatt AS, Riester M., Pedamallu CS, Duke F., Bellmunt J., Stack EC, Werner L., Park R., Iyer G., Loda M., Kantoff PW, Michor F., Meyerson M., and Rosenberg JE BMC cancer, 2015/04/09, Volume 15, p.242, (2015) Read More / View Supplemental Materials
Abstract
Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity.Majumder, B., Baraneedharan U., Thiyagarajan S., Radhakrishnan P., Narasimhan H., Dhandapani M., Brijwani N., Pinto DD, Prasath A., Shanthappa BU, Thayakumar A., Surendran R., Babu GK, Shenoy AM, Kuriakose MA, Bergthold G., Horowitz P., Loda M., Beroukhim R., Agarwal S., et al. Nature communications, 2015/02/27, Volume 6, p.6169, (2015) Read More / View Supplemental Materials
Abstract
2014
FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder.Guancial, EA, Werner L., Bellmunt J., Bamias A., Choueiri TK, Ross R., Schutz FA, Park RS, O'Brien RJ, Hirsch MS, Barletta JA, Berman DM, Lis R., Loda M., Stack EC, Garraway LA, Riester M., Michor F., Kantoff PW, and Rosenberg JE Cancer medicine, 2014/05/21, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.Lohr, JG, Adalsteinsson VA, Cibulskis K., Choudhury AD, Rosenberg M., Cruz-Gordillo P., Francis JM, Zhang CZ, Shalek AK, Satija R., Trombetta JJ, Lu D., Tallapragada N., Tahirova N., Kim S., Blumenstiel B., Sougnez C., Lowe A., Wong B., Auclair D., et al. Nature biotechnology, 2014/05/01, Volume 32, Issue 5, p.479-84, (2014) Read More / View Supplemental Materials
Abstract
Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib.Wagle, N., Grabiner BC, Van Allen EM, Hodis E., Jacobus S., Choueiri TK, Gandhi L., Taplin ME, Stack EC, Signoretti S., Loda M., Shapiro GI, Sabatini DM, Lander E. S., Gabriel SB, Kantoff PW, Garraway LA, and Rosenberg JE Cancer discovery, 2014/03/27, (2014) Read More / View Supplemental Materials
Abstract
De novo fatty acid synthesis at the mitotic exit is required to complete cellular division.Scaglia, N., Tyekucheva S., Zadra G., Photopoulos C., and Loda M. Cell cycle (Georgetown, Tex.), 2014/01/13, Volume 13, Issue 5, (2014) Read More / View Supplemental Materials
Abstract
2013
Gleason Grade Progression Is Uncommon.Penney, KL, Stampfer MJ, Jahn JL, Sinnott JA, Flavin R., Rider JR, Finn S., Giovannucci E., Sesso HD, Loda M., Mucci LA, and Fiorentino M. Cancer research, 2013/08/15, Volume 73, Issue 16, p.5163-5168, (2013) Read More / View Supplemental Materials
Abstract
2012
MYC Is Activated by USP2a-Mediated Modulation of MicroRNAs in Prostate Cancer.Benassi, B., Flavin R., Marchionni L., Zanata S., Pan Y., Chowdhury D., Marani M., Strano S., Muti P., Blandino G., and Loda M. Cancer discovery, 2012/03/01, Volume 2, Issue 3, p.236-247, (2012) Read More / View Supplemental Materials
Abstract
2011
mRNA expression signature of Gleason grade predicts lethal prostate cancer.Penney, KL, Sinnott JA, Fall K., Pawitan Y., Hoshida Y., Kraft P., Stark JR, Fiorentino M., Perner S., Finn S., Calza S., Flavin R., Freedman ML, Setlur S., Sesso HD, Andersson SO, Martin N., Kantoff PW, Johansson JE, Adami HO, et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/06/10, Volume 29, Issue 17, p.2391-6, (2011) Read More / View Supplemental Materials
Abstract
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.Ding, Z., Wu CJ, Chu GC, Xiao Y., Ho D., Zhang J., Perry SR, Labrot ES, Wu X., Lis R., Hoshida Y., Hiller D., Hu B., Jiang S., Zheng H., Stegh AH, Scott KL, Signoretti S., Bardeesy N., Wang YA, et al. Nature, 2011/02/10, Volume 470, Issue 7333, p.269-73, (2011) Read More / View Supplemental Materials
Abstract
2010
The landscape of somatic copy-number alteration across human cancers.Beroukhim, R., Mermel CH, Porter D., Wei G., Raychaudhuri S., Donovan J., Barretina J., Boehm JS, Dobson J., Urashima M., Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L., Greulich H., Reich M., Winckler W., Lawrence MS, Weir BA, et al. Nature, 2010/02/18, Volume 463, Issue 7283, p.899-905, (2010) Read More / View Supplemental Materials
Abstract
2009
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.Du, J., Bernasconi P., Clauser KR, Mani D. R., Finn SP, Beroukhim R., Burns M., Julian B., Peng XP, Hieronymus H., Maglathlin RL, Lewis TA, Liau LM, Nghiemphu P., Mellinghoff IK, Louis DN, Loda M., Carr SA, Kung AL, and Golub T. R. Nature biotechnology, 2009/01/01, Volume 27, Issue 1, p.77-83, (2009) Read More / View Supplemental Materials
Abstract
2007
Identification of prostate cancer modifier pathways using parental strain expression mapping.Xu, Q., Majumder PK, Ross K., Shim Y., Golub T. R., Loda M., and Sellers WR Proceedings of the National Academy of Sciences of the United States of America, 2007/11/06, Volume 104, Issue 45, p.17771-6, (2007) Read More / View Supplemental Materials
Abstract
High-throughput oncogene mutation profiling in human cancer.Thomas, RK, Baker AC, Debiasi RM, Winckler W., LaFramboise T., Lin WM, Wang M., Feng W., Zander T., MacConaill L., Lee JC, Nicoletti R., Hatton C., Goyette M., Girard L., Majmudar K., Ziaugra L., Wong KK, Gabriel S., Beroukhim R., et al. Nature genetics, 2007/03/01, Volume 39, Issue 3, p.347-51, (2007) Read More / View Supplemental Materials
Abstract
Semiautomated multiplexed quantum dot-based in situ hybridization and spectral deconvolution.Byers, RJ, Di Vizio D., O'connell F., Tholouli E., Levenson RM, Gossage K., Twomey D., Yang Y., Benedettini E., Rose J., Ligon KL, Finn SP, Golub T. R., and Loda M. The Journal of molecular diagnostics : JMD, 2007/02/01, Volume 9, Issue 1, p.20-9, (2007) Read More / View Supplemental Materials
Abstract
2006
Imaging of multiple mRNA targets using quantum dot based in situ hybridization and spectral deconvolution in clinical biopsies.Tholouli, E., Hoyland JA, Di Vizio D., O'connell F., Macdermott SA, Twomey D., Levenson R., Yin JA, Golub T. R., Loda M., and Byers R. Biochemical and biophysical research communications, 2006/09/22, Volume 348, Issue 2, p.628-36, (2006) Read More / View Supplemental Materials
Abstract
2005
Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer.Febbo, PG, Lowenberg M., Thorner AR, Brown M., Loda M., and Golub T. R. The Journal of urology, 2005/05/01, Volume 173, Issue 5, p.1772-7, (2005) Read More / View Supplemental Materials
Abstract
2004
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells.Berger, R., Febbo PG, Majumder PK, Zhao JJ, Mukherjee S., Signoretti S., Campbell KT, Sellers WR, Roberts TM, Loda M., Golub T. R., and Hahn WC Cancer research, 2004/12/15, Volume 64, Issue 24, p.8867-75, (2004) Read More / View Supplemental Materials
Abstract
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.Majumder, PK, Febbo PG, Bikoff R., Berger R., Xue Q., McMahon LM, Manola J., Brugarolas J., McDonnell TJ, Golub T. R., Loda M., Lane HA, and Sellers WR Nature medicine, 2004/06/01, Volume 10, Issue 6, p.594-601, (2004) Read More / View Supplemental Materials
Abstract
2001
Multiclass cancer diagnosis using tumor gene expression signaturesRamaswamy, S., Tamayo P., Rifkin R., Mukherjee S., Yeang C. H., Angelo M., Ladd C., Reich M., Latulippe E., Mesirov J. P., Poggio T., Gerald W., Loda M., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2001/12/18/, Volume 98, Issue 26, p.15149 - 54, (2001) Read More / View Supplemental Materials
Abstract
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
Abstract
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
Abstract
  • Showing 1-24 of 24 Results