Recent Broad Publications

A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration.
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Synthesis of Stereochemically and Skeletally Diverse Fused Ring Systems from Functionalized C-Glycosides.
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RhoGTPases - NODes for effector-triggered immunity in animals.
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Comparative analysis of RNA sequencing methods for degraded or low-input samples.
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Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.
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Scientific Publications

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Filters: Author is Roy, J [Clear All Filters]

2007

Genome-wide detection and characterization of positive selection in human populations.Sabeti, PC, Varilly P., Fry B., Lohmueller J., Hostetter E., Cotsapas C., Xie X., Byrne EH, McCarroll SA, Gaudet R., Schaffner SF, Lander E. S., International HapMap Consortium, Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, et al. Nature, 2007/10/18, Volume 449, Issue 7164, p.913-8, (2007) Read More / View Supplemental Materials

2006

Searching for signals of evolutionary selection in 168 genes related to immune function.Walsh, EC, Sabeti P., Hutcheson HB, Fry B., Schaffner SF, de Bakker PI, Varilly P., Palma AA, Roy J., Cooper R., Winkler C., Zeng Y., de The G., Lander E. S., O'Brien S., and Altshuler D. Human genetics, 2006/03/01, Volume 119, Issue 1-2, p.92-102, (2006) Read More / View Supplemental Materials

2005

The case for selection at CCR5-Delta32.Sabeti, PC, Walsh E., Schaffner SF, Varilly P., Fry B., Hutcheson HB, Cullen M., Mikkelsen TS, Roy J., Patterson N., Cooper R., Reich D., Altshuler D., O'Brien S., and Lander E. S. PLoS biology, 2005/11/01, Volume 3, Issue 11, p.e378, (2005) Read More / View Supplemental Materials