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  • Showing 1-8 of 8 Results
2016
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.Drier, Y., Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L., Qi J., Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster J. C., Knoechel B., and Bernstein BE Nature genetics, 2016/02/01, (2016) Read More / View Supplemental Materials
Abstract
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.Hu, SS, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M., Jin Huh S., Liang Y., Ryan J., Doherty E., Mohammed H., Guo H., Stover DG, Ekram MB, Peluffo G., Brown J., D'Santos C., Krop IE, Dillon D., et al. Nature, 2016/01/06, (2016) Read More / View Supplemental Materials
Abstract
2015
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.Chen, CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N., Eng R., Doench JG, Xu H., Chu SH, Qi J., Wang X., Delaney C., Bernt KM, Root DE, Hahn WC, Bradner JE, and Armstrong SA Nature medicine, 2015/03/30, (2015) Read More / View Supplemental Materials
Abstract
2014
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.Tang, Y., Gholamin S., Schubert S., Willardson MI, Lee A., Bandopadhayay P., Bergthold G., Masoud S., Nguyen B., Vue N., Balansay B., Yu F., Oh S., Woo P., Chen S., Ponnuswami A., Monje M., Atwood SX, Whitson RJ, Mitra S., et al. Nature medicine, 2014/07/01, Volume 20, Issue 7, p.732-740, (2014) Read More / View Supplemental Materials
Abstract
2013
Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.Chapuy, B., McKeown MR, Lin CY, Monti S., Roemer MG, Qi J., Rahl PB, Sun HH, Yeda KT, Doench JG, Reichert E., Kung AL, Rodig SJ, Young RA, Shipp M. A., and Bradner JE Cancer cell, 2013/12/09, Volume 24, Issue 6, p.777-90, (2013) Read More / View Supplemental Materials
Abstract
Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation.Frumm, SM, Fan ZP, Ross KN, Duvall JR, Gupta S., VerPlank L., Suh BC, Holson E., Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J., Roti G., Kung AL, Bradner JE, Tolliday N., and Stegmaier K. Chemistry & biology, 2013/05/23, Volume 20, Issue 5, p.713-25, (2013) Read More / View Supplemental Materials
Abstract
Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition.Puissant, A., Frumm SM, Alexe G., Bassil CF, Qi J., Chanthery YH, Nekritz EA, Zeid R., Gustafson WC, Greninger P., Garnett MJ, McDermott U., Benes CH, Kung AL, Weiss WA, Bradner JE, and Stegmaier K. Cancer discovery, 2013/03/01, Volume 3, Issue 3, p.308-323, (2013) Read More / View Supplemental Materials
Abstract
2008
Sequencing the nuclear genome of the extinct woolly mammoth.Miller, W., Drautz DI, Ratan A., Pusey B., Qi J., Lesk AM, Tomsho LP, Packard MD, Zhao F., Sher A., Tikhonov A., Raney B., Patterson N., Lindblad-Toh K., Lander E. S., Knight JR, Irzyk GP, Fredrikson KM, Harkins TT, Sheridan S., et al. Nature, 2008/11/20, Volume 456, Issue 7220, p.387-90, (2008) Read More / View Supplemental Materials
Abstract
  • Showing 1-8 of 8 Results