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2009
Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold.Bowers, AA, West N., Newkirk TL, Troutman-Youngman AE, Schreiber SL, Wiest O., Bradner JE, and Williams RM Organic letters, 2009/03/19, Volume 11, Issue 6, p.1301-4, (2009) Read More / View Supplemental Materials
Abstract
Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole.Bowers, AA, Greshock TJ, West N., Estiu G., Schreiber SL, Wiest O., Williams RM, and Bradner JE Journal of the American Chemical Society, 2009/03/04, Volume 131, Issue 8, p.2900-5, (2009) Read More / View Supplemental Materials
Abstract
2008
Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.Bowers, A., West N., Taunton J., Schreiber SL, Bradner JE, and Williams RM Journal of the American Chemical Society, 2008/08/20, Volume 130, Issue 33, p.11219-22, (2008) Read More / View Supplemental Materials
Abstract
  • Showing 1-3 of 3 Results