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2015
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.Herman, JD, Pepper LR, Cortese JF, Estiu G., Galinsky K., Zuzarte-Luis V., Derbyshire ER, Ribacke U., Lukens AK, Santos SA, Patel V., Clish CB, Sullivan WJ Jr, Zhou H., Bopp SE, Schimmel P., Lindquist S., Clardy J., Mota MM, Keller TL, et al. Science translational medicine, 2015/05/20, Volume 7, Issue 288, p.288ra77, (2015) Read More / View Supplemental Materials
Abstract
2011
Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors.Dong, CK, Urgaonkar S., Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V., Ross L., Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M., Barker RH Jr, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J., and Mazitschek R. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011) Read More / View Supplemental Materials
Abstract
2009
Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.Patel, V., Mazitschek R., Coleman B., Nguyen C., Urgaonkar S., Cortese J., Barker RH, Greenberg E., Tang W., Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, and Clardy J. Journal of medicinal chemistry, 2009/04/23, Volume 52, Issue 8, p.2185-7, (2009) Read More / View Supplemental Materials
Abstract
2008
Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum.Martyn, DC, Ramirez AP, Beattie MJ, Cortese JF, Patel V., Rush MA, Woerpel KA, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/12/15, Volume 18, Issue 24, p.6521-4, (2008) Read More / View Supplemental Materials
Abstract
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.Mazitschek, R., Patel V., Wirth DF, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/05/01, Volume 18, Issue 9, p.2809-12, (2008) Read More / View Supplemental Materials
Abstract
  • Showing 1-5 of 5 Results