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  • Showing 1-12 of 12 Results
2014
Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma.Moore, NF, Azarova AM, Bhatnagar N., Ross KN, Drake LE, Frumm S., Liu QS, Christie AL, Sanda T., Chesler L., Kung AL, Gray NS, Stegmaier K., and George RE Oncotarget, 2014/08/19, (2014) Read More / View Supplemental Materials
Abstract
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.Saha, SK, Parachoniak CA, Ghanta KS, Fitamant J., Ross KN, Najem MS, Gurumurthy S., Akbay EA, Sia D., Cornella H., Miltiadous O., Walesky C., Deshpande V., Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J., Popovici-Muller J., Gliser C., et al. Nature, 2014/07/02, (2014) Read More / View Supplemental Materials
Abstract
2013
Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation.Frumm, SM, Fan ZP, Ross KN, Duvall JR, Gupta S., VerPlank L., Suh BC, Holson E., Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J., Roti G., Kung AL, Bradner JE, Tolliday N., and Stegmaier K. Chemistry & biology, 2013/05/23, Volume 20, Issue 5, p.713-25, (2013) Read More / View Supplemental Materials
Abstract
2011
A method for high-throughput gene expression signature analysis.Peck, D., Crawford ED, Ross KN, Stegmaier K., Golub T. R., and Lamb J. Genome biology, 2011/12/08, Volume 7, Issue 7, p.R61, (2011) Read More / View Supplemental Materials
Abstract
2009
Proteomic and genetic approaches identify Syk as an AML target.Hahn, CK, Berchuck JE, Ross KN, Kakoza RM, Clauser K., Schinzel AC, Ross L., Galinsky I., Davis TN, Silver SJ, Root DE, Stone RM, DeAngelo DJ, Carroll M., Hahn WC, Carr SA, Golub T. R., Kung AL, and Stegmaier K. Cancer cell, 2009/10/06, Volume 16, Issue 4, p.281-94, (2009) Read More / View Supplemental Materials
Abstract
Identification of AML1-ETO modulators by chemical genomics.Corsello, SM, Roti G., Ross KN, Chow KT, Galinsky I., DeAngelo DJ, Stone RM, Kung AL, Golub T. R., and Stegmaier K. Blood, 2009/06/11, Volume 113, Issue 24, p.6193-205, (2009) Read More / View Supplemental Materials
Abstract
2008
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.Hahn, CK, Ross KN, Warrington IM, Mazitschek R., Kanegai CM, Wright RD, Kung AL, Golub T. R., and Stegmaier K. Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15, Volume 105, Issue 28, p.9751-6, (2008) Read More / View Supplemental Materials
Abstract
2007
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.Stegmaier, K., Wong JS, Ross KN, Chow KT, Peck D., Wright RD, Lessnick SL, Kung AL, and Golub T. R. PLoS medicine, 2007/04/01, Volume 4, Issue 4, p.e122, (2007) Read More / View Supplemental Materials
Abstract
2006
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.Hieronymus, H., Lamb J., Ross KN, Peng XP, Clement C., Rodina A., Nieto M., Du J., Stegmaier K., Raj SM, Maloney KN, Clardy J., Hahn WC, Chiosis G., and Golub T. R. Cancer cell, 2006/10/01, Volume 10, Issue 4, p.321-30, (2006) Read More / View Supplemental Materials
Abstract
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.Lamb, J., Crawford ED, Peck D., Modell JW, Blat IC, Wrobel MJ, Lerner J., Brunet JP, Subramanian A., Ross KN, Reich M., Hieronymus H., Wei G., Armstrong SA, Haggarty SJ, Clemons PA, Wei R., Carr SA, Lander E. S., and Golub T. R. Science (New York, N.Y.), 2006/09/29, Volume 313, Issue 5795, p.1929-35, (2006) Read More / View Supplemental Materials
Abstract
2005
Gefitinib induces myeloid differentiation of acute myeloid leukemia.Stegmaier, K., Corsello SM, Ross KN, Wong JS, DeAngelo DJ, and Golub T. R. Blood, 2005/10/15, Volume 106, Issue 8, p.2841-8, (2005) Read More / View Supplemental Materials
Abstract
2004
Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.Stegmaier, K., Ross KN, Colavito SA, O'Malley S., Stockwell BR, and Golub T. R. Nature genetics, 2004/03/01, Volume 36, Issue 3, p.257-63, (2004) Read More / View Supplemental Materials
Abstract
  • Showing 1-12 of 12 Results