Recent Broad Publications
- RhoGTPases - NODes for effector-triggered immunity in animals.
Read More / View Supplemental Materials - Comparative analysis of RNA sequencing methods for degraded or low-input samples.
Read More / View Supplemental Materials - Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.
Read More / View Supplemental Materials - Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.
Read More / View Supplemental Materials - Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.
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Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies. ACS medicinal chemistry letters, 2012/10/11, Volume 3, Issue 10, p.808-813, (2012)
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Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog. Bioorganic & medicinal chemistry letters, 2009/11/15, Volume 19, Issue 22, p.6319-25, (2009)
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A small molecule that binds Hedgehog and blocks its signaling in human cells. Nature chemical biology, 2009/03/01, Volume 5, Issue 3, p.154-6, (2009)
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