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  • Showing 1-6 of 6 Results
2012
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability.Luo, T., Masson K., Jaffe JD, Silkworth W., Ross NT, Scherer CA, Scholl C., Fröhling S., Carr SA, Stern AM, Schreiber SL, and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.2860-5, (2012) Read More / View Supplemental Materials
Abstract
2009
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.Barbie, DA, Tamayo P., Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P., Meylan E., Scholl C., Fröhling S., Chan EM, Sos ML, Michel K., Mermel C., Silver SJ, Weir BA, Reiling JH, Sheng Q., Gupta PB, et al. Nature, 2009/11/05, Volume 462, Issue 7269, p.108-12, (2009) Read More / View Supplemental Materials
Abstract
2008
Activating mutations in ALK provide a therapeutic target in neuroblastoma.George, RE, Sanda T., Hanna M., Fröhling S., Luther W 2nd, Zhang J., Ahn Y., Zhou W., London WB, McGrady P., Xue L., Zozulya S., Gregor VE, Webb TR, Gray NS, Gilliland DG, Diller L., Greulich H., Morris SW, Meyerson M., et al. Nature, 2008/10/16, Volume 455, Issue 7215, p.975-8, (2008) Read More / View Supplemental Materials
Abstract
Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.Tam, WF, Gu TL, Chen J., Lee BH, Bullinger L., Fröhling S., Wang A., Monti S., Golub T. R., and Gilliland DG Blood, 2008/09/01, Volume 112, Issue 5, p.1981-92, (2008) Read More / View Supplemental Materials
Abstract
2007
Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles.Fröhling, S., Scholl C., Levine RL, Loriaux M., Boggon TJ, Bernard OA, Berger R., Döhner H., Döhner K., Ebert BL, Teckie S., Golub T. R., Jiang J., Schittenhelm MM, Lee BH, Griffin JD, Stone RM, Heinrich MC, Deininger MW, Druker BJ, et al. Cancer cell, 2007/12/01, Volume 12, Issue 6, p.501-13, (2007) Read More / View Supplemental Materials
Abstract
2005
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.Levine, RL, Wadleigh M., Cools J., Ebert BL, Wernig G., Huntly BJ, Boggon TJ, Wlodarska I., Clark JJ, Moore S., Adelsperger J., Koo S., Lee JC, Gabriel S., Mercher T., D'Andrea A., Fröhling S., Döhner K., Marynen P., Vandenberghe P., et al. Cancer cell, 2005/04/01, Volume 7, Issue 4, p.387-97, (2005) Read More / View Supplemental Materials
Abstract
  • Showing 1-6 of 6 Results