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2010
Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles.Tassa, C., Duffner JL, Lewis TA, Weissleder R., Schreiber SL, Koehler AN, and Shaw SY Bioconjugate chemistry, 2010/01/01, Volume 21, Issue 1, p.14-9, (2010) Read More / View Supplemental Materials
Abstract
2009
A small molecule that binds Hedgehog and blocks its signaling in human cells.Stanton, BZ, Peng LF, Maloof N., Nakai K., Wang X., Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A., and Schreiber SL Nature chemical biology, 2009/03/01, Volume 5, Issue 3, p.154-6, (2009) Read More / View Supplemental Materials
Abstract
2008
Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity.Nieland, TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S., Zannis VI, Kirchhausen T., and Krieger M. Biochemistry, 2008/01/08, Volume 47, Issue 1, p.460-72, (2008) Read More / View Supplemental Materials
Abstract
2007
Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.Nieland, TJ, Shaw JT, Jaipuri FA, Maliga Z., Duffner JL, Koehler AN, and Krieger M. Journal of lipid research, 2007/08/01, Volume 48, Issue 8, p.1832-45, (2007) Read More / View Supplemental Materials
Abstract
A pipeline for ligand discovery using small-molecule microarrays.Duffner, JL, Clemons PA, and Koehler AN Current opinion in chemical biology, 2007/02/01, Volume 11, Issue 1, p.74-82, (2007) Read More / View Supplemental Materials
Abstract
Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules.Miao, H., Tallarico JA, Hayakawa H., Münger K., Duffner JL, Koehler AN, Schreiber SL, and Lewis TA Journal of combinatorial chemistry, 1969/12/31, Volume 9, Issue 2, p.245-53, (2007) Read More / View Supplemental Materials
Abstract
2006
A robust small-molecule microarray platform for screening cell lysates.Bradner, JE, McPherson OM, Mazitschek R., Barnes-Seeman D., Shen JP, Dhaliwal J., Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P., Schreiber SL, and Koehler AN Chemistry & biology, 2006/05/01, Volume 13, Issue 5, p.493-504, (2006) Read More / View Supplemental Materials
Abstract
  • Showing 1-7 of 7 Results