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  • Showing 1-28 of 28 Results
2016
Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease.Ngo, D., Sinha S., Shen D., Kuhn EW, Keyes MJ, Shi X., Benson MD, O'Sullivan JF, Keshishian H., Farrell LA, Fifer MA, Vasan RS, Sabatine MS, Larson MG, Carr SA, Wang TJ, and Gerszten RE Circulation, 2016/07/26, Volume 134, Issue 4, p.270-85, (2016) Read More / View Supplemental Materials
Abstract
An exome array study of the plasma metabolome.Rhee, EP, Yang Q., Yu B., Liu X., Cheng S., Deik A., Pierce KA, Bullock K., Ho JE, Levy D., Florez JC, Kathiresan S., Larson MG, Vasan RS, Clish CB, Wang TJ, Boerwinkle E., O'Donnell CJ, and Gerszten RE Nature communications, 2016/07/25, Volume 7, p.12360, (2016) Read More / View Supplemental Materials
Abstract
Relations of Arterial Stiffness and Brachial Flow-Mediated Dilation With New-Onset Atrial Fibrillation: The Framingham Heart Study.Shaikh, AY, Wang N., Yin X., Larson MG, Vasan RS, Hamburg NM, Magnani JW, Ellinor PT, Lubitz SA, Mitchell GF, Benjamin EJ, and McManus DD Hypertension, 2016/07/25, (2016) Read More / View Supplemental Materials
Abstract
Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study).Kim, EJ, Yin X., Fontes JD, Magnani JW, Lubitz SA, McManus DD, Seshadri S., Vasan RS, Ellinor PT, Larson MG, Benjamin EJ, and Rienstra M. American heart journal, 2016/07/01, Volume 177, p.138-44, (2016) Read More / View Supplemental Materials
Abstract
Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation.Schnabel, RB, Maas R., Wang N., Yin X., Larson MG, Levy D., Ellinor PT, Lubitz SA, McManus DD, Magnani JW, Atzler D., Böger RH, Schwedhelm E., Vasan RS, and Benjamin EJ American heart journal, 2016/06/01, Volume 176, p.100-6, (2016) Read More / View Supplemental Materials
Abstract
Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study.Spartano, NL, Lyass A., Larson MG, Lewis GD, and Vasan RS Journal of the American Heart Association, 2016/05/27, Volume 5, Issue 6, (2016) Read More / View Supplemental Materials
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Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure.Smith, JG, Felix JF, Morrison AC, Kalogeropoulos A., Trompet S., Wilk JB, Gidlöf O., Wang X., Morley M., Mendelson M., Joehanes R., Ligthart S., Shan X., Bis JC, Wang YA, Sjögren M., Ngwa J., Brandimarto J., Stott DJ, Aguilar D., et al. PLoS genetics, 2016/05/01, Volume 12, Issue 5, p.e1006034, (2016) Read More / View Supplemental Materials
Abstract
Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later.Spartano, NL, Himali JJ, Beiser AS, Lewis GD, Decarli C., Vasan RS, and Seshadri S. Neurology, 2016/02/10, (2016) Read More / View Supplemental Materials
Abstract
Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved vs. Reduced Ejection Fraction.Santhanakrishnan, R., Wang N., Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S., Vasan RS, Lee DS, Wang TJ, Levy D., Benjamin EJ, and Ho JE Circulation, 2016/01/08, (2016) Read More / View Supplemental Materials
Abstract
Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes.Ho, JE, Larson MG, Ghorbani A., Cheng S., Chen MH, Keyes M., Rhee EP, Clish CB, Vasan RS, Gerszten RE, and Wang TJ PloS one, 2016/01/01, Volume 11, Issue 2, p.e0148361, (2016) Read More / View Supplemental Materials
Abstract
2015
Genetic association analyses highlight biological pathways underlying mitral valve prolapse.Dina, C., Bouatia-Naji N., Tucker N., Delling FN, Toomer K., Durst R., Perrocheau M., Fernandez-Friera L., Solis J., investigators PROMESA, Le Tourneau T., Chen MH, Probst V., Bosse Y., Pibarot P., Zelenika D., Lathrop M., Hercberg S., Roussel R., Benjamin EJ, et al. Nature genetics, 2015/08/24, (2015) Read More / View Supplemental Materials
Abstract
Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.Jansen, H., Loley C., Lieb W., Pencina MJ, Nelson CP, Kathiresan S., Peloso GM, Voight BF, Reilly MP, Assimes TL, Boerwinkle E., Hengstenberg C., Laaksonen R., McPherson R., Roberts R., Thorsteinsdottir U., Peters A., Gieger C., Rawal R., Thompson JR, et al. Atherosclerosis, 2015/06/03, Volume 241, Issue 2, p.419-426, (2015) Read More / View Supplemental Materials
Abstract
50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study.Schnabel, RB, Yin X., Gona P., Larson MG, Beiser AS, McManus DD, Newton-Cheh C., Lubitz SA, Magnani JW, Ellinor PT, Seshadri S., Wolf PA, Vasan RS, Benjamin EJ, and Levy D. Lancet, 2015/05/07, (2015) Read More / View Supplemental Materials
Abstract
Distinct metabolomic signatures are associated with longevity in humans.Cheng, S., Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A., Magnusson M., Souza AL, Deik AA, Pierce KA, Bullock K., O'Donnell CJ, Melander O., Clish CB, Vasan RS, Gerszten RE, and Wang TJ Nature communications, 2015/04/13, Volume 6, p.6791, (2015) Read More / View Supplemental Materials
Abstract
Metabolite Profiling and Cardiovascular Event Risk: A Prospective Study of Three Population-Based Cohorts.Würtz, P., Havulinna AS, Soininen P., Tynkkynen T., Prieto-Merino D., Tillin T., Ghorbani A., Artati A., Wang Q., Tiainen M., Kangas AJ, Kettunen J., Kaikkonen J., Mikkilä V., Jula A., Kähönen M., Lehtimäki T., Lawlor DA, Gaunt TR, Hughes AD, et al. Circulation, 2015/01/08, (2015) Read More / View Supplemental Materials
Abstract
2014
Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci.Tragante, V., Barnes MR, Ganesh SK, Lanktree MB, Guo W., Franceschini N., Smith EN, Johnson T., Holmes MV, Padmanabhan S., Karczewski KJ, Almoguera B., Barnard J., Baumert J., Chang YP, Elbers CC, Farrall M., Fischer ME, Gaunt TR, Gho JM, et al. American journal of human genetics, 2014/02/19, (2014) Read More / View Supplemental Materials
Abstract
2013
2-Aminoadipic acid is a biomarker for diabetes risk.Wang, TJ, Ngo D., Psychogios N., Dejam A., Larson MG, Vasan RS, Ghorbani A., O'Sullivan J., Cheng S., Rhee EP, Sinha S., McCabe E., Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M., Pierce KA, Souza AL, Yu Y., et al. The Journal of clinical investigation, 2013/10/01, Volume 123, Issue 10, p.4309-17, (2013) Read More / View Supplemental Materials
Abstract
Metabolite profiles during oral glucose challenge.Ho, JE, Larson MG, Vasan RS, Ghorbani A., Cheng S., Rhee EP, Florez JC, Clish CB, Gerszten RE, and Wang TJ Diabetes, 2013/08/01, Volume 62, Issue 8, p.2689-98, (2013) Read More / View Supplemental Materials
Abstract
A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort.Rhee, EP, Ho JE, Chen MH, Shen D., Cheng S., Larson MG, Ghorbani A., Shi X., Helenius IT, O'Donnell CJ, Souza AL, Deik A., Pierce KA, Bullock K., Walford GA, Vasan RS, Florez JC, Clish C., Yeh JR, Wang TJ, et al. Cell metabolism, 2013/07/02, Volume 18, Issue 1, p.130-43, (2013) Read More / View Supplemental Materials
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A combined epidemiologic and metabolomic approach improves CKD prediction.Rhee, EP, Clish CB, Ghorbani A., Larson MG, Elmariah S., McCabe E., Yang Q., Cheng S., Pierce K., Deik A., Souza AL, Farrell L., Domos C., Yeh RW, Palacios I., Rosenfield K., Vasan RS, Florez JC, Wang TJ, Fox CS, et al. Journal of the American Society of Nephrology : JASN, 2013/07/01, Volume 24, Issue 8, p.1330-8, (2013) Read More / View Supplemental Materials
Abstract
Multiple Inflammatory Biomarkers in Relation to Cardiovascular Events and Mortality in the Community.Schnabel, RB, Yin X., Larson MG, Yamamoto JF, Fontes JD, Kathiresan S., Rong J., Levy D., Keaney JF Jr, Wang TJ, Murabito JM, Vasan RS, and Benjamin EJ Arteriosclerosis, thrombosis, and vascular biology, 2013/05/02, (2013) Read More / View Supplemental Materials
Abstract
2012
Burden of rare sarcomere gene variants in the framingham and jackson heart study cohorts.Bick, AG, Flannick J., Ito K., Cheng S., Vasan RS, Parfenov MG, Herman DS, Depalma SR, Gupta N., Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J., Taylor HA Jr, Fox ER, Newton-Cheh C., Kathiresan S., O'Donnell CJ, Wilson JG, et al. American journal of human genetics, 2012/09/07, Volume 91, Issue 3, p.513-9, (2012) Read More / View Supplemental Materials
Abstract
Metabolite profiling identifies pathways associated with metabolic risk in humans.Cheng, S., Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D., Palma MJ, Roberts LD, Dejam A., Souza AL, Deik AA, Magnusson M., Fox CS, O'Donnell CJ, Vasan RS, Melander O., Clish CB, Gerszten RE, and Wang TJ Circulation, 2012/05/08, Volume 125, Issue 18, p.2222-31, (2012) Read More / View Supplemental Materials
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2011
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.Rhee, EP, Cheng S., Larson MG, Walford GA, Lewis GD, McCabe E., Yang E., Farrell L., Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, and Gerszten RE The Journal of clinical investigation, 2011/04/01, Volume 121, Issue 4, p.1402-11, (2011) Read More / View Supplemental Materials
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Metabolite profiles and the risk of developing diabetes.Wang, TJ, Larson MG, Vasan RS, Cheng S., Rhee EP, McCabe E., Lewis GD, Fox CS, Jacques PF, Fernandez C., O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A., Melander O., Clish CB, and Gerszten RE Nature medicine, 2011/04/01, Volume 17, Issue 4, p.448-53, (2011) Read More / View Supplemental Materials
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2010
Candidate gene association resource (CARe): design, methods, and proof of concept.Musunuru, K., Lettre G., Young T., Farlow DN, Pirruccello JP, Ejebe KG, Keating BJ, Yang Q., Chen MH, Lapchyk N., Crenshaw A., Ziaugra L., Rachupka A., Benjamin EJ, Cupples LA, Fornage M., Fox ER, Heckbert SR, Hirschhorn JN, Newton-Cheh C., et al. Circulation. Cardiovascular genetics, 2010/06/01, Volume 3, Issue 3, p.267-75, (2010) Read More / View Supplemental Materials
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Metabolic signatures of exercise in human plasma.Lewis, GD, Farrell L., Wood MJ, Martinovic M., Arany Z., Rowe GC, Souza A., Cheng S., McCabe EL, Yang E., Shi X., Deo R., Roth FP, Asnani A., Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, et al. Science translational medicine, 2010/05/26, Volume 2, Issue 33, p.33ra37, (2010) Read More / View Supplemental Materials
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2008
Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.Shaham, O., Wei R., Wang TJ, Ricciardi C., Lewis GD, Vasan RS, Carr SA, Thadhani R., Gerszten RE, and Mootha VK Molecular systems biology, 2008/01/01, Volume 4, p.214, (2008) Read More / View Supplemental Materials
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  • Showing 1-28 of 28 Results