New Publications

Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers.
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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
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Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells.
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Absolute quantification of somatic DNA alterations in human cancer.
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RNA-SeQC: RNA-seq metrics for quality control and process optimization.
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Scientific Publications

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2012

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.Barretina, J., Caponigro G., Stransky N., Venkatesan K., Margolin AA, Kim S., Wilson CJ, Lehár J., Kryukov GV, Sonkin D., Reddy A., Liu M., Murray L., Berger MF, Monahan JE, Morais P., Meltzer J., Korejwa A., Jané-Valbuena J., Mapa FA, et al. Nature, 2012/03/28, Volume 483, Issue 7391, p.603-7, (2012) Read More / View Supplemental Materials

2010

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.Barretina, J., Taylor BS, Banerji S., Ramos AH, Lagos-Quintana M., Decarolis PL, Shah K., Socci ND, Weir BA, Ho A., Chiang DY, Reva B., Mermel CH, Getz G., Antipin Y., Beroukhim R., Major JE, Hatton C., Nicoletti R., Hanna M., et al. Nature genetics, 2010/08/01, Volume 42, Issue 8, p.715-21, (2010) Read More / View Supplemental Materials

2008

Drug-sensitive FGFR2 mutations in endometrial carcinoma.Dutt, A., Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C., Nicoletti R., Winckler W., Grewal R., Hanna M., Wyhs N., Ziaugra L., Richter DJ, Trovik J., Engelsen IB, Stefansson IM, Fennell T., Cibulskis K., Zody MC, Akslen LA, et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/06/24, Volume 105, Issue 25, p.8713-7, (2008) Read More / View Supplemental Materials

2007

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma.Beroukhim, R., Getz G., Nghiemphu L., Barretina J., Hsueh T., Linhart D., Vivanco I., Lee JC, Huang JH, Alexander S., Du J., Kau T., Thomas RK, Shah K., Soto H., Perner S., Prensner J., Debiasi RM, Demichelis F., Hatton C., et al. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11, Volume 104, Issue 50, p.20007-12, (2007) Read More / View Supplemental Materials

High-throughput oncogene mutation profiling in human cancer.Thomas, RK, Baker AC, Debiasi RM, Winckler W., LaFramboise T., Lin WM, Wang M., Feng W., Zander T., MacConaill L., Lee JC, Nicoletti R., Hatton C., Goyette M., Girard L., Majmudar K., Ziaugra L., Wong KK, Gabriel S., Beroukhim R., et al. Nature genetics, 2007/03/01, Volume 39, Issue 3, p.347-51, (2007) Read More / View Supplemental Materials