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  • Showing 1-7 of 7 Results
2015
Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.Chattopadhyay, S., Stewart AL, Mukherjee S., Huang C., Hartwell KA, Miller PG, Subramanian R., Carmody LC, Yusuf RZ, Sykes DB, Paulk J., Vetere A., Vallet S., Santo L., Cirstea DD, Hideshima T., Dančík V., Majireck MM, Hussain MM, Singh S., et al. Cell reports, 2015/02/04, (2015) Read More / View Supplemental Materials
Abstract
2014
Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis.Wang, YH, Israelsen WJ, Lee D., Yu VW, Jeanson NT, Clish CB, Cantley LC, Vander Heiden MG, and Scadden DT Cell, 2014/09/11, Volume 158, Issue 6, p.1309-23, (2014) Read More / View Supplemental Materials
Abstract
2013
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.Hartwell, KA, Miller PG, Mukherjee S., Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M., Järås M., Puram R., Dancik V., Al-Shahrour F., Kindler T., Tothova Z., Chattopadhyay S., Hasaka T., Narayan R., Dai M., Huang C., Shterental S., et al. Nature chemical biology, 2013/12/01, Volume 9, Issue 12, p.840-8, (2013) Read More / View Supplemental Materials
Abstract
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling.Miller, PG, Al-Shahrour F., Hartwell KA, Chu LP, Järås M., Puissant A., McConkey ME, Cowley GS, Shterental S., Alexe G., Armstrong SA, Root DE, Scadden DT, Hynes R. O., Mukherjee S., Stegmaier K., and Ebert BL Cancer cell, 2013/06/11, (2013) Read More / View Supplemental Materials
Abstract
2012
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.Kalaitzidis, D., Sykes SM, Wang Z., Punt N., Tang Y., Ragu C., Sinha AU, Lane SW, Souza AL, Clish CB, Anastasiou D., Gilliland DG, Scadden DT, Guertin DA, and Armstrong SA Cell stem cell, 2012/09/07, Volume 11, Issue 3, p.429-39, (2012) Read More / View Supplemental Materials
Abstract
2010
MicroRNA miR-125a controls hematopoietic stem cell number.Guo, S., Lu J., Schlanger R., Zhang H., Wang JY, Fox MC, Purton LE, Fleming HH, Cobb B., Merkenschlager M., Golub T. R., and Scadden DT Proceedings of the National Academy of Sciences of the United States of America, 2010/08/10, Volume 107, Issue 32, p.14229-34, (2010) Read More / View Supplemental Materials
Abstract
2008
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.Lu, J., Guo S., Ebert BL, Zhang H., Peng X., Bosco J., Pretz J., Schlanger R., Wang JY, Mak RH, Dombkowski DM, Preffer FI, Scadden DT, and Golub T. R. Developmental cell, 2008/06/01, Volume 14, Issue 6, p.843-53, (2008) Read More / View Supplemental Materials
Abstract
  • Showing 1-7 of 7 Results