Recent Broad Publications

Hopping between Differentiation States in Lung Adenocarcinoma.
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Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
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The Genome of Anopheles darlingi, the main neotropical malaria vector.
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ATHLATES: accurate typing of human leukocyte antigen through exome sequencing.
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Integrated proteomic analysis of post-translational modifications by serial enrichment.
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Scientific Publications

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Filters: Author is Urgaonkar, S [Clear All Filters]

2011

Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.Urgaonkar, S., Cortese JF, Patel V., Ross L., Clish CB, Serrano AE, Cromwell M., Duraisingh MT, Wirth DF, Clardy J., and Mazitschek R. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011) Read More / View Supplemental Materials

2010

A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity.Urgaonkar, S., Cortese JF, Barker RH, Cromwell M., Serrano AE, Wirth DF, Clardy J., and Mazitschek R. Organic letters, 2010/09/17, Volume 12, Issue 18, p.3998-4001, (2010) Read More / View Supplemental Materials

2009

Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.Patel, V., Mazitschek R., Coleman B., Nguyen C., Urgaonkar S., Cortese J., Barker RH, Greenberg E., Tang W., Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, and Clardy J. Journal of medicinal chemistry, 2009/04/23, Volume 52, Issue 8, p.2185-7, (2009) Read More / View Supplemental Materials

2007

N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli.Mukherjee, S., Robinson CA, Howe AG, Mazor T., Wood PA, Urgaonkar S., Hebert AM, Raychaudhuri D., and Shaw JT Bioorganic & medicinal chemistry letters, 2007/12/01, Volume 17, Issue 23, p.6651-5, (2007) Read More / View Supplemental Materials

Synthesis of kaempferitrin.Urgaonkar, S., and Shaw JT The Journal of organic chemistry, 2007/06/08, Volume 72, Issue 12, p.4582-5, (2007) Read More / View Supplemental Materials

2005

Synthesis of antimicrobial natural products targeting FtsZ: (+/-)-dichamanetin and (+/-)-2' ''-hydroxy-5' '-benzylisouvarinol-B.Urgaonkar, S., La Pierre HS, Meir I., Lund H., Raychaudhuri D., and Shaw JT Organic letters, 2005/12/08, Volume 7, Issue 25, p.5609-12, (2005) Read More / View Supplemental Materials