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2016
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.Zheng, J., Erzurumluoglu AM, Elsworth BL, Kemp JP, Howe L., Haycock PC, Hemani G., Tansey K., Laurin C., Early Genetics and Lifecourse Epidemiology(EAGLE) Eczema Consortium, Pourcain BS, Warrington NM, Finucane HK, Price AL, Bulik-Sullivan BK, Anttila V., Paternoster L., Gaunt TR, Evans DM, and Neale BM Bioinformatics (Oxford, England), 2016/09/22, (2016) Read More / View Supplemental Materials
Abstract
Fast and accurate long-range phasing in a UK Biobank cohort.Loh, PR, Palamara PF, and Price AL Nature genetics, 2016/06/06, (2016) Read More / View Supplemental Materials
Abstract
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.Gusev, A., Shi H., Kichaev G., Pomerantz M., Li F., Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B., Isaacs WB, Zheng W., Pettaway CA, Yeboah ED, Tettey Y., Biritwum RB, Adjei AA, Tay E., Truelove A., et al. Nature communications, 2016/04/07, Volume 7, p.10979, (2016) Read More / View Supplemental Materials
Abstract
Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia.Galinsky, KJ, Bhatia G., Loh PR, Georgiev S., Mukherjee S., Patterson NJ, and Price AL American journal of human genetics, 2016/03/03, Volume 98, Issue 3, p.456-72, (2016) Read More / View Supplemental Materials
Abstract
Integrative approaches for large-scale transcriptome-wide association studies.Gusev, A., Ko A., Shi H., Bhatia G., Chung W., Penninx BW, Jansen R., de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E., Alvarez M., Civelek M., Lusis AJ, Lehtimäki T., Raitoharju E., Kähönen M., Seppälä I., Raitakari OT, et al. Nature genetics, 2016/02/08, (2016) Read More / View Supplemental Materials
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2015
Abundant contribution of short tandem repeats to gene expression variation in humans.Gymrek, M., Willems T., Guilmatre A., Zeng H., Markus B., Georgiev S., Daly M. J., Price AL, Pritchard JK, Sharp AJ, and Erlich Y. Nature genetics, 2015/12/07, (2015) Read More / View Supplemental Materials
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Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.Palamara, PF, Francioli LC, Wilton PR, Genovese G., Gusev A., Finucane HK, Sankararaman S., Genome of the Netherlands Consortium, Sunyaev SR, de Bakker PI, Wakeley J., Pe'er I., and Price AL American journal of human genetics, 2015/11/11, (2015) Read More / View Supplemental Materials
Abstract
Two-Variance-Component Model Improves Genetic Prediction in Family Datasets.Tucker, G., Loh PR, MacLeod IM, Hayes BJ, Goddard ME, Berger B., and Price AL American journal of human genetics, 2015/11/05, Volume 97, Issue 5, p.677-90, (2015) Read More / View Supplemental Materials
Abstract
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.Loh, PR, Bhatia G., Gusev A., Finucane HK, Bulik-Sullivan BK, Pollack SJ, Schizophrenia Working Group of the Psychiatric Genomics Consortium, de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N., and Price AL Nature genetics, 2015/11/02, (2015) Read More / View Supplemental Materials
Abstract
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
Abstract
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.Vilhjálmsson, BJ, Yang J., Finucane HK, Gusev A., Lindström S., Ripke S., Genovese G., Loh PR, Bhatia G., Do R., Hayeck T., Won HH, and of in study Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery Biology Risk Inherited Variants Breast Cancer(DRIVE), Kathiresan S., Pato M., Pato C., Tamimi R., Stahl E., Zaitlen N., Pasaniuc B., et al. American journal of human genetics, 2015/10/01, Volume 97, Issue 4, p.576-92, (2015) Read More / View Supplemental Materials
Abstract
An atlas of genetic correlations across human diseases and traits.Bulik-Sullivan, B., Finucane HK, Anttila V., Gusev A., Day FR, Loh PR, ReproGen Consortium, Psychiatric Genomics Consortium, Genetic Consortium for Anorexia Nervosa of the Wellcome Trust Case Control Consortium 3, Duncan L., Perry JR, Patterson N., Robinson EB, Daly M. J., Price AL, and Neale BM Nature genetics, 2015/09/28, (2015) Read More / View Supplemental Materials
Abstract
Partitioning heritability by functional annotation using genome-wide association summary statistics.Finucane, HK, Bulik-Sullivan B., Gusev A., Trynka G., Reshef Y., Loh PR, Anttila V., Xu H., Zang C., Farh K., Ripke S., Day FR, ReproGen Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, RACI Consortium, Purcell S., Stahl E., Lindstrom S., Perry JR, Okada Y., et al. Nature genetics, 2015/09/28, (2015) Read More / View Supplemental Materials
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New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.Lee, SH, Byrne EM, Hultman CM, Kähler A., Vinkhuyzen AA, Ripke S., Andreassen OA, Frisell T., Gusev A., Hu X., Karlsson R., Mantzioris VX, McGrath JJ, Mehta D., Stahl EA, Zhao Q., Kendler KS, Sullivan PF, Price AL, O'Donovan M., et al. International journal of epidemiology, 2015/08/18, (2015) Read More / View Supplemental Materials
Abstract
Explicit Modeling of Ancestry Improves Polygenic Risk Scores and BLUP Prediction.Chen, CY, Han J., Hunter DJ, Kraft P., and Price AL Genetic epidemiology, 2015/05/21, (2015) Read More / View Supplemental Materials
Abstract
Mixed Model with Correction for Case-Control Ascertainment Increases Association Power.Hayeck, TJ, Zaitlen NA, Loh PR, Vilhjalmsson B., Pollack S., Gusev A., Yang J., Chen GB, Goddard ME, Visscher PM, Patterson N., and Price AL American journal of human genetics, 2015/04/14, (2015) Read More / View Supplemental Materials
Abstract
Efficient Bayesian mixed-model analysis increases association power in large cohorts.Loh, PR, Tucker G., Bulik-Sullivan BK, Vilhjálmsson BJ, Finucane HK, Salem RM, Chasman DI, Ridker PM, Neale BM, Berger B., Patterson N., and Price AL Nature genetics, 2015/02/02, (2015) Read More / View Supplemental Materials
Abstract
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.Bulik-Sullivan, BK, Loh PR, Finucane HK, Ripke S., Yang J., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson N., Daly M. J., Price AL, and Neale BM Nature genetics, 2015/02/02, (2015) Read More / View Supplemental Materials
Abstract
2014
Leveraging population admixture to characterize the heritability of complex traits.Zaitlen, N., Pasaniuc B., Sankararaman S., Bhatia G., Zhang J., Gusev A., Young T., Tandon A., Pollack S., Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S., Franceschini N., Goodman PG, He J., Hennis AJ, Hsing A., Ingles SA, et al. Nature genetics, 2014/11/10, (2014) Read More / View Supplemental Materials
Abstract
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.Gusev, A., Lee SH, Trynka G., Finucane H., Vilhjálmsson BJ, Xu H., Zang C., Ripke S., Bulik-Sullivan B., Stahl E., Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M., Pasaniuc B., Sullivan PF, Neale BM, et al. American journal of human genetics, 2014/11/06, Volume 95, Issue 5, p.535-52, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide Scan of 29,141 African Americans Finds No Evidence of Directional Selection since Admixture.Bhatia, G., Tandon A., Patterson N., Aldrich MC, Ambrosone CB, Amos C., Bandera EV, Berndt SI, Bernstein L., Blot WJ, Bock CH, Caporaso N., Casey G., Deming SL, Diver WR, Gapstur SM, Gillanders EM, Harris CC, Henderson BE, Ingles SA, et al. American journal of human genetics, 2014/09/17, (2014) Read More / View Supplemental Materials
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Fast and accurate imputation of summary statistics enhances evidence of functional enrichment.Pasaniuc, B., Zaitlen N., Shi H., Bhatia G., Gusev A., Pickrell J., Hirschhorn J., Strachan DP, Patterson N., and Price AL Bioinformatics (Oxford, England), 2014/07/01, (2014) Read More / View Supplemental Materials
Abstract
Advantages and pitfalls in the application of mixed-model association methods.Yang, J., Zaitlen NA, Goddard ME, Visscher PM, and Price AL Nature genetics, 2014/02/01, Volume 46, Issue 2, p.100-6, (2014) Read More / View Supplemental Materials
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2013
Quantifying Missing Heritability at Known GWAS Loci.Gusev, A., Bhatia G., Zaitlen N., Vilhjalmsson BJ, Diogo D., Stahl EA, Gregersen PK, Worthington J., Klareskog L., Raychaudhuri S., Plenge RM, Pasaniuc B., and Price AL PLoS genetics, 2013/12/01, Volume 9, Issue 12, p.e1003993, (2013) Read More / View Supplemental Materials
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Improved ancestry inference using weights from external reference panels.Chen, CY, Pollack S., Hunter DJ, Hirschhorn JN, Kraft P., and Price AL Bioinformatics (Oxford, England), 2013/04/30, (2013) Read More / View Supplemental Materials
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Response to sul and eskin.Price, AL, Zaitlen NA, Reich D., and Patterson N. Nature reviews. Genetics, 2013/04/01, Volume 14, Issue 4, p.300, (2013) Read More / View Supplemental Materials
Using population admixture to help complete maps of the human genome.Genovese, G., Handsaker RE, Li H., Altemose N., Lindgren AM, Chambert K., Pasaniuc B., Price AL, Reich D., Morton CC, Pollak MR, Wilson JG, and McCarroll SA Nature genetics, 2013/02/24, (2013) Read More / View Supplemental Materials
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2012
Informed conditioning on clinical covariates increases power in case-control association studies.Zaitlen, N., Lindström S., Pasaniuc B., Cornelis M., Genovese G., Pollack S., Barton A., Bickeböller H., Bowden DW, Eyre S., Freedman BI, Friedman DJ, Field JK, Groop L., Haugen A., Heinrich J., Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, et al. PLoS genetics, 2012/11/01, Volume 8, Issue 11, p.e1003032, (2012) Read More / View Supplemental Materials
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Reconstructing Native American population history.Reich, D., Patterson N., Campbell D., Tandon A., Mazieres S., Ray N., Parra MV, Rojas W., Duque C., Mesa N., García LF, Triana O., Blair S., Maestre A., Dib JC, Bravi CM, Bailliet G., Corach D., Hünemeier T., Bortolini MC, et al. Nature, 2012/07/11, (2012) Read More / View Supplemental Materials
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Exome sequencing and the genetic basis of complex traits.Kiezun, A., Garimella K., Do R., Stitziel NO, Neale BM, McLaren PJ, Gupta N., Sklar P., Sullivan PF, Moran JL, Hultman CM, Lichtenstein P., Magnusson P., Lehner T., Shugart YY, Price AL, de Bakker PI, Purcell SM, and Sunyaev SR Nature genetics, 2012/05/29, Volume 44, Issue 6, p.623-30, (2012) Read More / View Supplemental Materials
Extremely low-coverage sequencing and imputation increases power for genome-wide association studies.Pasaniuc, B., Rohland N., McLaren PJ, Garimella K., Zaitlen N., Li H., Gupta N., Neale BM, Daly M. J., Sklar P., Sullivan PF, Bergen S., Moran JL, Hultman CM, Lichtenstein P., Magnusson P., Purcell SM, Haas DW, Liang L., Sunyaev S., et al. Nature genetics, 2012/05/20, Volume 44, Issue 6, p.631-5, (2012) Read More / View Supplemental Materials
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2010
Integrating common and rare genetic variation in diverse human populations.International HapMap 3, Consortium, Altshuler DM, Gibbs RA, Peltonen L., Altshuler DM, Gibbs RA, Peltonen L., Dermitzakis E., Schaffner SF, Yu F., Peltonen L., Dermitzakis E., Bonnen PE, Altshuler DM, Gibbs RA, de Bakker PI, Deloukas P., Gabriel SB, Gwilliam R., Hunt S., et al. Nature, 2010/09/02, Volume 467, Issue 7311, p.52-8, (2010) Read More / View Supplemental Materials
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New approaches to population stratification in genome-wide association studies.Price, AL, Zaitlen NA, Reich D., and Patterson N. Nature reviews. Genetics, 2010/07/01, Volume 11, Issue 7, p.459-63, (2010) Read More / View Supplemental Materials
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2007
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.Plenge, RM, Cotsapas C., Davies L., Price AL, de Bakker PI, Maller J., Pe'er I., Burtt NP, Blumenstiel B., DeFelice M., Parkin M., Barry R., Winslow W., Healy C., Graham RR, Neale BM, Izmailova E., Roubenoff R., Parker AN, Glass R., et al. Nature genetics, 2007/12/01, Volume 39, Issue 12, p.1477-82, (2007) Read More / View Supplemental Materials
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2006
Population structure and eigenanalysis.Patterson, N., Price AL, and Reich D. PLoS genetics, 2006/12/01, Volume 2, Issue 12, p.e190, (2006) Read More / View Supplemental Materials
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  • Showing 1-36 of 36 Results