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  • Showing 1-17 of 17 Results
2015
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
2014
Genome-wide association study of kidney function decline in individuals of European descent.Gorski, M., Tin A., Garnaas M., McMahon GM, Chu AY, Tayo BO, Pattaro C., Teumer A., Chasman DI, Chalmers J., Hamet P., Tremblay J., Woodward M., Aspelund T., Eiriksdottir G., Gudnason V., Harris TB, Launer LJ, Smith AV, Mitchell BD, et al. Kidney international, 2014/12/10, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.and TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung Blood Institute, Crosby J., Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y., Tang ZZ, Zhang H., Hindy G., Masca N., Stirrups K., Kanoni S., Do R., Jun G., Hu Y., Kang HM, Xue C., Goel A., et al. The New England journal of medicine, 2014/07/03, Volume 371, Issue 1, p.22-31, (2014) Read More / View Supplemental Materials
Abstract
Predicting Stroke Through Genetic Risk Functions: The CHARGE Risk Score Project.Ibrahim-Verbaas, CA, Fornage M., Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M., Nalls M., Fontes JD, O'Donnell CJ, Kathiresan S., Ehret GB, Fox CS, Malik R., Dichgans M., Schmidt H., Lahti J., Heckbert SR, Lumley T., Rice K., et al. Stroke; a journal of cerebral circulation, 2014/01/16, (2014) Read More / View Supplemental Materials
Abstract
2013
2-Aminoadipic acid is a biomarker for diabetes risk.Wang, TJ, Ngo D., Psychogios N., Dejam A., Larson MG, Vasan RS, Ghorbani A., O'Sullivan J., Cheng S., Rhee EP, Sinha S., McCabe E., Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M., Pierce KA, Souza AL, Yu Y., et al. The Journal of clinical investigation, 2013/10/01, Volume 123, Issue 10, p.4309-17, (2013) Read More / View Supplemental Materials
Abstract
A combined epidemiologic and metabolomic approach improves CKD prediction.Rhee, EP, Clish CB, Ghorbani A., Larson MG, Elmariah S., McCabe E., Yang Q., Cheng S., Pierce K., Deik A., Souza AL, Farrell L., Domos C., Yeh RW, Palacios I., Rosenfield K., Vasan RS, Florez JC, Wang TJ, Fox CS, et al. Journal of the American Society of Nephrology : JASN, 2013/07/01, Volume 24, Issue 8, p.1330-8, (2013) Read More / View Supplemental Materials
Abstract
Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.de Miguel-Yanes, JM, Porneala B., Pencina MJ, Fox CS, Florez JC, Siscovick DS, Dupuis J., and Meigs JB Journal of hypertension, 2013/02/19, (2013) Read More / View Supplemental Materials
Abstract
2012
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.Manning, AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N., Chen H., Rybin D., Liu CT, Bielak LF, Prokopenko I., Amin N., Barnes D., Cadby G., Hottenga JJ, Ingelsson E., Jackson AU, Johnson T., Kanoni S., Ladenvall C., Lagou V., et al. Nature genetics, 2012/05/13, Volume 44, Issue 6, p.659-669, (2012) Read More / View Supplemental Materials
Abstract
Metabolite profiling identifies pathways associated with metabolic risk in humans.Cheng, S., Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D., Palma MJ, Roberts LD, Dejam A., Souza AL, Deik AA, Magnusson M., Fox CS, O'Donnell CJ, Vasan RS, Melander O., Clish CB, Gerszten RE, and Wang TJ Circulation, 2012/05/08, Volume 125, Issue 18, p.2222-31, (2012) Read More / View Supplemental Materials
Abstract
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.Saxena, R., Elbers CC, Guo Y., Peter I., Gaunt TR, Mega JL, Lanktree MB, Tare A., Castillo BA, Li YR, Johnson T., Bruinenberg M., Gilbert-Diamond D., Rajagopalan R., Voight BF, Balasubramanyam A., Barnard J., Bauer F., Baumert J., Bhangale T., et al. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.410-425, (2012) Read More / View Supplemental Materials
Abstract
2011
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.Rhee, EP, Cheng S., Larson MG, Walford GA, Lewis GD, McCabe E., Yang E., Farrell L., Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, and Gerszten RE The Journal of clinical investigation, 2011/04/01, Volume 121, Issue 4, p.1402-11, (2011) Read More / View Supplemental Materials
Abstract
Metabolite profiles and the risk of developing diabetes.Wang, TJ, Larson MG, Vasan RS, Cheng S., Rhee EP, McCabe E., Lewis GD, Fox CS, Jacques PF, Fernandez C., O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A., Melander O., Clish CB, and Gerszten RE Nature medicine, 2011/04/01, Volume 17, Issue 4, p.448-53, (2011) Read More / View Supplemental Materials
Abstract
2010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.Speliotes, EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G., Jackson AU, Allen HL, Lindgren CM, Luan J., Mägi R., Randall JC, Vedantam S., Winkler TW, Qi L., Workalemahu T., Heid IM, Steinthorsdottir V., Stringham HM, Weedon MN, Wheeler E., et al. Nature genetics, 2010/11/01, Volume 42, Issue 11, p.937-48, (2010) Read More / View Supplemental Materials
Abstract
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.Voight, BF, Scott LJ, Steinthorsdottir V., Morris AP, Dina C., Welch RP, Zeggini E., Huth C., Aulchenko YS, Thorleifsson G., McCulloch LJ, Ferreira T., Grallert H., Amin N., Wu G., Willer CJ, Raychaudhuri S., McCarroll SA, Langenberg C., Hofmann OM, et al. Nature genetics, 2010/07/01, Volume 42, Issue 7, p.579-89, (2010) Read More / View Supplemental Materials
Abstract
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.Saxena, R., Hivert MF, Langenberg C., Tanaka T., Pankow JS, Vollenweider P., Lyssenko V., Bouatia-Naji N., Dupuis J., Jackson AU, Kao WH, Li M., Glazer NL, Manning AK, Luan J., Stringham HM, Prokopenko I., Johnson T., Grarup N., Boesgaard TW, et al. Nature genetics, 2010/02/01, Volume 42, Issue 2, p.142-8, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-17 of 17 Results