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2016
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.Ehret, GB, Ferreira T., Chasman DI, Jackson AU, Schmidt EM, Johnson T., Thorleifsson G., Luan J., Donnelly LA, Kanoni S., Petersen AK, Pihur V., Strawbridge RJ, Shungin D., Hughes MF, Meirelles O., Kaakinen M., Bouatia-Naji N., Kristiansson K., Shah S., et al. Nature genetics, 2016/09/12, (2016) Read More / View Supplemental Materials
Abstract
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.Liu, C., Kraja AT, Smith JA, Brody JA, Franceschini N., Bis JC, Rice K., Morrison AC, Lu Y., Weiss S., Guo X., Palmas W., Martin LW, Chen YI, Surendran P., Drenos F., Cook JP, Auer PL, Chu AY, Giri A., et al. Nature genetics, 2016/09/12, (2016) Read More / View Supplemental Materials
Abstract
Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes.Harel, T., Yoon WH, Garone C., Gu S., Coban-Akdemir Z., Eldomery MK, Posey JE, Jhangiani SN, Rosenfeld JA, Cho MT, Fox S., Withers M., Brooks SM, Chiang T., Duraine L., Erdin S., Yuan B., Shao Y., Moussallem E., Lamperti C., et al. American journal of human genetics, 2016/09/07, (2016) Read More / View Supplemental Materials
Abstract
Whole Exome Sequencing in Atrial Fibrillation.Lubitz, SA, Brody JA, Bihlmeyer NA, Roselli C., Weng LC, Christophersen IE, Alonso A., Boerwinkle E., Gibbs RA, Bis JC, NHLBI GO Exome Sequencing Project, Cupples LA, Mohler PJ, Nickerson DA, Muzny D., Perez MV, Psaty BM, Soliman EZ, Sotoodehnia N., Lunetta KL, et al. PLoS genetics, 2016/09/01, Volume 12, Issue 9, p.e1006284, (2016) Read More / View Supplemental Materials
Abstract
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.Polfus, LM, Khajuria RK, Schick UM, Pankratz N., Pazoki R., Brody JA, Chen MH, Auer PL, Floyd JS, Huang J., Lange L., van Rooij FJ, Gibbs RA, Metcalf G., Muzny D., Veeraraghavan N., Walter K., Chen L., Yanek L., Becker LC, et al. American journal of human genetics, 2016/08/04, Volume 99, Issue 2, p.481-8, (2016) Read More / View Supplemental Materials
Abstract
An exome array study of the plasma metabolome.Rhee, EP, Yang Q., Yu B., Liu X., Cheng S., Deik A., Pierce KA, Bullock K., Ho JE, Levy D., Florez JC, Kathiresan S., Larson MG, Vasan RS, Clish CB, Wang TJ, Boerwinkle E., O'Donnell CJ, and Gerszten RE Nature communications, 2016/07/25, Volume 7, p.12360, (2016) Read More / View Supplemental Materials
Abstract
Association of Exome Sequences with Cardiovascular Traits among African Americans in the Jackson Heart Study.Peloso, GM, Lange LA, Varga TV, Nickerson DA, Smith JD, Griswold ME, Musani S., Polfus LM, Mei H., Gabriel S., Quarells RC, Altshuler D., Boerwinkle E., Daly M. J., Neale B., Correa A., Reiner AP, Wilson JG, and Kathiresan S. Circulation. Cardiovascular genetics, 2016/07/15, (2016) Read More / View Supplemental Materials
Abstract
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.Chami, N., Chen MH, Slater AJ, Eicher JD, Evangelou E., Tajuddin SM, Love-Gregory L., Kacprowski T., Schick UM, Nomura A., Giri A., Lessard S., Brody JA, Schurmann C., Pankratz N., Yanek LR, Manichaikul A., Pazoki R., Mihailov E., Hill WD, et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.Tajuddin, SM, Schick UM, Eicher JD, Chami N., Giri A., Brody JA, Hill WD, Kacprowski T., Li J., Lyytikäinen LP, Manichaikul A., Mihailov E., O'Donoghue ML, Pankratz N., Pazoki R., Polfus LM, Smith AV, Schurmann C., Vacchi-Suzzi C., Waterworth DM, et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.Eicher, JD, Chami N., Kacprowski T., Nomura A., Chen MH, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N., Polfus L., Schurmann C., Giri A., Brody JA, Lange LA, Manichaikul A., Hill WD, Pazoki R., Elliot P., Evangelou E., et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Trans-ethnic Meta-Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.Liu, CT, Raghavan S., Maruthur N., Kabagambe EK, Hong J., Ng MC, Hivert MF, Lu Y., An P., Bentley AR, Drolet AM, Gaulton KJ, Guo X., Armstrong LL, Irvin MR, Li M., Lipovich L., Rybin DV, Taylor KD, Agyemang C., et al. American journal of human genetics, 2016/06/15, (2016) Read More / View Supplemental Materials
Abstract
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.Scott, RA, Freitag DF, Li L., Chu AY, Surendran P., Young R., Grarup N., Stancáková A., Chen Y., Varga TV, Yaghootkar H., Luan J., Zhao JH, Willems SM, Wessel J., Wang S., Maruthur N., Michailidou K., Pirie A., van der Lee SJ, et al. Science translational medicine, 2016/06/01, Volume 8, Issue 341, p.341ra76, (2016) Read More / View Supplemental Materials
Abstract
An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group.Sung, YJ, Winkler TW, Manning AK, Aschard H., Gudnason V., Harris TB, Smith AV, Boerwinkle E., Brown MR, Morrison AC, Fornage M., Lin LA, Richard M., Bartz TM, Psaty BM, Hayward C., Polasek O., Marten J., Rudan I., Feitosa MF, et al. Genetic epidemiology, 2016/05/27, (2016) Read More / View Supplemental Materials
Abstract
Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure.Smith, JG, Felix JF, Morrison AC, Kalogeropoulos A., Trompet S., Wilk JB, Gidlöf O., Wang X., Morley M., Mendelson M., Joehanes R., Ligthart S., Shan X., Bis JC, Wang YA, Sjögren M., Ngwa J., Brandimarto J., Stott DJ, Aguilar D., et al. PLoS genetics, 2016/05/01, Volume 12, Issue 5, p.e1006034, (2016) Read More / View Supplemental Materials
Abstract
Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia.Khera, AV, Won HH, Peloso GM, Lawson KS, Bartz TM, Deng X., van Leeuwen EM, Natarajan P., Emdin CA, Bick AG, Morrison AC, Brody JA, Gupta N., Nomura A., Kessler T., Duga S., Bis JC, van Duijn CM, Cupples LA, Psaty B., et al. Journal of the American College of Cardiology, 2016/03/28, (2016) Read More / View Supplemental Materials
Abstract
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Pattaro, C., Teumer A., Gorski M., Chu AY, Li M., Mijatovic V., Garnaas M., Tin A., Sorice R., Li Y., Taliun D., Olden M., Foster M., Yang Q., Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C., Tayo B., et al. Nature communications, 2016/01/21, Volume 7, p.10023, (2016) Read More / View Supplemental Materials
Abstract
2015
Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk.Yu, B., Pulit SL, Hwang SJ, Brody JA, Amin N., Auer PL, Bis JC, Boerwinkle E., Burke GL, Chakravarti A., Correa A., Dreisbach AW, Franco OH, Ehret GB, Franceschini N., Hofman A., Lin DY, Metcalf GA, Musani SK, Muzny D., et al. Circulation. Cardiovascular genetics, 2015/12/11, (2015) Read More / View Supplemental Materials
Abstract
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Gaulton, KJ, Ferreira T., Lee Y., Raimondo A., Mägi R., Reschen ME, Mahajan A., Locke A., William Rayner N., Robertson N., Scott RA, Prokopenko I., Scott LJ, Green T., Sparso T., Thuillier D., Yengo L., Grallert H., Wahl S., Frånberg M., et al. Nature genetics, 2015/11/09, (2015) Read More / View Supplemental Materials
Abstract
Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.Karaca, E., Harel T., Pehlivan D., Jhangiani SN, Gambin T., Coban Akdemir Z., Gonzaga-Jauregui C., Erdin S., Bayram Y., Campbell IM, Hunter JV, Atik MM, Van Esch H., Yuan B., Wiszniewski W., Isikay S., Yesil G., Yuregir OO, Tug Bozdogan S., Aslan H., et al. Neuron, 2015/11/04, Volume 88, Issue 3, p.499-513, (2015) Read More / View Supplemental Materials
Abstract
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
Abstract
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.Winkler, TW, Justice AE, Graff M., Barata L., Feitosa MF, Chu S., Czajkowski J., Esko T., Fall T., Kilpeläinen TO, Lu Y., Mägi R., Mihailov E., Pers TH, Rüeger S., Teumer A., Ehret GB, Ferreira T., Heard-Costa NL, Karjalainen J., et al. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005378, (2015) Read More / View Supplemental Materials
Abstract
Rare coding variants and X-linked loci associated with age at menarche.Lunetta, KL, Day FR, Sulem P., Ruth KS, Tung JY, Hinds DA, Esko T., Elks CE, Altmaier E., He C., Huffman JE, Mihailov E., Porcu E., Robino A., Rose LM, Schick UM, Stolk L., Teumer A., Thompson DJ, Traglia M., et al. Nature communications, 2015/08/04, Volume 6, p.7756, (2015) Read More / View Supplemental Materials
Abstract
Directional dominance on stature and cognition in diverse human populations.Joshi, PK, Esko T., Mattsson H., Eklund N., Gandin I., Nutile T., Jackson AU, Schurmann C., Smith AV, Zhang W., Okada Y., Stančáková A., Faul JD, Zhao W., Bartz TM, Concas MP, Franceschini N., Enroth S., Vitart V., Trompet S., et al. Nature, 2015/07/01, (2015) Read More / View Supplemental Materials
Abstract
Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.Jansen, H., Loley C., Lieb W., Pencina MJ, Nelson CP, Kathiresan S., Peloso GM, Voight BF, Reilly MP, Assimes TL, Boerwinkle E., Hengstenberg C., Laaksonen R., McPherson R., Roberts R., Thorsteinsdottir U., Peters A., Gieger C., Rawal R., Thompson JR, et al. Atherosclerosis, 2015/06/03, Volume 241, Issue 2, p.419-426, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949).Davies, G., Armstrong N., Bis JC, Bressler J., Chouraki V., Giddaluru S., Hofer E., Ibrahim-Verbaas CA, Kirin M., Lahti J., van der Lee SJ, Le Hellard S., Liu T., Marioni RE, Oldmeadow C., Postmus I., Smith AV, Smith JA, Thalamuthu A., Thomson R., et al. Molecular psychiatry, 2015/02/03, (2015) Read More / View Supplemental Materials
Abstract
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.Wessel, J., Chu AY, Willems SM, Wang S., Yaghootkar H., Brody JA, Dauriz M., Hivert MF, Raghavan S., Lipovich L., Hidalgo B., Fox K., Huffman JE, An P., Lu Y., Rasmussen-Torvik LJ, Grarup N., Ehm MG, Li L., Baldridge AS, et al. Nature communications, 2015/01/29, Volume 6, p.5897, (2015) Read More / View Supplemental Materials
Abstract
Genetic Overlap Between Diagnostic Subtypes of Ischemic Stroke.Holliday, EG, Traylor M., Malik R., Bevan S., Falcone G., Hopewell JC, Cheng YC, Cotlarciuc I., Bis JC, Boerwinkle E., Boncoraglio GB, Clarke R., Cole JW, Fornage M., Furie KL, Ikram MA, Jannes J., Kittner SJ, Lincz LF, Maguire JM, et al. Stroke; a journal of cerebral circulation, 2015/01/22, (2015) Read More / View Supplemental Materials
Abstract
2014
Association of Sickle Cell Trait With Chronic Kidney Disease and Albuminuria in African Americans.Naik, RP, Derebail VK, Grams ME, Franceschini N., Auer PL, Peloso GM, Young BA, Lettre G., Peralta CA, Katz R., Hyacinth HI, Quarells RC, Grove ML, Bick AG, Fontanillas P., Rich SS, Smith JD, Boerwinkle E., Rosamond WD, Ito K., et al. JAMA, 2014/11/26, Volume 312, Issue 20, p.2115-2125, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
Association of exome sequences with plasma C-reactive protein levels in >9000 participants.Schick, UM, Auer PL, Bis JC, Lin H., Wei P., Pankratz N., Lange LA, Brody J., Stitziel NO, Kim DS, Carlson CS, Fornage M., Haessler J., Hsu L., Jackson RD, Kooperberg C., Leal SM, Psaty BM, Boerwinkle E., Tracy R., et al. Human molecular genetics, 2014/09/03, (2014) Read More / View Supplemental Materials
Abstract
A framework for the interpretation of de novo mutation in human disease.Samocha, KE, Robinson EB, Sanders SJ, Stevens C., Sabo A., McGrath LM, Kosmicki JA, Rehnström K., Mallick S., Kirby A., Wall DP, Macarthur DG, Gabriel SB, DePristo M., Purcell SM, Palotie A., Boerwinkle E., Buxbaum JD, Cook EH Jr, Gibbs RA, et al. Nature genetics, 2014/08/03, (2014) Read More / View Supplemental Materials
Abstract
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.Perry, JR, Day F., Elks CE, Sulem P., Thompson DJ, Ferreira T., He C., Chasman DI, Esko T., Thorleifsson G., Albrecht E., Ang WQ, Corre T., Cousminer DL, Feenstra B., Franceschini N., Ganna A., Johnson AD, Kjellqvist S., Lunetta KL, et al. Nature, 2014/07/23, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.Du, M., Auer PL, Jiao S., Haessler J., Altshuler D., Boerwinkle E., Carlson CS, Carty CL, Chen YD, Curtis K., Franceschini N., Hsu L., Jackson R., Lange LA, Lettre G., Monda KL, and National Heart, Lung Blood Institute(NHLBI) GO Exome Sequencing Project, Nickerson DA, Reiner AP, Rich SS, et al. Human molecular genetics, 2014/07/15, (2014) Read More / View Supplemental Materials
Abstract
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.and TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung Blood Institute, Crosby J., Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y., Tang ZZ, Zhang H., Hindy G., Masca N., Stirrups K., Kanoni S., Do R., Jun G., Hu Y., Kang HM, Xue C., Goel A., et al. The New England journal of medicine, 2014/07/03, Volume 371, Issue 1, p.22-31, (2014) Read More / View Supplemental Materials
Abstract
Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index.Hoggart, CJ, Venturini G., Mangino M., Gomez F., Ascari G., Zhao JH, Teumer A., Winkler TW, Tšernikova N., Luan J., Mihailov E., Ehret GB, Zhang W., Lamparter D., Esko T., Macé A., Rüeger S., Bochud PY, Barcella M., Dauvilliers Y., et al. PLoS genetics, 2014/07/01, Volume 10, Issue 7, p.e1004508, (2014) Read More / View Supplemental Materials
Abstract
Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci.Tragante, V., Barnes MR, Ganesh SK, Lanktree MB, Guo W., Franceschini N., Smith EN, Johnson T., Holmes MV, Padmanabhan S., Karczewski KJ, Almoguera B., Barnard J., Baumert J., Chang YP, Elbers CC, Farrall M., Fischer ME, Gaunt TR, Gho JM, et al. American journal of human genetics, 2014/02/19, (2014) Read More / View Supplemental Materials
Abstract
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.Peloso, GM, Auer PL, Bis JC, Voorman A., Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M., Isaacs A., Jakobsdottir J., Feitosa MF, Davies G., Huffman JE, Manichaikul A., Davis B., Lohman K., Joon AY, Smith AV, et al. American journal of human genetics, 2014/02/06, Volume 94, Issue 2, p.223-32, (2014) Read More / View Supplemental Materials
Abstract
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol.Lange, LA, Hu Y., Zhang H., Xue C., Schmidt EM, Tang ZZ, Bizon C., Lange EM, Smith JD, Turner EH, Jun G., Kang HM, Peloso G., Auer P., Li KP, Flannick J., Zhang J., Fuchsberger C., Gaulton K., Lindgren C., et al. American journal of human genetics, 2014/02/06, Volume 94, Issue 2, p.233-45, (2014) Read More / View Supplemental Materials
Abstract
Predicting Stroke Through Genetic Risk Functions: The CHARGE Risk Score Project.Ibrahim-Verbaas, CA, Fornage M., Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M., Nalls M., Fontes JD, O'Donnell CJ, Kathiresan S., Ehret GB, Fox CS, Malik R., Dichgans M., Schmidt H., Lahti J., Heckbert SR, Lumley T., Rice K., et al. Stroke; a journal of cerebral circulation, 2014/01/16, (2014) Read More / View Supplemental Materials
Abstract
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.Escott-Price, V., Bellenguez C., Wang LS, Choi SH, Harold D., Jones L., Holmans P., Gerrish A., Vedernikov A., Richards A., Destefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R., Jun G., Bis JC, Beecham GW, Grenier-Boley B., Russo G., et al. PloS one, 2014/01/01, Volume 9, Issue 6, p.e94661, (2014) Read More / View Supplemental Materials
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2013
Common variants associated with plasma triglycerides and risk for coronary artery disease.Do, R., Willer CJ, Schmidt EM, Sengupta S., Gao C., Peloso GM, Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich ML, Mora S., Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A., Den Hertog HM, Donnelly LA, Ehret GB, Esko T., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1345-52, (2013) Read More / View Supplemental Materials
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Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.Lim, ET, Raychaudhuri S., Sanders SJ, Stevens C., Sabo A., Macarthur DG, Neale BM, Kirby A., Ruderfer DM, Fromer M., Lek M., Liu L., Flannick J., Ripke S., Nagaswamy U., Muzny D., Reid JG, Hawes A., Newsham I., Wu Y., et al. Neuron, 2013/01/23, Volume 77, Issue 2, p.235-42, (2013) Read More / View Supplemental Materials
Abstract
2012
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.Voight, BF, Peloso GM, Orho-Melander M., Frikke-Schmidt R., Barbalic M., Jensen MK, Hindy G., Hólm H., Ding EL, Johnson T., Schunkert H., Samani NJ, Clarke R., Hopewell JC, Thompson JF, Li M., Thorleifsson G., Newton-Cheh C., Musunuru K., Pirruccello JP, et al. Lancet, 2012/05/17, (2012) Read More / View Supplemental Materials
Abstract
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.Manning, AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N., Chen H., Rybin D., Liu CT, Bielak LF, Prokopenko I., Amin N., Barnes D., Cadby G., Hottenga JJ, Ingelsson E., Jackson AU, Johnson T., Kanoni S., Ladenvall C., Lagou V., et al. Nature genetics, 2012/05/13, Volume 44, Issue 6, p.659-669, (2012) Read More / View Supplemental Materials
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Patterns and rates of exonic de novo mutations in autism spectrum disorders.Neale, BM, Kou Y., Liu L., Ma'ayan A., Samocha KE, Sabo A., Lin CF, Stevens C., Wang LS, Makarov V., Polak P., Yoon S., Maguire J., Crawford EL, Campbell NG, Geller ET, Valladares O., Schafer C., Liu H., Zhao T., et al. Nature, 2012/04/04, (2012) Read More / View Supplemental Materials
Abstract
Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project.Musunuru, K., Romaine SP, Lettre G., Wilson JG, Volcik KA, Tsai MY, Taylor HA Jr, Schreiner PJ, Rotter JI, Rich SS, Redline S., Psaty BM, Papanicolaou GJ, Ordovas JM, Liu K., Krauss RM, Glazer NL, Gabriel SB, Fornage M., Cupples LA, et al. PloS one, 2012/01/01, Volume 7, Issue 5, p.e36473, (2012) Read More / View Supplemental Materials
Abstract
2010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.Speliotes, EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G., Jackson AU, Allen HL, Lindgren CM, Luan J., Mägi R., Randall JC, Vedantam S., Winkler TW, Qi L., Workalemahu T., Heid IM, Steinthorsdottir V., Stringham HM, Weedon MN, Wheeler E., et al. Nature genetics, 2010/11/01, Volume 42, Issue 11, p.937-48, (2010) Read More / View Supplemental Materials
Abstract
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.Voight, BF, Scott LJ, Steinthorsdottir V., Morris AP, Dina C., Welch RP, Zeggini E., Huth C., Aulchenko YS, Thorleifsson G., McCulloch LJ, Ferreira T., Grallert H., Amin N., Wu G., Willer CJ, Raychaudhuri S., McCarroll SA, Langenberg C., Hofmann OM, et al. Nature genetics, 2010/07/01, Volume 42, Issue 7, p.579-89, (2010) Read More / View Supplemental Materials
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Candidate gene association resource (CARe): design, methods, and proof of concept.Musunuru, K., Lettre G., Young T., Farlow DN, Pirruccello JP, Ejebe KG, Keating BJ, Yang Q., Chen MH, Lapchyk N., Crenshaw A., Ziaugra L., Rachupka A., Benjamin EJ, Cupples LA, Fornage M., Fox ER, Heckbert SR, Hirschhorn JN, Newton-Cheh C., et al. Circulation. Cardiovascular genetics, 2010/06/01, Volume 3, Issue 3, p.267-75, (2010) Read More / View Supplemental Materials
Abstract
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.Saxena, R., Hivert MF, Langenberg C., Tanaka T., Pankow JS, Vollenweider P., Lyssenko V., Bouatia-Naji N., Dupuis J., Jackson AU, Kao WH, Li M., Glazer NL, Manning AK, Luan J., Stringham HM, Prokopenko I., Johnson T., Grarup N., Boesgaard TW, et al. Nature genetics, 2010/02/01, Volume 42, Issue 2, p.142-8, (2010) Read More / View Supplemental Materials
Abstract
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