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2016
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.Chami, N., Chen MH, Slater AJ, Eicher JD, Evangelou E., Tajuddin SM, Love-Gregory L., Kacprowski T., Schick UM, Nomura A., Giri A., Lessard S., Brody JA, Schurmann C., Pankratz N., Yanek LR, Manichaikul A., Pazoki R., Mihailov E., Hill WD, et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.Tajuddin, SM, Schick UM, Eicher JD, Chami N., Giri A., Brody JA, Hill WD, Kacprowski T., Li J., Lyytikäinen LP, Manichaikul A., Mihailov E., O'Donoghue ML, Pankratz N., Pazoki R., Polfus LM, Smith AV, Schurmann C., Vacchi-Suzzi C., Waterworth DM, et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.Eicher, JD, Chami N., Kacprowski T., Nomura A., Chen MH, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N., Polfus L., Schurmann C., Giri A., Brody JA, Lange LA, Manichaikul A., Hill WD, Pazoki R., Elliot P., Evangelou E., et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.Gormley, P., Anttila V., Winsvold BS, Palta P., Esko T., Pers TH, Farh KH, Cuenca-Leon E., Muona M., Furlotte NA, Kurth T., Ingason A., McMahon G., Ligthart L., Terwindt GM, Kallela M., Freilinger TM, Ran C., Gordon SG, Stam AH, et al. Nature genetics, 2016/06/20, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide association study identifies 74 loci associated with educational attainment.Okbay, A., Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P., Chen GB, Emilsson V., Meddens SF, Oskarsson S., Pickrell JK, Thom K., Timshel P., de Vlaming R., Abdellaoui A., Ahluwalia TS, Bacelis J., Baumbach C., Bjornsdottir G., et al. Nature, 2016/05/11, Volume 533, Issue 7604, p.539-42, (2016) Read More / View Supplemental Materials
Abstract
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.Okbay, A., Baselmans BM, De Neve JE, Turley P., Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J., Gratten J., Lee JJ, Liu JZ, de Vlaming R., Ahluwalia TS, Buchwald J., Cavadino A., Frazier-Wood AC, Furlotte NA, Garfield V., et al. Nature genetics, 2016/04/18, (2016) Read More / View Supplemental Materials
Abstract
Twenty-eight genetic loci associated with ST-T wave amplitudes of the electrocardiogram.Verweij, N., Mateo Leach I., Isaacs A., Arking DE, Bis JC, Pers TH, van den Berg ME, Lyytikäinen LP, Barnett P., Wang X., study LifeLines Cohort, Soliman EZ, van Duijn CM, Kähönen M., van Veldhuisen DJ, Kors JA, Raitakari OT, Silva CT, Lehtimäki T., Hillege HL, et al. Human molecular genetics, 2016/03/08, (2016) Read More / View Supplemental Materials
Abstract
Integrative approaches for large-scale transcriptome-wide association studies.Gusev, A., Ko A., Shi H., Bhatia G., Chung W., Penninx BW, Jansen R., de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E., Alvarez M., Civelek M., Lusis AJ, Lehtimäki T., Raitoharju E., Kähönen M., Seppälä I., Raitakari OT, et al. Nature genetics, 2016/02/08, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.Kilpeläinen, TO, Carli JF, Skowronski AA, Sun Q., Kriebel J., Feitosa MF, Hedman Å. K., Drong AW, Hayes JE, Zhao J., Pers TH, Schick U., Grarup N., Kutalik Z., Trompet S., Mangino M., Kristiansson K., Beekman M., Lyytikäinen LP, Eriksson J., et al. Nature communications, 2016/02/01, Volume 7, p.10494, (2016) Read More / View Supplemental Materials
Abstract
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.Lu, Y., Day FR, Gustafsson S., Buchkovich ML, Na J., Bataille V., Cousminer DL, Dastani Z., Drong AW, Esko T., Evans DM, Falchi M., Feitosa MF, Ferreira T., Hedman Å. K., Haring R., Hysi PG, Iles MM, Justice AE, Kanoni S., et al. Nature communications, 2016/02/01, Volume 7, p.10495, (2016) Read More / View Supplemental Materials
Abstract
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Pattaro, C., Teumer A., Gorski M., Chu AY, Li M., Mijatovic V., Garnaas M., Tin A., Sorice R., Li Y., Taliun D., Olden M., Foster M., Yang Q., Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C., Tayo B., et al. Nature communications, 2016/01/21, Volume 7, p.10023, (2016) Read More / View Supplemental Materials
Abstract
2015
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.Felix, JF, Bradfield JP, Monnereau C., van der Valk RJ, Stergiakouli E., Chesi A., Gaillard R., Feenstra B., Thiering E., Kreiner-Møller E., Mahajan A., Pitkänen N., Joro R., Cavadino A., Huikari V., Franks S., Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
Abstract
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.Winkler, TW, Justice AE, Graff M., Barata L., Feitosa MF, Chu S., Czajkowski J., Esko T., Fall T., Kilpeläinen TO, Lu Y., Mägi R., Mihailov E., Pers TH, Rüeger S., Teumer A., Ehret GB, Ferreira T., Heard-Costa NL, Karjalainen J., et al. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005378, (2015) Read More / View Supplemental Materials
Abstract
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.Kato, N., Loh M., Takeuchi F., Verweij N., Wang X., Zhang W., Kelly TN, Saleheen D., Lehne B., Leach IM, Drong AW, Abbott J., Wahl S., Tan ST, Scott WR, Campanella G., Chadeau-Hyam M., Afzal U., Ahluwalia TS, Bonder MJ, et al. Nature genetics, 2015/09/21, (2015) Read More / View Supplemental Materials
Abstract
Directional dominance on stature and cognition in diverse human populations.Joshi, PK, Esko T., Mattsson H., Eklund N., Gandin I., Nutile T., Jackson AU, Schurmann C., Smith AV, Zhang W., Okada Y., Stančáková A., Faul JD, Zhao W., Bartz TM, Concas MP, Franceschini N., Enroth S., Vitart V., Trompet S., et al. Nature, 2015/07/01, (2015) Read More / View Supplemental Materials
Abstract
The impact of low-frequency and rare variants on lipid levels.Surakka, I., Horikoshi M., Mägi R., Sarin AP, Mahajan A., Lagou V., Marullo L., Ferreira T., Miraglio B., Timonen S., Kettunen J., Pirinen M., Karjalainen J., Thorleifsson G., Hägg S., Hottenga JJ, Isaacs A., Ladenvall C., Beekman M., Esko T., et al. Nature genetics, 2015/05/11, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
Metabolite Profiling and Cardiovascular Event Risk: A Prospective Study of Three Population-Based Cohorts.Würtz, P., Havulinna AS, Soininen P., Tynkkynen T., Prieto-Merino D., Tillin T., Ghorbani A., Artati A., Wang Q., Tiainen M., Kangas AJ, Kettunen J., Kaikkonen J., Mikkilä V., Jula A., Kähönen M., Lehtimäki T., Lawlor DA, Gaunt TR, Hughes AD, et al. Circulation, 2015/01/08, (2015) Read More / View Supplemental Materials
Abstract
2014
Genome-wide association study of kidney function decline in individuals of European descent.Gorski, M., Tin A., Garnaas M., McMahon GM, Chu AY, Tayo BO, Pattaro C., Teumer A., Chasman DI, Chalmers J., Hamet P., Tremblay J., Woodward M., Aspelund T., Eiriksdottir G., Gudnason V., Harris TB, Launer LJ, Smith AV, Mitchell BD, et al. Kidney international, 2014/12/10, (2014) Read More / View Supplemental Materials
Abstract
Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study.Gottlieb, DJ, Hek K., Chen TH, Watson NF, Eiriksdottir G., Byrne EM, Cornelis M., Warby SC, Bandinelli S., Cherkas L., Evans DS, Grabe HJ, Lahti J., Li M., Lehtimäki T., Lumley T., Marciante KD, Pérusse L., Psaty BM, Robbins J., et al. Molecular psychiatry, 2014/12/02, (2014) Read More / View Supplemental Materials
Abstract
Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study.Gottlieb, DJ, Hek K., Chen TH, Watson NF, Eiriksdottir G., Byrne EM, Cornelis M., Warby SC, Bandinelli S., Cherkas L., Evans DS, Grabe HJ, Lahti J., Li M., Lehtimäki T., Lumley T., Marciante KD, Pérusse L., Psaty BM, Robbins J., et al. Molecular psychiatry, 2014/11/18, (2014) Read More / View Supplemental Materials
Synaptic, transcriptional and chromatin genes disrupted in autism.De Rubeis, S., He X., Goldberg AP, Poultney CS, Samocha K., Ercument Cicek A., Kou Y., Liu L., Fromer M., Walker S., Singh T., Klei L., Kosmicki J., Fu SC, Aleksic B., Biscaldi M., Bolton PF, Brownfeld JM, Cai J., Campbell NG, et al. Nature, 2014/11/13, Volume 515, Issue 7526, p.209-15, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.The Coffee and Caffeine Genetics, Consortium, Cornelis MC, Byrne EM, Esko T., Nalls MA, Ganna A., Paynter N., Monda KL, Amin N., Fischer K., Renstrom F., Ngwa JS, Huikari V., Cavadino A., Nolte IM, Teumer A., Yu K., Marques-Vidal P., Rawal R., Manichaikul A., et al. Molecular psychiatry, 2014/10/07, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population.Lim, ET, Würtz P., Havulinna AS, Palta P., Tukiainen T., Rehnström K., Esko T., Mägi R., Inouye M., Lappalainen T., Chan Y., Salem RM, Lek M., Flannick J., Sim X., Manning A., Ladenvall C., Bumpstead S., Hämäläinen E., Aalto K., et al. PLoS genetics, 2014/07/01, Volume 10, Issue 7, p.e1004494, (2014) Read More / View Supplemental Materials
Abstract
A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach.Traylor, M., Mäkelä KM, Kilarski LL, Holliday EG, Devan WJ, Nalls MA, Wiggins KL, Zhao W., Cheng YC, Achterberg S., Malik R., Sudlow C., Bevan S., Raitoharju E., METASTROKE, International Stroke Genetics Consortium Wellcome Trust Case Consortium(WTCCC2) 2, Oksala N., Thijs V., Lemmens R., Lindgren A., Slowik A., et al. PLoS genetics, 2014/07/01, Volume 10, Issue 7, p.e1004469, (2014) Read More / View Supplemental Materials
Abstract
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.Vimaleswaran, KS, Cavadino A., Berry DJ, investigators LifeLines Cohort Study, Jorde R., Dieffenbach AK, Lu C., Alves AC, Heerspink HJ, Tikkanen E., Eriksson J., Wong A., Mangino M., Jablonski KA, Nolte IM, Houston DK, Ahluwalia TS, van der Most PJ, Pasko D., Zgaga L., et al. The lancet. Diabetes & endocrinology, 2014/06/25, (2014) Read More / View Supplemental Materials
Abstract
Chromosome x-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation.Tukiainen, T., Pirinen M., Sarin AP, Ladenvall C., Kettunen J., Lehtimäki T., Lokki ML, Perola M., Sinisalo J., Vlachopoulou E., Eriksson JG, Groop L., Jula A., Järvelin MR, Raitakari OT, Salomaa V., and Ripatti S. PLoS genetics, 2014/02/01, Volume 10, Issue 2, p.e1004127, (2014) Read More / View Supplemental Materials
Abstract
Common Variation in Fatty Acid Metabolic Genes and Risk of Incident Sudden Cardiac Arrest.Lemaitre, RN, Johnson CO, Hesselson S., Sotoodhenia N., McKnight B., Sitlani CM, Rea TD, King IB, Kwok PY, Mak A., Li G., Brody J., Larson E., Mozaffarian D., Psaty BM, Huertas-Vazquez A., Tardif JC, Albert CM, Lyytikäinen LP, Arking DE, et al. Heart rhythm : the official journal of the Heart Rhythm Society, 2014/01/10, (2014) Read More / View Supplemental Materials
Abstract
High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms.Kurki, MI, Gaál EI, Kettunen J., Lappalainen T., Menelaou A., Anttila V., van 't Hof FN, von Und Zu Fraunberg M., Helisalmi S., Hiltunen M., Lehto H., Laakso A., Kivisaari R., Koivisto T., Ronkainen A., Rinne J., Kiemeney LA, Vermeulen SH, Kaunisto MA, Eriksson JG, et al. PLoS genetics, 2014/01/01, Volume 10, Issue 1, p.e1004134, (2014) Read More / View Supplemental Materials
Abstract
2013
Common variants associated with plasma triglycerides and risk for coronary artery disease.Do, R., Willer CJ, Schmidt EM, Sengupta S., Gao C., Peloso GM, Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich ML, Mora S., Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A., Den Hertog HM, Donnelly LA, Ehret GB, Esko T., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1345-52, (2013) Read More / View Supplemental Materials
Abstract
2010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.Speliotes, EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G., Jackson AU, Allen HL, Lindgren CM, Luan J., Mägi R., Randall JC, Vedantam S., Winkler TW, Qi L., Workalemahu T., Heid IM, Steinthorsdottir V., Stringham HM, Weedon MN, Wheeler E., et al. Nature genetics, 2010/11/01, Volume 42, Issue 11, p.937-48, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-33 of 33 Results