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2016
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.Kilpeläinen, TO, Carli JF, Skowronski AA, Sun Q., Kriebel J., Feitosa MF, Hedman Å. K., Drong AW, Hayes JE, Zhao J., Pers TH, Schick U., Grarup N., Kutalik Z., Trompet S., Mangino M., Kristiansson K., Beekman M., Lyytikäinen LP, Eriksson J., et al. Nature communications, 2016/02/01, Volume 7, p.10494, (2016) Read More / View Supplemental Materials
Abstract
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Pattaro, C., Teumer A., Gorski M., Chu AY, Li M., Mijatovic V., Garnaas M., Tin A., Sorice R., Li Y., Taliun D., Olden M., Foster M., Yang Q., Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C., Tayo B., et al. Nature communications, 2016/01/21, Volume 7, p.10023, (2016) Read More / View Supplemental Materials
Abstract
2015
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
Abstract
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.Winkler, TW, Justice AE, Graff M., Barata L., Feitosa MF, Chu S., Czajkowski J., Esko T., Fall T., Kilpeläinen TO, Lu Y., Mägi R., Mihailov E., Pers TH, Rüeger S., Teumer A., Ehret GB, Ferreira T., Heard-Costa NL, Karjalainen J., et al. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005378, (2015) Read More / View Supplemental Materials
Abstract
Population genetic differentiation of height and body mass index across Europe.Robinson, MR, Hemani G., Medina-Gomez C., Mezzavilla M., Esko T., Shakhbazov K., Powell JE, Vinkhuyzen A., Berndt SI, Gustafsson S., Justice AE, Kahali B., Locke AE, Pers TH, Vedantam S., Wood AR, van Rheenen W., Andreassen OA, Gasparini P., Metspalu A., et al. Nature genetics, 2015/09/14, (2015) Read More / View Supplemental Materials
Abstract
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.Zheng, HF, Forgetta V., Hsu YH, Estrada K., Rosello-Diez A., Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C., Kleinman A., Styrkarsdottir U., Liu CT, Uggla C., Evans DS, Nielson CM, Walter K., Pettersson-Kymmer U., McCarthy S., Eriksson J., et al. Nature, 2015/09/14, (2015) Read More / View Supplemental Materials
Abstract
Rare coding variants and X-linked loci associated with age at menarche.Lunetta, KL, Day FR, Sulem P., Ruth KS, Tung JY, Hinds DA, Esko T., Elks CE, Altmaier E., He C., Huffman JE, Mihailov E., Porcu E., Robino A., Rose LM, Schick UM, Stolk L., Teumer A., Thompson DJ, Traglia M., et al. Nature communications, 2015/08/04, Volume 6, p.7756, (2015) Read More / View Supplemental Materials
Abstract
Directional dominance on stature and cognition in diverse human populations.Joshi, PK, Esko T., Mattsson H., Eklund N., Gandin I., Nutile T., Jackson AU, Schurmann C., Smith AV, Zhang W., Okada Y., Stančáková A., Faul JD, Zhao W., Bartz TM, Concas MP, Franceschini N., Enroth S., Vitart V., Trompet S., et al. Nature, 2015/07/01, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
Efficient Bayesian mixed-model analysis increases association power in large cohorts.Loh, PR, Tucker G., Bulik-Sullivan BK, Vilhjálmsson BJ, Finucane HK, Salem RM, Chasman DI, Ridker PM, Neale BM, Berger B., Patterson N., and Price AL Nature genetics, 2015/02/02, (2015) Read More / View Supplemental Materials
Abstract
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.Wessel, J., Chu AY, Willems SM, Wang S., Yaghootkar H., Brody JA, Dauriz M., Hivert MF, Raghavan S., Lipovich L., Hidalgo B., Fox K., Huffman JE, An P., Lu Y., Rasmussen-Torvik LJ, Grarup N., Ehm MG, Li L., Baldridge AS, et al. Nature communications, 2015/01/29, Volume 6, p.5897, (2015) Read More / View Supplemental Materials
Abstract
2014
Genome-wide association study of kidney function decline in individuals of European descent.Gorski, M., Tin A., Garnaas M., McMahon GM, Chu AY, Tayo BO, Pattaro C., Teumer A., Chasman DI, Chalmers J., Hamet P., Tremblay J., Woodward M., Aspelund T., Eiriksdottir G., Gudnason V., Harris TB, Launer LJ, Smith AV, Mitchell BD, et al. Kidney international, 2014/12/10, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.The Coffee and Caffeine Genetics, Consortium, Cornelis MC, Byrne EM, Esko T., Nalls MA, Ganna A., Paynter N., Monda KL, Amin N., Fischer K., Renstrom F., Ngwa JS, Huikari V., Cavadino A., Nolte IM, Teumer A., Yu K., Marques-Vidal P., Rawal R., Manichaikul A., et al. Molecular psychiatry, 2014/10/07, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.Swerdlow, DI, Preiss D., Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T., Sofat R., Stender S., Johnson PC, Scott RA, Leusink M., Verweij N., Sharp SJ, Guo Y., Giambartolomei C., Chung C., Peasey A., Amuzu A., Li K., Palmen J., et al. Lancet, 2014/09/24, (2014) Read More / View Supplemental Materials
Abstract
Association of exome sequences with plasma C-reactive protein levels in >9000 participants.Schick, UM, Auer PL, Bis JC, Lin H., Wei P., Pankratz N., Lange LA, Brody J., Stitziel NO, Kim DS, Carlson CS, Fornage M., Haessler J., Hsu L., Jackson RD, Kooperberg C., Leal SM, Psaty BM, Boerwinkle E., Tracy R., et al. Human molecular genetics, 2014/09/03, (2014) Read More / View Supplemental Materials
Abstract
Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation.Sinner, MF, Tucker NR, Lunetta KL, Ozaki K., Smith JG, Trompet S., Bis JC, Lin H., Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J., Gollob MH, Tsunoda T., Müller-Nurasyid M., Lichtner P., Peters A., Dolmatova E., et al. Circulation, 2014/08/14, (2014) Read More / View Supplemental Materials
Abstract
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.Perry, JR, Day F., Elks CE, Sulem P., Thompson DJ, Ferreira T., He C., Chasman DI, Esko T., Thorleifsson G., Albrecht E., Ang WQ, Corre T., Cousminer DL, Feenstra B., Franceschini N., Ganna A., Johnson AD, Kjellqvist S., Lunetta KL, et al. Nature, 2014/07/23, (2014) Read More / View Supplemental Materials
Abstract
Selectivity in Genetic Association with Sub-classified Migraine in Women.Chasman, DI, Anttila V., Buring JE, Ridker PM, Schürks M., Kurth T., and International Headache Genetics Consortium PLoS genetics, 2014/05/01, Volume 10, Issue 5, p.e1004366, (2014) Read More / View Supplemental Materials
Abstract
Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci.Tragante, V., Barnes MR, Ganesh SK, Lanktree MB, Guo W., Franceschini N., Smith EN, Johnson T., Holmes MV, Padmanabhan S., Karczewski KJ, Almoguera B., Barnard J., Baumert J., Chang YP, Elbers CC, Farrall M., Fischer ME, Gaunt TR, Gho JM, et al. American journal of human genetics, 2014/02/19, (2014) Read More / View Supplemental Materials
Abstract
2013
Common variants associated with plasma triglycerides and risk for coronary artery disease.Do, R., Willer CJ, Schmidt EM, Sengupta S., Gao C., Peloso GM, Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich ML, Mora S., Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A., Den Hertog HM, Donnelly LA, Ehret GB, Esko T., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1345-52, (2013) Read More / View Supplemental Materials
Abstract
2012
Informed conditioning on clinical covariates increases power in case-control association studies.Zaitlen, N., Lindström S., Pasaniuc B., Cornelis M., Genovese G., Pollack S., Barton A., Bickeböller H., Bowden DW, Eyre S., Freedman BI, Friedman DJ, Field JK, Groop L., Haugen A., Heinrich J., Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, et al. PLoS genetics, 2012/11/01, Volume 8, Issue 11, p.e1003032, (2012) Read More / View Supplemental Materials
Abstract
2010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.Speliotes, EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G., Jackson AU, Allen HL, Lindgren CM, Luan J., Mägi R., Randall JC, Vedantam S., Winkler TW, Qi L., Workalemahu T., Heid IM, Steinthorsdottir V., Stringham HM, Weedon MN, Wheeler E., et al. Nature genetics, 2010/11/01, Volume 42, Issue 11, p.937-48, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-24 of 24 Results