Scientific Publications

Search by Keyword(s)
Found 39 results

Filters: Author is Yang, J  [Clear All Filters]

Search Results

  • Showing 1-39 of 39 Results
2016
Genome-wide association study identifies 74 loci associated with educational attainment.Okbay, A., Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P., Chen GB, Emilsson V., Meddens SF, Oskarsson S., Pickrell JK, Thom K., Timshel P., de Vlaming R., Abdellaoui A., Ahluwalia TS, Bacelis J., Baumbach C., Bjornsdottir G., et al. Nature, 2016/05/11, Volume 533, Issue 7604, p.539-42, (2016) Read More / View Supplemental Materials
Abstract
Tumour CD274 (PD-L1) expression and T cells in colorectal cancer.Masugi, Y., Nishihara R., Yang J., Mima K., da Silva A., Shi Y., Inamura K., Cao Y., Song M., Nowak JA, Liao X., Nosho K., Chan AT, Giannakis M., Bass AJ, Hodi FS, Freeman GJ, Rodig S., Fuchs CS, Qian ZR, et al. Gut, 2016/05/05, (2016) Read More / View Supplemental Materials
Abstract
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.Okbay, A., Baselmans BM, De Neve JE, Turley P., Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J., Gratten J., Lee JJ, Liu JZ, de Vlaming R., Ahluwalia TS, Buchwald J., Cavadino A., Frazier-Wood AC, Furlotte NA, Garfield V., et al. Nature genetics, 2016/04/18, (2016) Read More / View Supplemental Materials
Abstract
Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.Yu, L., Chibnik L., Yang J., McCabe C., Xu J., Schneider JA, De Jager PL, and Bennett DA Alzheimer's & dementia : the journal of the Alzheimer's Association, 2016/03/23, (2016) Read More / View Supplemental Materials
Abstract
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts.Ma, L., Chen Z., Huang da W., Kutty G., Ishihara M., Wang H., Abouelleil A., Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., FitzGerald M., Gogineni E., Goldberg JM, Handley G., Hu X., Huber C., Jiao X., et al. Nature communications, 2016/02/22, Volume 7, p.10740, (2016) Read More / View Supplemental Materials
Abstract
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.Lu, Y., Day FR, Gustafsson S., Buchkovich ML, Na J., Bataille V., Cousminer DL, Dastani Z., Drong AW, Esko T., Evans DM, Falchi M., Feitosa MF, Ferreira T., Hedman Å. K., Haring R., Hysi PG, Iles MM, Justice AE, Kanoni S., et al. Nature communications, 2016/02/01, Volume 7, p.10495, (2016) Read More / View Supplemental Materials
Abstract
2015
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.Yang, J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen AA, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., study LifeLines Cohort, Esko T., Milani L., Mägi R., Metspalu A., Hamsten A., Magnusson PK, Pedersen NL, Ingelsson E., and Visscher PM Human molecular genetics, 2015/10/22, (2015) Read More / View Supplemental Materials
Abstract
The transcriptional landscape of age in human peripheral blood.Peters, MJ, Joehanes R., Pilling LC, Schurmann C., Conneely KN, Powell J., Reinmaa E., Sutphin GL, Zhernakova A., Schramm K., Wilson YA, Kobes S., Tukiainen T., NABEC/UKBEC Consortium, Ramos YF, Göring HH, Fornage M., Liu Y., Gharib SA, Stranger BE, et al. Nature communications, 2015/10/22, Volume 6, p.8570, (2015) Read More / View Supplemental Materials
Abstract
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.Winkler, TW, Justice AE, Graff M., Barata L., Feitosa MF, Chu S., Czajkowski J., Esko T., Fall T., Kilpeläinen TO, Lu Y., Mägi R., Mihailov E., Pers TH, Rüeger S., Teumer A., Ehret GB, Ferreira T., Heard-Costa NL, Karjalainen J., et al. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005378, (2015) Read More / View Supplemental Materials
Abstract
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.Vilhjálmsson, BJ, Yang J., Finucane HK, Gusev A., Lindström S., Ripke S., Genovese G., Loh PR, Bhatia G., Do R., Hayeck T., Won HH, and of in study Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery Biology Risk Inherited Variants Breast Cancer(DRIVE), Kathiresan S., Pato M., Pato C., Tamimi R., Stahl E., Zaitlen N., Pasaniuc B., et al. American journal of human genetics, 2015/10/01, Volume 97, Issue 4, p.576-92, (2015) Read More / View Supplemental Materials
Abstract
Population genetic differentiation of height and body mass index across Europe.Robinson, MR, Hemani G., Medina-Gomez C., Mezzavilla M., Esko T., Shakhbazov K., Powell JE, Vinkhuyzen A., Berndt SI, Gustafsson S., Justice AE, Kahali B., Locke AE, Pers TH, Vedantam S., Wood AR, van Rheenen W., Andreassen OA, Gasparini P., Metspalu A., et al. Nature genetics, 2015/09/14, (2015) Read More / View Supplemental Materials
Abstract
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.Yang, J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen AA, Lee SH, Robinson MR, Perry JR, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., study LifeLines Cohort, Esko T., Milani L., Mägi R., Metspalu A., Hamsten A., Magnusson PK, Pedersen NL, Ingelsson E., et al. Nature genetics, 2015/08/31, (2015) Read More / View Supplemental Materials
Abstract
Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis.Mima, K., Nishihara R., Qian ZR, Cao Y., Sukawa Y., Nowak JA, Yang J., Dou R., Masugi Y., Song M., Kostic AD, Giannakis M., Bullman S., Milner DA, Baba H., Giovannucci EL, Garraway LA, Freeman GJ, Dranoff G., Garrett WS, et al. Gut, 2015/08/26, (2015) Read More / View Supplemental Materials
Abstract
Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells.Sefik, E., Geva-Zatorsky N., Oh S., Konnikova L., Zemmour D., McGuire AM, Burzyn D., Ortiz-Lopez A., Lobera M., Yang J., Ghosh S., Earl A., Snapper SB, Jupp R., Kasper D., Mathis D., and Benoist C. Science (New York, N.Y.), 2015/08/13, (2015) Read More / View Supplemental Materials
Abstract
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.Yang, J., Yu L., Gaiteri C., Srivastava GP, Chibnik LB, Leurgans SE, Schneider JA, Meissner A., De Jager PL, and Bennett DA The international journal of biochemistry & cell biology, 2015/05/21, (2015) Read More / View Supplemental Materials
Abstract
Mendelian randomization study of height and risk of colorectal cancer.Thrift, AP, Gong J., Peters U., Chang-Claude J., Rudolph A., Slattery ML, Chan AT, Esko T., Wood AR, Yang J., Vedantam S., Gustafsson S., Pers TH, GIANT Consortium, Baron JA, Bezieau S., Küry S., Ogino S., Berndt SI, Casey G., et al. International journal of epidemiology, 2015/05/20, (2015) Read More / View Supplemental Materials
Abstract
Mixed Model with Correction for Case-Control Ascertainment Increases Association Power.Hayeck, TJ, Zaitlen NA, Loh PR, Vilhjalmsson B., Pollack S., Gusev A., Yang J., Chen GB, Goddard ME, Visscher PM, Patterson N., and Price AL American journal of human genetics, 2015/04/14, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits.Zhu, Z., Bakshi A., Vinkhuyzen AA, Hemani G., Lee SH, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., The LifeLines Cohort Study, Esko T., Milani L., Mägi R., Metspalu A., Hill WG, Weir BS, Goddard ME, Visscher PM, and Yang J. American journal of human genetics, 2015/02/11, (2015) Read More / View Supplemental Materials
Abstract
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.Yu, L., De Jager PL, Yang J., Trojanowski JQ, Bennett DA, and Schneider JA Neurology, 2015/02/04, (2015) Read More / View Supplemental Materials
Abstract
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.Bulik-Sullivan, BK, Loh PR, Finucane HK, Ripke S., Yang J., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson N., Daly M. J., Price AL, and Neale BM Nature genetics, 2015/02/02, (2015) Read More / View Supplemental Materials
Abstract
Biological interpretation of genome-wide association studies using predicted gene functions.Pers, TH, Karjalainen JM, Chan Y., Westra HJ, Wood AR, Yang J., Lui JC, Vedantam S., Gustafsson S., Esko T., Frayling T., Speliotes EK, Genetic Investigation of ANthropometric Traits(GIANT) Consortium, Boehnke M., Raychaudhuri S., Fehrmann RS, Hirschhorn JN, and Franke L. Nature communications, 2015/01/19, Volume 6, p.5890, (2015) Read More / View Supplemental Materials
Abstract
2014
Association of Brain DNA Methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 With Pathological Diagnosis of Alzheimer Disease.Yu, L., Chibnik LB, Srivastava GP, Pochet N., Yang J., Xu J., Kozubek J., Obholzer N., Leurgans SE, Schneider JA, Meissner A., De Jager PL, and Bennett DA JAMA neurology, 2014/11/03, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
Hemani et al. reply.Hemani, G., Shakhbazov K., Westra HJ, Esko T., Henders AK, McRae AF, Yang J., Gibson G., Martin NG, Metspalu A., Franke L., Montgomery GW, Visscher PM, and Powell JE Nature, 2014/10/02, Volume 514, Issue 7520, p.E5-6, (2014) Read More / View Supplemental Materials
Multiple Associated Variants Increase the Heritability Explained for Plasma Lipids and Coronary Artery Disease.Tada, H., Won HH, Melander O., Yang J., Peloso GM, and Kathiresan S. Circulation. Cardiovascular genetics, 2014/08/28, (2014) Read More / View Supplemental Materials
Abstract
The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort.Robinson, EB, Kirby A., Ruparel K., Yang J., McGrath L., Anttila V., Neale BM, Merikangas K., Lehner T., Sleiman PM, Daly M. J., Gur R., Gur R., and Hakonarson H. Molecular psychiatry, 2014/07/15, (2014) Read More / View Supplemental Materials
Abstract
Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.Pugh, TJ, Yu W., Yang J., Field AL, Ambrogio L., Carter SL, Cibulskis K., Giannikopoulos P., Kiezun A., Kim J., McKenna A., Nickerson E., Getz G., Hoffher S., Messinger YH, Dehner LP, Roberts CW, Rodriguez-Galindo C., Williams GM, Rossi CT, et al. Oncogene, 2014/06/09, (2014) Read More / View Supplemental Materials
Abstract
Epigenomics of Alzheimer's disease.Bennett, DA, Yu L., Yang J., Srivastava GP, Aubin C., and De Jager PL Translational research : the journal of laboratory and clinical medicine, 2014/05/16, (2014) Read More / View Supplemental Materials
Abstract
Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.Xiao, S., Yosef N., Yang J., Wang Y., Zhou L., Zhu C., Wu C., Baloglu E., Schmidt D., Ramesh R., Lobera M., Sundrud MS, Tsai PY, Xiang Z., Wang J., Xu Y., Lin X., Kretschmer K., Rahl PB, Young RA, et al. Immunity, 2014/04/17, Volume 40, Issue 4, p.477-89, (2014) Read More / View Supplemental Materials
Abstract
Detection and replication of epistasis influencing transcription in humans.Hemani, G., Shakhbazov K., Westra HJ, Esko T., Henders AK, McRae AF, Yang J., Gibson G., Martin NG, Metspalu A., Franke L., Montgomery GW, Visscher PM, and Powell JE Nature, 2014/02/26, (2014) Read More / View Supplemental Materials
Abstract
Advantages and pitfalls in the application of mixed-model association methods.Yang, J., Zaitlen NA, Goddard ME, Visscher PM, and Price AL Nature genetics, 2014/02/01, Volume 46, Issue 2, p.100-6, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Response to 'Predicting the diagnosis of autism spectrum disorder using gene pathway analysis'Robinson, EB, Howrigan D., Yang J., Ripke S., Anttila V., Duncan LE, Jostins L., Barrett JC, Medland SE, Macarthur DG, Breen G., O'Donovan MC, Wray NR, Devlin B., Daly M. J., Visscher PM, Sullivan PF, and Neale BM Molecular psychiatry, 2013/10/22, (2013) Read More / View Supplemental Materials
2010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.Speliotes, EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G., Jackson AU, Allen HL, Lindgren CM, Luan J., Mägi R., Randall JC, Vedantam S., Winkler TW, Qi L., Workalemahu T., Heid IM, Steinthorsdottir V., Stringham HM, Weedon MN, Wheeler E., et al. Nature genetics, 2010/11/01, Volume 42, Issue 11, p.937-48, (2010) Read More / View Supplemental Materials
Abstract
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes.Taube, JH, Herschkowitz JI, Komurov K., Zhou AY, Gupta S., Yang J., Hartwell K., Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander E. S., Rosen JM, Weinberg R. A., and Mani SA Proceedings of the National Academy of Sciences of the United States of America, 2010/08/31, Volume 107, Issue 35, p.15449-54, (2010) Read More / View Supplemental Materials
Abstract
2008
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.Onder, TT, Gupta PB, Mani SA, Yang J., Lander E. S., and Weinberg R. A. Cancer research, 2008/05/15, Volume 68, Issue 10, p.3645-54, (2008) Read More / View Supplemental Materials
Abstract
2007
Identification of a small-molecule inhibitor of class Ia PI3Ks with cell-based screening.Yang, J., Shamji A., Matchacheep S., and Schreiber SL Chemistry & biology, 2007/04/01, Volume 14, Issue 4, p.371-7, (2007) Read More / View Supplemental Materials
Abstract
  • Showing 1-39 of 39 Results