Recent Broad Publications

Hopping between Differentiation States in Lung Adenocarcinoma.
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Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
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The Genome of Anopheles darlingi, the main neotropical malaria vector.
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ATHLATES: accurate typing of human leukocyte antigen through exome sequencing.
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Integrated proteomic analysis of post-translational modifications by serial enrichment.
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Scientific Publications

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Filters: Author is Kesavan, S [Clear All Filters]

2013

Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.Gerard, B., Lee MD 4th, Dandapani S., Duvall JR, Fitzgerald ME, Kesavan S., Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M., Hamann D., Lemercier B., Murillo T., Akella LB, Foley MA, and Marcaurelle LA The Journal of organic chemistry, 2013/06/07, Volume 78, Issue 11, p.5160-71, (2013) Read More / View Supplemental Materials

2012

Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahydroquinoline Library.Gerard, B., O'Shea MW, Donckele E., Kesavan S., Akella LB, Xu H., Jacobsen EN, and Marcaurelle LA ACS combinatorial science, 2012/10/22, (2012) Read More / View Supplemental Materials

Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries.Lowe, JT, Lee MD 4th, Akella LB, Davoine E., Donckele EJ, Durak L., Duvall JR, Gerard B., Holson EB, Joliton A., Kesavan S., Lemercier BC, Liu H., Marié JC, Mulrooney CA, Muncipinto G., Welzel-O'Shea M., Panko LM, Rowley A., Suh BC, et al. The Journal of organic chemistry, 2012/08/10, (2012) Read More / View Supplemental Materials

2010

An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Marcaurelle, LA, Comer E., Dandapani S., Duvall JR, Gerard B., Kesavan S., Lee MD 4th, Liu H., Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A., Ryba TD, Suh BC, Wei J., Young DW, Akella LB, Ross NT, Zhang YL, et al. Journal of the American Chemical Society, 2010/12/01, Volume 132, Issue 47, p.16962-76, (2010) Read More / View Supplemental Materials

2009

Accessing skeletal diversity using catalyst control: formation of n and n + 1 macrocyclic triazole rings.Kelly, AR, Wei J., Kesavan S., Marié JC, Windmon N., Young DW, and Marcaurelle LA Organic letters, 2009/06/04, Volume 11, Issue 11, p.2257-60, (2009) Read More / View Supplemental Materials