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2014
Systematic identification of signaling pathways with potential to confer anticancer drug resistance.Martz, CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A., Anderson GR, Winter PS, Wang T., Alley HM, Kwong LN, Cooper ZA, Tetzlaff M., Chen PL, Rathmell JC, Flaherty KT, Wargo JA, McDonnell DP, Sabatini DM, and Wood KC Science signaling, 2014/12/23, Volume 7, Issue 357, p.ra121, (2014) Read More / View Supplemental Materials
Abstract
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.Konieczkowski, DJ, Johannessen CM, Abudayyeh O., Kim JW, Cooper ZA, Piris A., Frederick DT, Barzily-Rokni M., Straussman R., Haq R., Fisher DE, Mesirov J. P., Hahn WC, Flaherty KT, Wargo JA, Tamayo P., and Garraway LA Cancer discovery, 2014/04/25, (2014) Read More / View Supplemental Materials
Abstract
2013
A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.Johannessen, CM, Johnson LA, Piccioni F., Townes A., Frederick DT, Donahue MK, Narayan R., Flaherty KT, Wargo JA, Root DE, and Garraway LA Nature, 2013/11/03, (2013) Read More / View Supplemental Materials
Abstract
2012
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.Straussman, R., Morikawa T., Shee K., Barzily-Rokni M., Qian ZR, Du J., Davis A., Mongare MM, Gould J., Frederick DT, Cooper ZA, Chapman PB, Solit DB, Ribas A., Lo RS, Flaherty KT, Ogino S., Wargo JA, and Golub T. R. Nature, 2012/07/04, (2012) Read More / View Supplemental Materials
Abstract
2010
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.Johannessen, CM, Boehm JS, Kim SY, Thomas SR, Wardwell L., Johnson LA, Emery CM, Stransky N., Cogdill AP, Barretina J., Caponigro G., Hieronymus H., Murray RR, Salehi-Ashtiani K., Hill DE, Vidal M., Zhao JJ, Yang X., Alkan O., Kim S., et al. Nature, 2010/12/16, Volume 468, Issue 7326, p.968-72, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-5 of 5 Results