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2016
Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.Zhang, X., Chen MH, Wu X., Kodani A., Fan J., Doan R., Ozawa M., Ma J., Yoshida N., Reiter JF, Black DL, Kharchenko PV, Sharp PA, and Walsh CA Cell, 2016/08/25, Volume 166, Issue 5, p.1147-1162.e15, (2016) Read More / View Supplemental Materials
Abstract
High-throughput Phenotyping of Lung Cancer Somatic Mutations.Berger, AH, Brooks AN, Wu X., Shrestha Y., Chouinard C., Piccioni F., Bagul M., Kamburov A., Imielinski M., Hogstrom L., Zhu C., Yang X., Pantel S., Sakai R., Watson J., Kaplan N., Campbell JD, Singh S., Root DE, Narayan R., et al. Cancer cell, 2016/07/28, (2016) Read More / View Supplemental Materials
Abstract
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.Machiela, MJ, Zhou W., Karlins E., Sampson JN, Freedman ND, Yang Q., Hicks B., Dagnall C., Hautman C., Jacobs KB, Abnet CC, Aldrich MC, Amos C., Amundadottir LT, Arslan AA, Beane-Freeman LE, Berndt SI, Black A., Blot WJ, Bock CH, et al. Nature communications, 2016/06/13, Volume 7, p.11843, (2016) Read More / View Supplemental Materials
Abstract
Systematic functional interrogation of rare cancer variants identifies oncogenic alleles.Kim, E., Ilic N., Shrestha Y., Zou L., Kamburov A., Zhu C., Yang X., Lubonja R., Tran N., Nguyen C., Lawrence MS, Piccioni F., Bagul M., Doench JG, Chouinard CR, Wu X., Hogstrom L., Natoli T., Tamayo P., Horn H., et al. Cancer discovery, 2016/05/04, (2016) Read More / View Supplemental Materials
Abstract
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.de Waal, L., Lewis TA, Rees MG, Tsherniak A., Wu X., Choi PS, Hartigan C., Faloon PW, Hickey MJ, Tolliday N., Carr SA, Clemons PA, Munoz B., Wagner BK, Shamji AF, Koehler AN, Schenone M., Burgin AB, Schreiber SL, Greulich H., et al. Nature chemical biology, 2016/02/01, Volume 12, Issue 2, p.102-8, (2016) Read More / View Supplemental Materials
Abstract
Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.Figueroa, JD, Middlebrooks CD, Banday AR, Ye Y., Garcia-Closas M., Chatterjee N., Koutros S., Kiemeney LA, Rafnar T., Bishop T., Barnes HF, Matullo G., Golka K., Gago-Dominguez M., Taylor J., Fletcher T., Siddiq A., Cortessis VK, Kooperberg C., Cussenot O., et al. Human molecular genetics, 2016/01/04, (2016) Read More / View Supplemental Materials
Abstract
2015
Association studies of genomic variants with treatment response to risperidone, clozapine, quetiapine and chlorpromazine in the Chinese Han population.Xu, Q., Wu X., Li M., Huang H., Minica C., Yi Z., Wang G., Shen L., Xing Q., Shi Y., He L., and Qin S. The pharmacogenomics journal, 2015/08/18, (2015) Read More / View Supplemental Materials
Abstract
Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects.Singh, S., Wu X., Ljosa V., Bray MA, Piccioni F., Root DE, Doench JG, Boehm JS, and Carpenter AE PloS one, 2015/07/21, Volume 10, Issue 7, p.e0131370, (2015) Read More / View Supplemental Materials
Abstract
In vivo genome editing using Staphylococcus aureus Cas9.Ran, FA, Cong L., Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B., Shalem O., Wu X., Makarova KS, Koonin EV, Sharp PA, and Zhang F. Nature, 2015/04/09, Volume 520, Issue 7546, p.186-91, (2015) Read More / View Supplemental Materials
Abstract
Characterization of large structural genetic mosaicism in human autosomes.Machiela, MJ, Zhou W., Sampson JN, Dean MC, Jacobs KB, Black A., Brinton LA, Chang IS, Chen C., Chen C., Chen K., Cook LS, Crous Bou M., De Vivo I., Doherty J., Friedenreich CM, Gaudet MM, Haiman CA, Hankinson SE, Hartge P., et al. American journal of human genetics, 2015/03/05, Volume 96, Issue 3, p.487-97, (2015) Read More / View Supplemental Materials
Abstract
Building the Connectivity Map of epigenetics: chromatin profiling by quantitative targeted mass spectrometry.Creech, AL, Taylor JE, Maier VK, Wu X., Feeney CM, Udeshi ND, Peach SE, Boehm JS, Lee JT, Carr SA, and Jaffe JD Methods (San Diego, Calif.), 2015/01/15, Volume 72, p.57-64, (2015) Read More / View Supplemental Materials
Abstract
2014
Genome-wide Scan of 29,141 African Americans Finds No Evidence of Directional Selection since Admixture.Bhatia, G., Tandon A., Patterson N., Aldrich MC, Ambrosone CB, Amos C., Bandera EV, Berndt SI, Bernstein L., Blot WJ, Bock CH, Caporaso N., Casey G., Deming SL, Diver WR, Gapstur SM, Gillanders EM, Harris CC, Henderson BE, Ingles SA, et al. American journal of human genetics, 2014/09/17, (2014) Read More / View Supplemental Materials
Abstract
Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.Wang, Z., Zhu B., Zhang M., Parikh H., Jia J., Chung CC, Sampson JN, Hoskins JW, Hutchinson A., Burdette L., Ibrahim A., Hautman C., Raj PS, Abnet CC, Adjei AA, Ahlbom A., Albanes D., Allen NE, Ambrosone CB, Aldrich M., et al. Human molecular genetics, 2014/07/15, (2014) Read More / View Supplemental Materials
Abstract
Global microRNA depletion suppresses tumor angiogenesis.Chen, S., Xue Y., Wu X., Le C., Bhutkar A., Bell EL, Zhang F., Langer R., and Sharp PA Genes & development, 2014/05/15, Volume 28, Issue 10, p.1054-67, (2014) Read More / View Supplemental Materials
Abstract
A Genome-Wide Association Study Identifies Variants in Casein Kinase II (CSNK2A2) to be Associated with Leukocyte Telomere Length in a Punjabi Sikh Diabetic Cohort.Saxena, R., Bjonnes A., Prescott J., Dib P., Natt P., Lane J., Lerner M., Cooper JA, Ye Y., Li KW, Maubaret CG, Codd V., Brackett D., Mirabello L., Kraft P., Dinney CP, Stowell D., Peyton M., Ralhan S., Wander GS, et al. Circulation. Cardiovascular genetics, 2014/05/03, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.Wu, X., Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S., Chen S., Jaenisch R., Zhang F., and Sharp PA Nature biotechnology, 2014/04/20, (2014) Read More / View Supplemental Materials
Abstract
2013
DNA targeting specificity of RNA-guided Cas9 nucleases.Hsu, PD, Scott DA, Weinstein JA, Ran FA, Konermann S., Agarwala V., Li Y., Fine EJ, Wu X., Shalem O., Cradick TJ, Marraffini LA, Bao G., and Zhang F. Nature biotechnology, 2013/07/21, (2013) Read More / View Supplemental Materials
Abstract
Multiplex Genome Engineering Using CRISPR/Cas Systems.Cong, L., Ran FA, Cox D., Lin S., Barretto R., Habib N., Hsu PD, Wu X., Jiang W., Marraffini LA, and Zhang F. Science (New York, N.Y.), 2013/01/03, (2013) Read More / View Supplemental Materials
Abstract
2011
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.Ding, Z., Wu CJ, Chu GC, Xiao Y., Ho D., Zhang J., Perry SR, Labrot ES, Wu X., Lis R., Hoshida Y., Hiller D., Hu B., Jiang S., Zheng H., Stegh AH, Scott KL, Signoretti S., Bardeesy N., Wang YA, et al. Nature, 2011/02/10, Volume 470, Issue 7333, p.269-73, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-19 of 19 Results