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2005
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.Garraway, LA, Widlund HR, Rubin MA, Getz G., Berger AJ, Ramaswamy S., Beroukhim R., Milner DA, Granter SR, Du J., Lee C., Wagner SN, Li C., Golub T. R., Rimm DL, Meyerson ML, Fisher DE, and Sellers WR Nature, 2005/07/07, Volume 436, Issue 7047, p.117-22, (2005) Read More / View Supplemental Materials
Abstract
An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray.Ebert, BL, Lee MM, Pretz JL, Subramanian A., Mak R., Golub T. R., and Sieff CA Blood, 2005/06/15, Volume 105, Issue 12, p.4620-6, (2005) Read More / View Supplemental Materials
Abstract
MicroRNA expression profiles classify human cancers.Lu, J., Getz G., Miska EA, Alvarez-Saavedra E., Lamb J., Peck D., Sweet-Cordero A., Ebert BL, Mak RH, Ferrando AA, Downing J. R., Jacks T., Horvitz HR, and Golub T. R. Nature, 2005/06/09, Volume 435, Issue 7043, p.834-8, (2005) Read More / View Supplemental Materials
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Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer.Febbo, PG, Lowenberg M., Thorner AR, Brown M., Loda M., and Golub T. R. The Journal of urology, 2005/05/01, Volume 173, Issue 5, p.1772-7, (2005) Read More / View Supplemental Materials
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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.Levine, RL, Wadleigh M., Cools J., Ebert BL, Wernig G., Huntly BJ, Boggon TJ, Wlodarska I., Clark JJ, Moore S., Adelsperger J., Koo S., Lee JC, Gabriel S., Mercher T., D'Andrea A., Fröhling S., Döhner K., Marynen P., Vandenberghe P., et al. Cancer cell, 2005/04/01, Volume 7, Issue 4, p.387-97, (2005) Read More / View Supplemental Materials
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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals.Xie, X., Lu J., Kulbokas E. J., Golub T. R., Mootha V., Lindblad-Toh K., Lander E. S., and Kellis M. Nature, 2005/03/17, Volume 434, Issue 7031, p.338-45, (2005) Read More / View Supplemental Materials
Abstract
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response.Monti, S., Savage KJ, Kutok JL, Feuerhake F., Kurtin P., Mihm M., Wu B., Pasqualucci L., Neuberg D., Aguiar RC, Dal Cin P., Ladd C., Pinkus GS, Salles G., Harris NL, Dalla-Favera R., Habermann TM, Aster J. C., Golub T. R., and Shipp M. A. Blood, 2005/03/01, Volume 105, Issue 5, p.1851-61, (2005) Read More / View Supplemental Materials
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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.Wang, J., Iwasaki H., Krivtsov A., Febbo PG, Thorner AR, Ernst P., Anastasiadou E., Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub T. R., Armstrong SA, Akashi K., and Korsmeyer SJ The EMBO journal, 2005/01/26, Volume 24, Issue 2, p.368-81, (2005) Read More / View Supplemental Materials
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An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.Sweet-Cordero, A., Mukherjee S., Subramanian A., You H., Roix JJ, Ladd-Acosta C., Mesirov J., Golub T. R., and Jacks T. Nature genetics, 2005/01/01, Volume 37, Issue 1, p.48-55, (2005) Read More / View Supplemental Materials
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2004
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells.Berger, R., Febbo PG, Majumder PK, Zhao JJ, Mukherjee S., Signoretti S., Campbell KT, Sellers WR, Roberts TM, Loda M., Golub T. R., and Hahn WC Cancer research, 2004/12/15, Volume 64, Issue 24, p.8867-75, (2004) Read More / View Supplemental Materials
Abstract
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.Du, J., Widlund HR, Horstmann MA, Ramaswamy S., Ross K., Huber WE, Nishimura EK, Golub T. R., and Fisher DE Cancer cell, 2004/12/01, Volume 6, Issue 6, p.565-76, (2004) Read More / View Supplemental Materials
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Genomic approaches to hematologic malignancies.Ebert, BL, and Golub T. R. Blood, 2004/08/15, Volume 104, Issue 4, p.923-32, (2004) Read More / View Supplemental Materials
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Toward a functional taxonomy of cancer.Golub, T. R. Cancer cell, 2004/08/01, Volume 6, Issue 2, p.107-8, (2004) Read More / View Supplemental Materials
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A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer.Halmos, B., Bassères DS, Monti S., D'Aló F., Dayaram T., Ferenczi K., Wouters BJ, Huettner CS, Golub T. R., and Tenen D. G. Cancer research, 2004/06/15, Volume 64, Issue 12, p.4137-47, (2004) Read More / View Supplemental Materials
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mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.Majumder, PK, Febbo PG, Bikoff R., Berger R., Xue Q., McMahon LM, Manola J., Brugarolas J., McDonnell TJ, Golub T. R., Loda M., Lane HA, and Sellers WR Nature medicine, 2004/06/01, Volume 10, Issue 6, p.594-601, (2004) Read More / View Supplemental Materials
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The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1.Coletta, RD, Christensen K., Reichenberger KJ, Lamb J., Micomonaco D., Huang L., Wolf DM, Müller-Tidow C., Golub T. R., Kawakami K., and Ford HL Proceedings of the National Academy of Sciences of the United States of America, 2004/04/27, Volume 101, Issue 17, p.6478-83, (2004) Read More / View Supplemental Materials
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Metagenes and molecular pattern discovery using matrix factorization.Brunet, JP, Tamayo P., Golub T. R., and Mesirov J. P. Proceedings of the National Academy of Sciences of the United States of America, 2004/03/23, Volume 101, Issue 12, p.4164-9, (2004) Read More / View Supplemental Materials
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Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.Stegmaier, K., Ross KN, Colavito SA, O'Malley S., Stockwell BR, and Golub T. R. Nature genetics, 2004/03/01, Volume 36, Issue 3, p.257-63, (2004) Read More / View Supplemental Materials
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2001
Multiclass cancer diagnosis using tumor gene expression signaturesRamaswamy, S., Tamayo P., Rifkin R., Mukherjee S., Yeang C. H., Angelo M., Ladd C., Reich M., Latulippe E., Mesirov J. P., Poggio T., Gerald W., Loda M., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2001/12/18/, Volume 98, Issue 26, p.15149 - 54, (2001) Read More / View Supplemental Materials
Abstract
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclassesBhattacharjee, A., Richards W. G., Staunton J., Li C., Monti S., Vasa P., Ladd C., Beheshti J., Bueno R., Gillette M., Loda M., Weber G., Mark E. J., Lander E. S., Wong W., Johnson B. E., Golub T. R., Sugarbaker D. J., and Meyerson M. Proceedings of the National Academy of Sciences of the United States of America, 2001/11/20/, Volume 98, Issue 24, p.13790 - 5, (2001) Read More / View Supplemental Materials
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Chemosensitivity prediction by transcriptional profilingStaunton, J. E., Slonim D. K., Coller H. A., Tamayo P., Angelo M. J., Park J., Scherf U., Lee J. K., Reinhold W. O., Weinstein J. N., Mesirov J. P., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2001/09/11/, Volume 98, Issue 19, p.10787 - 92, (2001) Read More / View Supplemental Materials
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c-Myc is a critical target for c/EBPalpha in granulopoiesisJohansen, L. M., Iwama A., Lodie T. A., Sasaki K., Felsher D. W., Golub T. R., and Tenen D. G. Molecular and Cellular Biology, 2001/06//, Volume 21, Issue 11, p.3789 - 806, (2001) Read More / View Supplemental Materials
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Genome-wide views of cancerGolub, T. R. The New England Journal of Medicine, 2001/02/22/, Volume 344, Issue 8, p.601 - 2, (2001) Read More / View Supplemental Materials
Genome-wide views of cancerGolub, T. R. The New England Journal of Medicine, 2001/02/22/, Volume 344, Issue 8, p.601 - 2, (2001) Read More / View Supplemental Materials
2000
Genomic analysis of metastasis reveals an essential role for RhoCClark, E. A., Golub T. R., Lander E. S., and Hynes R. O. Nature, 2000/08/03/, Volume 406, Issue 6795, p.532 - 5, (2000) Read More / View Supplemental Materials
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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesionColler, H. A., Grandori C., Tamayo P., Colbert T., Lander E. S., Eisenman R. N., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2000/03/28/, Volume 97, Issue 7, p.3260 - 5, (2000) Read More / View Supplemental Materials
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1999
Molecular classification of cancer: class discovery and class prediction by gene expression monitoringGolub, T. R., Slonim D. K., Tamayo P., Huard C., Gaasenbeek M., Mesirov J. P., Coller H., Loh M. L., Downing J. R., Caligiuri M. A., Bloomfield C. D., and Lander E. S. Science (New York, N.Y.), 1999/10/15/, Volume 286, Issue 5439, p.531 - 7, (1999) Read More / View Supplemental Materials
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Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiationTamayo, P., Slonim D., Mesirov J., Zhu Q., Kitareewan S., Dmitrovsky E., Lander E. S., and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 1999/03/16/, Volume 96, Issue 6, p.2907 - 12, (1999) Read More / View Supplemental Materials
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