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2016
Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation.Obeng, EA, Chappell RJ, Seiler M., Chen MC, Campagna DR, Schmidt PJ, Schneider RK, Lord AM, Wang L., Gambe RG, McConkey ME, Ali AM, Raza A., Yu L., Buonamici S., Smith PG, Mullally A., Wu CJ, Fleming MD, and Ebert BL Cancer cell, 2016/09/12, Volume 30, Issue 3, p.404-17, (2016) Read More / View Supplemental Materials
Abstract
Ipilimumab for Patients with Relapse after Allogeneic Transplantation.Davids, MS, Kim HT, Bachireddy P., Costello C., Liguori R., Savell A., Lukez AP, Avigan D., Chen YB, McSweeney P., LeBoeuf NR, Rooney MS, Bowden M., Zhou CW, Granter SR, Hornick JL, Rodig SJ, Hirakawa M., Severgnini M., Hodi FS, et al. The New England journal of medicine, 2016/07/14, Volume 375, Issue 2, p.143-53, (2016) Read More / View Supplemental Materials
Abstract
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition.Burger, JA, Landau DA, Taylor-Weiner A., Bozic I., Zhang H., Sarosiek K., Wang L., Stewart C., Fan J., Hoellenriegel J., Sivina M., Dubuc AM, Fraser C., Han Y., Li S., Livak KJ, Zou L., Wan Y., Konoplev S., Sougnez C., et al. Nature communications, 2016/05/20, Volume 7, p.11589, (2016) Read More / View Supplemental Materials
Abstract
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.Campbell, JD, Alexandrov A., Kim J., Wala J., Berger AH, Pedamallu CS, Shukla SA, Guo G., Brooks AN, Murray BA, Imielinski M., Hu X., Ling S., Akbani R., Rosenberg M., Cibulskis C., Ramachandran A., Collisson EA, Kwiatkowski DJ, Lawrence MS, et al. Nature genetics, 2016/05/09, (2016) Read More / View Supplemental Materials
Abstract
Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.Giannakis, M., Mu XJ, Shukla SA, Qian ZR, Cohen O., Nishihara R., Bahl S., Cao Y., Amin-Mansour A., Yamauchi M., Sukawa Y., Stewart C., Rosenberg M., Mima K., Inamura K., Nosho K., Nowak JA, Lawrence MS, Giovannucci EL, Chan AT, et al. Cell reports, 2016/04/14, (2016) Read More / View Supplemental Materials
Abstract
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.McGranahan, N., Furness AJ, Rosenthal R., Ramskov S., Lyngaa R., Saini SK, Jamal-Hanjani M., Wilson GA, Birkbak NJ, Hiley CT, Watkins TB, Shafi S., Murugaesu N., Mitter R., Akarca AU, Linares J., Marafioti T., Henry JY, Van Allen EM, Miao D., et al. Science (New York, N.Y.), 2016/03/03, (2016) Read More / View Supplemental Materials
Abstract
Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer.Strickland, KC, Howitt BE, Shukla SA, Rodig S., Ritterhouse LL, Liu JF, Garber JE, Chowdhury D., Wu CJ, D'Andrea AD, Matulonis UA, and Konstantinopoulos PA Oncotarget, 2016/02/09, (2016) Read More / View Supplemental Materials
Abstract
2015
Mutations driving CLL and their evolution in progression and relapse.Landau, DA, Tausch E., Taylor-Weiner AN, Stewart C., Reiter JG, Bahlo J., Kluth S., Bozic I., Lawrence M., Böttcher S., Carter SL, Cibulskis K., Mertens D., Sougnez CL, Rosenberg M., Hess JM, Edelmann J., Kless S., Kneba M., Ritgen M., et al. Nature, 2015/10/22, Volume 526, Issue 7574, p.525-30, (2015) Read More / View Supplemental Materials
Abstract
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.Van Allen, EM, Miao D., Schilling B., Shukla SA, Blank C., Zimmer L., Sucker A., Hillen U., Foppen MH, Goldinger SM, Utikal J., Hassel JC, Weide B., Kaehler KC, Loquai C., Mohr P., Gutzmer R., Dummer R., Gabriel S., Wu CJ, et al. Science (New York, N.Y.), 2015/10/09, Volume 350, Issue 6257, p.207-11, (2015) Read More / View Supplemental Materials
Abstract
Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes.Shukla, SA, Rooney MS, Rajasagi M., Tiao G., Dixon PM, Lawrence MS, Lane WJ, Steelman S., Sougnez C., Cibulskis K., Kiezun A., Hacohen N., Brusic V., Wu CJ, and Getz G. Nature biotechnology, 2015/09/15, (2015) Read More / View Supplemental Materials
Abstract
Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1.Howitt, BE, Shukla SA, Sholl LM, Ritterhouse LL, Watkins JC, Rodig S., Stover E., Strickland KC, D'Andrea AD, Wu CJ, Matulonis UA, and Konstantinopoulos PA JAMA oncology, 2015/07/09, (2015) Read More / View Supplemental Materials
Abstract
Haematological malignancies: at the forefront of immunotherapeutic innovation.Bachireddy, P., Burkhardt UE, Rajasagi M., and Wu CJ Nature reviews. Cancer, 2015/04/01, Volume 15, Issue 4, p.201-15, (2015) Read More / View Supplemental Materials
Abstract
Molecular and genetic properties of tumors associated with local immune cytolytic activity.Rooney, MS, Shukla SA, Wu CJ, Getz G., and Hacohen N. Cell, 2015/01/15, Volume 160, Issue 1-2, p.48-61, (2015) Read More / View Supplemental Materials
Abstract
2014
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.Landau, DA, Clement K., Ziller MJ, Boyle P., Fan J., Gu H., Stevenson K., Sougnez C., Wang L., Li S., Kotliar D., Zhang W., Ghandi M., Garraway L., Fernandes SM, Livak KJ, Gabriel S., Gnirke A., Lander E. S., Brown JR, et al. Cancer cell, 2014/12/08, Volume 26, Issue 6, p.813-25, (2014) Read More / View Supplemental Materials
Abstract
Evolving Understanding of the CLL Genome.Gruber, M., and Wu CJ Seminars in hematology, 2014/07/01, Volume 51, Issue 3, p.177-87, (2014) Read More / View Supplemental Materials
Abstract
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia.Rajasagi, M., Shukla SA, Fritsch EF, Keskin DB, Deluca D., Carmona E., Zhang W., Sougnez C., Cibulskis K., Sidney J., Stevenson K., Ritz J., Neuberg D., Brusic V., Gabriel S., Lander E. S., Getz G., Hacohen N., and Wu CJ Blood, 2014/06/02, (2014) Read More / View Supplemental Materials
Abstract
HLA-Binding Properties of Tumor Neoepitopes in Humans.Fritsch, EF, Rajasagi M., Ott PA, Brusic V., Hacohen N., and Wu CJ Cancer immunology research, 2014/06/01, Volume 2, Issue 6, p.522-9, (2014) Read More / View Supplemental Materials
Abstract
Vaccines and Melanoma.Ott, PA, Fritsch EF, Wu CJ, and Dranoff G. Hematology/oncology clinics of North America, 2014/06/01, Volume 28, Issue 3, p.559-569, (2014) Read More / View Supplemental Materials
Abstract
Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.Wang, L., Shalek AK, Lawrence M., Ding R., Gaublomme JT, Pochet N., Stojanov P., Sougnez C., Shukla SA, Stevenson KE, Zhang W., Wong J., Sievers QL, Macdonald BT, Vartanov AR, Goldstein NR, Neuberg D., He X., Lander E., Hacohen N., et al. Blood, 2014/04/28, (2014) Read More / View Supplemental Materials
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Personal neoantigen cancer vaccines: The momentum builds.Fritsch, EF, Hacohen N., and Wu CJ Oncoimmunology, 2014/01/01, Volume 3, p.e29311, (2014) Read More / View Supplemental Materials
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2013
The somatic genomic landscape of glioblastoma.Brennan, CW, Verhaak RG, McKenna A., Campos B., Noushmehr H., Salama SR, Zheng S., Chakravarty D., Sanborn JZ, Berman SH, Beroukhim R., Bernard B., Wu CJ, Genovese G., Shmulevich I., Barnholtz-Sloan J., Zou L., Vegesna R., Shukla SA, Ciriello G., et al. Cell, 2013/10/10, Volume 155, Issue 2, p.462-77, (2013) Read More / View Supplemental Materials
Abstract
The Cancer Genome Atlas Pan-Cancer analysis project.Cancer Genome Atlas Research, Network, Genome Characterization Center, Chang K., Creighton CJ, Davis C., Donehower L., Drummond J., Wheeler D., Ally A., Balasundaram M., Birol I., Butterfield YS, Chu A., Chuah E., Chun HJ, Dhalla N., Guin R., Hirst M., Hirst C., Holt RA, et al. Nature genetics, 2013/09/26, Volume 45, Issue 10, p.1113-20, (2013) Read More / View Supplemental Materials
Clonal evolution in hematological malignancies and therapeutic implications.Landau, DA, Carter SL, Getz G., and Wu CJ Leukemia, 2013/08/27, (2013) Read More / View Supplemental Materials
Abstract
Mutational heterogeneity in cancer and the search for new cancer-associated genes.Lawrence, MS, Stojanov P., Polak P., Kryukov GV, Cibulskis K., Sivachenko A., Carter SL, Stewart C., Mermel CH, Roberts SA, Kiezun A., Hammerman PS, McKenna A., Drier Y., Zou L., Ramos AH, Pugh TJ, Stransky N., Helman E., Kim J., et al. Nature, 2013/07/11, Volume 499, Issue 7457, p.214-8, (2013) Read More / View Supplemental Materials
Abstract
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.Landau, DA, Carter SL, Stojanov P., McKenna A., Stevenson K., Lawrence MS, Sougnez C., Stewart C., Sivachenko A., Wang L., Wan Y., Zhang W., Shukla SA, Vartanov A., Fernandes SM, Saksena G., Cibulskis K., Tesar B., Gabriel S., Hacohen N., et al. Cell, 2013/02/14, Volume 152, Issue 4, p.714-26, (2013) Read More / View Supplemental Materials
Abstract
2012
Comprehensive genomic characterization of squamous cell lung cancers.The Cancer Genome Atlas Research, Network, institution.)(Participants are arranged by area of contribution and then by, Genome sequencing centres: Broad Institute, Hammerman PS, Lawrence MS, Voet D., Jing R., Cibulskis K., Sivachenko A., Stojanov P., McKenna A., Lander E. S., Gabriel S., Getz G., Sougnez C., Imielinski M., Helman E., Hernandez B., Pho NH, Meyerson M., et al. Nature, 2012/09/09, (2012) Read More / View Supplemental Materials
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Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia.Brown, JR, Hanna M., Tesar B., Werner L., Pochet N., Asara JM, Wang YE, Dal Cin P., Fernandes SM, Thompson C., MacConaill L., Wu CJ, Van de Peer Y., Correll M., Regev A., Neuberg D., and Freedman AS Clinical cancer research : an official journal of the American Association for Cancer Research, 2012/06/13, (2012) Read More / View Supplemental Materials
Abstract
2011
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia.Wang, L., Lawrence MS, Wan Y., Stojanov P., Sougnez C., Stevenson K., Werner L., Sivachenko A., Deluca DS, Zhang L., Zhang W., Vartanov AR, Fernandes SM, Goldstein NR, Folco EG, Cibulskis K., Tesar B., Sievers QL, Shefler E., Gabriel S., et al. The New England journal of medicine, 2011/12/29, Volume 365, Issue 26, p.2497-506, (2011) Read More / View Supplemental Materials
Abstract
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.Ding, Z., Wu CJ, Chu GC, Xiao Y., Ho D., Zhang J., Perry SR, Labrot ES, Wu X., Lis R., Hoshida Y., Hiller D., Hu B., Jiang S., Zheng H., Stegh AH, Scott KL, Signoretti S., Bardeesy N., Wang YA, et al. Nature, 2011/02/10, Volume 470, Issue 7333, p.269-73, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-29 of 29 Results