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  • Showing 1-22 of 22 Results
2012
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.Imielinski, M., Berger AH, Hammerman PS, Hernandez B., Pugh TJ, Hodis E., Cho J., Suh J., Capelletti M., Sivachenko A., Sougnez C., Auclair D., Lawrence MS, Stojanov P., Cibulskis K., Choi K., de Waal L., Sharifnia T., Brooks A., Greulich H., et al. Cell, 2012/09/14, Volume 150, Issue 6, p.1107-20, (2012) Read More / View Supplemental Materials
Abstract
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.Greulich, H., Kaplan B., Mertins P., Chen TH, Tanaka KE, Yun CH, Zhang X., Lee SH, Cho J., Ambrogio L., Liao R., Imielinski M., Banerji S., Berger AH, Lawrence MS, Zhang J., Pho NH, Walker SR, Winckler W., Getz G., et al. Proceedings of the National Academy of Sciences of the United States of America, 2012/09/04, Volume 109, Issue 36, p.14476-81, (2012) Read More / View Supplemental Materials
Abstract
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations.Pugh, TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D., Bochicchio J., Carneiro MO, Carter SL, Cibulskis K., Erlich RL, Greulich H., Lawrence MS, Lennon NJ, McKenna A., Meldrim J., Ramos AH, Ross MG, Russ C., Shefler E., Sivachenko A., et al. Nature, 2012/08/02, Volume 488, Issue 7409, p.106-10, (2012) Read More / View Supplemental Materials
Abstract
2011
Targeting mutant fibroblast growth factor receptors in cancer.Greulich, H., and Pollock PM Trends in molecular medicine, 2011/05/01, Volume 17, Issue 5, p.283-92, (2011) Read More / View Supplemental Materials
Abstract
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.Cho, YJ, Tsherniak A., Tamayo P., Santagata S., Ligon A., Greulich H., Berhoukim R., Amani V., Goumnerova L., Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A., Delattre O., Kool M., Ligon K., Meyerson M., Mesirov J. P., and Pomeroy SL Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/04/10, Volume 29, Issue 11, p.1424-30, (2011) Read More / View Supplemental Materials
Abstract
Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features.Tamayo, P., Cho YJ, Tsherniak A., Greulich H., Ambrogio L., Schouten-van Meeteren N., Zhou T., Buxton A., Kool M., Meyerson M., Pomeroy SL, and Mesirov J. P. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/04/10, Volume 29, Issue 11, p.1415-23, (2011) Read More / View Supplemental Materials
Abstract
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer.Dutt, A., Ramos AH, Hammerman PS, Mermel C., Cho J., Sharifnia T., Chande A., Tanaka KE, Stransky N., Greulich H., Gray NS, and Meyerson M. PloS one, 2011/01/01, Volume 6, Issue 6, p.e20351, (2011) Read More / View Supplemental Materials
Abstract
2010
The genomics of lung adenocarcinoma: opportunities for targeted therapies.Greulich, H. Genes & cancer, 2010/12/01, Volume 1, Issue 12, p.1200-10, (2010) Read More / View Supplemental Materials
Abstract
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.Barretina, J., Taylor BS, Banerji S., Ramos AH, Lagos-Quintana M., Decarolis PL, Shah K., Socci ND, Weir BA, Ho A., Chiang DY, Reva B., Mermel CH, Getz G., Antipin Y., Beroukhim R., Major JE, Hatton C., Nicoletti R., Hanna M., et al. Nature genetics, 2010/08/01, Volume 42, Issue 8, p.715-21, (2010) Read More / View Supplemental Materials
Abstract
The landscape of somatic copy-number alteration across human cancers.Beroukhim, R., Mermel CH, Porter D., Wei G., Raychaudhuri S., Donovan J., Barretina J., Boehm JS, Dobson J., Urashima M., Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L., Greulich H., Reich M., Winckler W., Lawrence MS, Weir BA, et al. Nature, 2010/02/18, Volume 463, Issue 7283, p.899-905, (2010) Read More / View Supplemental Materials
Abstract
2009
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation.Salvesen, HB, Carter SL, Mannelqvist M., Dutt A., Getz G., Stefansson IM, Raeder MB, Sos ML, Engelsen IB, Trovik J., Wik E., Greulich H., Bø TH, Jonassen I., Thomas RK, Zander T., Garraway LA, Oyan AM, Sellers WR, Kalland KH, et al. Proceedings of the National Academy of Sciences of the United States of America, 2009/03/24, Volume 106, Issue 12, p.4834-9, (2009) Read More / View Supplemental Materials
Abstract
2008
Somatic mutations affect key pathways in lung adenocarcinoma.Ding, L., Getz G., Wheeler DA, Mardis ER, McLellan MD, Cibulskis K., Sougnez C., Greulich H., Muzny DM, Morgan MB, Fulton L., Fulton RS, Zhang Q., Wendl MC, Lawrence MS, Larson DE, Chen K., Dooling DJ, Sabo A., Hawes AC, et al. Nature, 2008/10/23, Volume 455, Issue 7216, p.1069-75, (2008) Read More / View Supplemental Materials
Abstract
Activating mutations in ALK provide a therapeutic target in neuroblastoma.George, RE, Sanda T., Hanna M., Fröhling S., Luther W 2nd, Zhang J., Ahn Y., Zhou W., London WB, McGrady P., Xue L., Zozulya S., Gregor VE, Webb TR, Gray NS, Gilliland DG, Diller L., Greulich H., Morris SW, Meyerson M., et al. Nature, 2008/10/16, Volume 455, Issue 7215, p.975-8, (2008) Read More / View Supplemental Materials
Abstract
Drug-sensitive FGFR2 mutations in endometrial carcinoma.Dutt, A., Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C., Nicoletti R., Winckler W., Grewal R., Hanna M., Wyhs N., Ziaugra L., Richter DJ, Trovik J., Engelsen IB, Stefansson IM, Fennell T., Cibulskis K., Zody MC, Akslen LA, et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/06/24, Volume 105, Issue 25, p.8713-7, (2008) Read More / View Supplemental Materials
Abstract
Modeling genomic diversity and tumor dependency in malignant melanoma.Lin, WM, Baker AC, Beroukhim R., Winckler W., Feng W., Marmion JM, Laine E., Greulich H., Tseng H., Gates C., Hodi FS, Dranoff G., Sellers WR, Thomas RK, Meyerson M., Golub T. R., Dummer R., Herlyn M., Getz G., and Garraway LA Cancer research, 2008/02/01, Volume 68, Issue 3, p.664-73, (2008) Read More / View Supplemental Materials
Abstract
Probing the cancer genome.Greulich, H. Genome biology, 2008/01/01, Volume 9, Issue 5, p.309, (2008) Read More / View Supplemental Materials
2007
Characterizing the cancer genome in lung adenocarcinoma.Weir, BA, Woo MS, Getz G., Perner S., Ding L., Beroukhim R., Lin WM, Province MA, Kraja A., Johnson LA, Shah K., Sato M., Thomas RK, Barletta JA, Borecki IB, Broderick S., Chang AC, Chiang DY, Chirieac LR, Cho J., et al. Nature, 2007/12/06, Volume 450, Issue 7171, p.893-8, (2007) Read More / View Supplemental Materials
Abstract
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.Boehm, JS, Zhao JJ, Yao J., Kim SY, Firestein R., Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S., Richardson AL, Greulich H., Stewart CJ, Mulvey LA, Shen RR, Ambrogio L., Hirozane-Kishikawa T., Hill DE, Vidal M., Meyerson M., Grenier JK, et al. Cell, 2007/06/15, Volume 129, Issue 6, p.1065-79, (2007) Read More / View Supplemental Materials
Abstract
High-throughput oncogene mutation profiling in human cancer.Thomas, RK, Baker AC, Debiasi RM, Winckler W., LaFramboise T., Lin WM, Wang M., Feng W., Zander T., MacConaill L., Lee JC, Nicoletti R., Hatton C., Goyette M., Girard L., Majmudar K., Ziaugra L., Wong KK, Gabriel S., Beroukhim R., et al. Nature genetics, 2007/03/01, Volume 39, Issue 3, p.347-51, (2007) Read More / View Supplemental Materials
Abstract
2006
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.Lee, JC, Vivanco I., Beroukhim R., Huang JH, Feng WL, Debiasi RM, Yoshimoto K., King JC, Nghiemphu P., Yuza Y., Xu Q., Greulich H., Thomas RK, Paez JG, Peck TC, Linhart DJ, Glatt KA, Getz G., Onofrio R., Ziaugra L., et al. PLoS medicine, 2006/12/01, Volume 3, Issue 12, p.e485, (2006) Read More / View Supplemental Materials
Abstract
2005
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants.Greulich, H., Chen TH, Feng W., Jänne PA, Alvarez JV, Zappaterra M., Bulmer SE, Frank DA, Hahn WC, Sellers WR, and Meyerson M. PLoS medicine, 2005/11/01, Volume 2, Issue 11, p.e313, (2005) Read More / View Supplemental Materials
Abstract
2004
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.Paez, JG, Jänne PA, Lee JC, Tracy S., Greulich H., Gabriel S., Herman P., Kaye FJ, Lindeman N., Boggon TJ, Naoki K., Sasaki H., Fujii Y., Eck MJ, Sellers WR, Johnson B. E., and Meyerson M. Science (New York, N.Y.), 2004/06/04, Volume 304, Issue 5676, p.1497-500, (2004) Read More / View Supplemental Materials
Abstract
  • Showing 1-22 of 22 Results