Recent Broad Publications

Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.
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Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.
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Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.
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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.
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miR-155 in Acute Myeloid Leukemia: Not Merely a Prognostic Marker?
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Scientific Publications

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Found 11 results

Filters: Author is Smith, ZD [Clear All Filters]

2013

DNA methylation: roles in mammalian development.Smith, ZD, and Meissner A. Nature reviews. Genetics, 2013/02/12, Volume 14, Issue 3, p.204-20, (2013) Read More / View Supplemental Materials

The simplest explanation: passive DNA demethylation in PGCs.Smith, ZD, and Meissner A. The EMBO journal, 2013/02/06, Volume 32, Issue 3, p.318-21, (2013) Read More / View Supplemental Materials

2012

Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling.Boyle, P., Clement K., Gu H., Smith ZD, Ziller M., Fostel JL, Holmes L., Meldrim J., Kelley F., Gnirke A., and Meissner A. Genome biology, 2012/10/03, Volume 13, Issue 10, p.R92, (2012) Read More / View Supplemental Materials

Mouse ooplasm confers context-specific reprogramming capacity.Chan, MM, Smith ZD, Egli D., Regev A., and Meissner A. Nature genetics, 2012/09/01, Volume 44, Issue 9, p.978-80, (2012) Read More / View Supplemental Materials

DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells.Bock, C., Beerman I., Lien WH, Smith ZD, Gu H., Boyle P., Gnirke A., Fuchs E., Rossi DJ, and Meissner A. Molecular cell, 2012/08/24, Volume 47, Issue 4, p.633-47, (2012) Read More / View Supplemental Materials

A unique regulatory phase of DNA methylation in the early mammalian embryo.Smith, ZD, Chan MM, Mikkelsen TS, Gu H., Gnirke A., Regev A., and Meissner A. Nature, 2012/03/28, Volume 484, Issue 7394, p.339-44, (2012) Read More / View Supplemental Materials

2011

Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling.Gu, H., Smith ZD, Bock C., Boyle P., Gnirke A., and Meissner A. Nature protocols, 2011/04/01, Volume 6, Issue 4, p.468-81, (2011) Read More / View Supplemental Materials

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.Bock, C., Kiskinis E., Verstappen G., Gu H., Boulting G., Smith ZD, Ziller M., Croft GF, Amoroso MW, Oakley DH, Gnirke A., Eggan K., and Meissner A. Cell, 2011/02/04, Volume 144, Issue 3, p.439-52, (2011) Read More / View Supplemental Materials

Reprogramming factor expression initiates widespread targeted chromatin remodeling.Koche, RP, Smith ZD, Adli M., Gu H., Ku M., Gnirke A., Bernstein BE, and Meissner A. Cell stem cell, 2011/01/07, Volume 8, Issue 1, p.96-105, (2011) Read More / View Supplemental Materials

2010

Dynamic single-cell imaging of direct reprogramming reveals an early specifying event.Smith, ZD, Nachman I., Regev A., and Meissner A. Nature biotechnology, 2010/05/01, Volume 28, Issue 5, p.521-6, (2010) Read More / View Supplemental Materials

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution.Gu, H., Bock C., Mikkelsen TS, Jäger N., Smith ZD, Tomazou E., Gnirke A., Lander E. S., and Meissner A. Nature methods, 2010/02/01, Volume 7, Issue 2, p.133-6, (2010) Read More / View Supplemental Materials