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  • Showing 1-10 of 10 Results
2013
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.Gerard, B., Lee MD 4th, Dandapani S., Duvall JR, Fitzgerald ME, Kesavan S., Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M., Hamann D., Lemercier B., Murillo T., Akella LB, Foley MA, and Marcaurelle LA The Journal of organic chemistry, 2013/06/07, Volume 78, Issue 11, p.5160-71, (2013) Read More / View Supplemental Materials
Abstract
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.Mulrooney, CA, Lahr DL, Quintin MJ, Youngsaye W., Moccia D., Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P., Bittker JA, Clemons PA, Brudz S., Dandapani S., Duvall JR, Tolliday NJ, and De Souza A. Journal of computer-aided molecular design, 2013/04/13, (2013) Read More / View Supplemental Materials
Abstract
2012
Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahydroquinoline Library.Gerard, B., O'Shea MW, Donckele E., Kesavan S., Akella LB, Xu H., Jacobsen EN, and Marcaurelle LA ACS combinatorial science, 2012/10/22, (2012) Read More / View Supplemental Materials
Abstract
Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries.Lowe, JT, Lee MD 4th, Akella LB, Davoine E., Donckele EJ, Durak L., Duvall JR, Gerard B., Holson EB, Joliton A., Kesavan S., Lemercier BC, Liu H., Marié JC, Mulrooney CA, Muncipinto G., Welzel-O'Shea M., Panko LM, Rowley A., Suh BC, et al. The Journal of organic chemistry, 2012/08/10, (2012) Read More / View Supplemental Materials
Abstract
Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization.Fitzgerald, ME, Mulrooney CA, Duvall JR, Wei J., Suh BC, Akella LB, Vrcic A., and Marcaurelle LA ACS combinatorial science, 2012/02/13, Volume 14, Issue 2, p.89-96, (2012) Read More / View Supplemental Materials
Abstract
2011
Application of a sparse matrix design strategy to the synthesis of dos libraries.Akella, LB, and Marcaurelle LA ACS combinatorial science, 2011/07/11, Volume 13, Issue 4, p.357-64, (2011) Read More / View Supplemental Materials
Abstract
Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via S(N)Ar cycloetherification.Gerard, B., Duvall JR, Lowe JT, Murillo T., Wei J., Akella LB, and Marcaurelle LA ACS combinatorial science, 2011/07/11, Volume 13, Issue 4, p.365-74, (2011) Read More / View Supplemental Materials
Abstract
Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles.Comer, E., Liu H., Joliton A., Clabaut A., Johnson C., Akella LB, and Marcaurelle LA Proceedings of the National Academy of Sciences of the United States of America, 2011/04/26, Volume 108, Issue 17, p.6751-6, (2011) Read More / View Supplemental Materials
Abstract
2010
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Marcaurelle, LA, Comer E., Dandapani S., Duvall JR, Gerard B., Kesavan S., Lee MD 4th, Liu H., Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A., Ryba TD, Suh BC, Wei J., Young DW, Akella LB, Ross NT, Zhang YL, et al. Journal of the American Chemical Society, 2010/12/01, Volume 132, Issue 47, p.16962-76, (2010) Read More / View Supplemental Materials
Abstract
Cheminformatics approaches to analyze diversity in compound screening libraries.Akella, LB, and DeCaprio D. Current opinion in chemical biology, 2010/06/01, Volume 14, Issue 3, p.325-30, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-10 of 10 Results