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2014
Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance.Lukens, AK, Ross LS, Heidebrecht R., Javier Gamo F., Lafuente-Monasterio MJ, Booker ML, Hartl DL, Wiegand RC, and Wirth DF Proceedings of the National Academy of Sciences of the United States of America, 2014/01/14, Volume 111, Issue 2, p.799-804, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetic Surveillance Detects Both Clonal and Epidemic Transmission of Malaria following Enhanced Intervention in Senegal.Daniels, R., Chang HH, Séne PD, Park DC, Neafsey DE, Schaffner SF, Hamilton EJ, Lukens AK, Van Tyne D., Mboup S., Sabeti PC, Ndiaye D., Wirth DF, Hartl DL, and Volkman SK PloS one, 2013/01/01, Volume 8, Issue 4, p.e60780, (2013) Read More / View Supplemental Materials
Abstract
2012
Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite.Park, DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C., Ribacke U., Van Tyne D., Galinsky K., Galligan M., Becker JS, Ndiaye D., Mboup S., Wiegand RC, Hartl DL, Sabeti PC, Wirth DF, and Volkman SK Proceedings of the National Academy of Sciences of the United States of America, 2012/08/07, Volume 109, Issue 32, p.13052-7, (2012) Read More / View Supplemental Materials
Abstract
Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria.Heidebrecht RW, Jr, Mulrooney C., Austin CP, Barker RH Jr, Beaudoin JA, Cheng KC, Comer E., Dandapani S., Dick J., Duvall JR, Ekland EH, Fidock DA, Fitzgerald ME, Foley M., Guha R., Hinkson P., Kramer M., Lukens AK, Masi D., Marcaurelle LA, et al. ACS medicinal chemistry letters, 2012/02/09, Volume 3, Issue 2, p.112-117, (2012) Read More / View Supplemental Materials
Abstract
2011
Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.Van Tyne, D., Park DJ, Schaffner SF, Neafsey DE, Angelino E., Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA Jr, Johnson CA, Shlyakhter I., Grossman SR, Becker JS, Yamins D., Karlsson EK, Ndiaye D., Sarr O., Mboup S., et al. PLoS genetics, 2011/04/01, Volume 7, Issue 4, p.e1001383, (2011) Read More / View Supplemental Materials
Abstract
2010
ML238: An Antimalarial Small Molecule of a Unique Structural ClassWeiwer, M., Mulrooney C., Massi D., Heidebrecht R., Wiegand R., Lukens AK, Dick J., Wirth D., Ekland E., Cheng CC, Zhao J., Yuan J., Su XZ, Johnson RL, Guha R., Dandapani S., Munoz B., Palmer M., Thomas C., Austin CP, et al., 2010/01/01, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-6 of 6 Results