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  • Showing 1-16 of 16 Results
2014
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.Wawer, MJ, Li K., Gustafsdottir SM, Ljosa V., Bodycombe NE, Marton MA, Sokolnicki KL, Bray MA, Kemp MM, Winchester E., Taylor B., Grant GB, Hon CS, Duvall JR, Wilson JA, Bittker JA, Dančík V., Narayan R., Subramanian A., Winckler W., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/07/14, (2014) Read More / View Supplemental Materials
Abstract
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.Duan, Q., Flynn C., Niepel M., Hafner M., Muhlich JL, Fernandez NF, Rouillard AD, Tan CM, Chen EY, Golub T. R., Sorger PK, Subramanian A., and Ma'ayan A. Nucleic acids research, 2014/06/06, (2014) Read More / View Supplemental Materials
Abstract
2011
Molecular signatures database (MSigDB) 3.0.Liberzon, A., Subramanian A., Pinchback R., Thorvaldsdóttir H., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2011/06/15, Volume 27, Issue 12, p.1739-40, (2011) Read More / View Supplemental Materials
Abstract
Densely interconnected transcriptional circuits control cell states in human hematopoiesis.Novershtern, N., Subramanian A., Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N., Yosef N., Chang CY, Shay T., Frampton GM, Drake AC, Leskov I., Nilsson B., Preffer F., Dombkowski D., Evans JW, Liefeld T., Smutko JS, Chen J., et al. Cell, 2011/01/21, Volume 144, Issue 2, p.296-309, (2011) Read More / View Supplemental Materials
Abstract
Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes.Shaw, SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A., and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2011/01/11, Volume 108, Issue 2, p.492-7, (2011) Read More / View Supplemental Materials
Abstract
2008
Highly parallel identification of essential genes in cancer cells.Luo, B., Cheung HW, Subramanian A., Sharifnia T., Okamoto M., Yang X., Hinkle G., Boehm JS, Beroukhim R., Weir BA, Mermel C., Barbie DA, Awad T., Zhou X., Nguyen T., Piqani B., Li C., Golub T. R., Meyerson M., Hacohen N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/12/23, Volume 105, Issue 51, p.20380-5, (2008) Read More / View Supplemental Materials
Abstract
Perturbational profiling of nanomaterial biologic activity.Shaw, SY, Westly EC, Pittet MJ, Subramanian A., Schreiber SL, and Weissleder R. Proceedings of the National Academy of Sciences of the United States of America, 2008/05/27, Volume 105, Issue 21, p.7387-92, (2008) Read More / View Supplemental Materials
Abstract
2007
GSEA-P: a desktop application for Gene Set Enrichment Analysis.Subramanian, A., Kuehn H., Gould J., Tamayo P., and Mesirov J. P. Bioinformatics (Oxford, England), 2007/12/01, Volume 23, Issue 23, p.3251-3, (2007) Read More / View Supplemental Materials
Abstract
IFN-alpha-stimulated genes and Epstein-Barr virus gene expression distinguish WHO type II and III nasopharyngeal carcinomas.Pegtel, DM, Subramanian A., Meritt D., Tsai CH, Sheen TS, Golub T. R., and Thorley-Lawson DA Cancer research, 2007/01/15, Volume 67, Issue 2, p.474-81, (2007) Read More / View Supplemental Materials
Abstract
2006
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.Lamb, J., Crawford ED, Peck D., Modell JW, Blat IC, Wrobel MJ, Lerner J., Brunet JP, Subramanian A., Ross KN, Reich M., Hieronymus H., Wei G., Armstrong SA, Haggarty SJ, Clemons PA, Wei R., Carr SA, Lander E. S., and Golub T. R. Science (New York, N.Y.), 2006/09/29, Volume 313, Issue 5795, p.1929-35, (2006) Read More / View Supplemental Materials
Abstract
Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.Bourquin, JP, Subramanian A., Langebrake C., Reinhardt D., Bernard O., Ballerini P., Baruchel A., Cavé H., Dastugue N., Hasle H., Kaspers GL, Lessard M., Michaux L., Vyas P., van Wering E., Zwaan CM, Golub T. R., and Orkin SH Proceedings of the National Academy of Sciences of the United States of America, 2006/02/28, Volume 103, Issue 9, p.3339-44, (2006) Read More / View Supplemental Materials
Abstract
2005
Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasis.Pegtel, DM, Subramanian A., Sheen TS, Tsai CH, Golub T. R., and Thorley-Lawson DA Journal of virology, 2005/12/01, Volume 79, Issue 24, p.15430-42, (2005) Read More / View Supplemental Materials
Abstract
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.Subramanian, A., Tamayo P., Mootha VK, Mukherjee S., Ebert BL, Gillette MA, Paulovich A., Pomeroy SL, Golub T. R., Lander E. S., and Mesirov J. P. Proceedings of the National Academy of Sciences of the United States of America, 2005/10/25, Volume 102, Issue 43, p.15545-50, (2005) Read More / View Supplemental Materials
Abstract
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.Shepard, JL, Amatruda JF, Stern HM, Subramanian A., Finkelstein D., Ziai J., Finley KR, Pfaff KL, Hersey C., Zhou Y., Barut B., Freedman M., Lee C., Spitsbergen J., Neuberg D., Weber G., Golub T. R., Glickman JN, Kutok JL, Aster J. C., et al. Proceedings of the National Academy of Sciences of the United States of America, 2005/09/13, Volume 102, Issue 37, p.13194-9, (2005) Read More / View Supplemental Materials
Abstract
An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray.Ebert, BL, Lee MM, Pretz JL, Subramanian A., Mak R., Golub T. R., and Sieff CA Blood, 2005/06/15, Volume 105, Issue 12, p.4620-6, (2005) Read More / View Supplemental Materials
Abstract
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.Sweet-Cordero, A., Mukherjee S., Subramanian A., You H., Roix JJ, Ladd-Acosta C., Mesirov J., Golub T. R., and Jacks T. Nature genetics, 2005/01/01, Volume 37, Issue 1, p.48-55, (2005) Read More / View Supplemental Materials
Abstract
  • Showing 1-16 of 16 Results