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  • Showing 1-11 of 11 Results
2014
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.Wawer, MJ, Li K., Gustafsdottir SM, Ljosa V., Bodycombe NE, Marton MA, Sokolnicki KL, Bray MA, Kemp MM, Winchester E., Taylor B., Grant GB, Hon CS, Duvall JR, Wilson JA, Bittker JA, Dančík V., Narayan R., Subramanian A., Winckler W., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/07/14, (2014) Read More / View Supplemental Materials
Abstract
Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses.Dancík, V., Carrel H., Bodycombe NE, Seiler KP, Fomina-Yadlin D., Kubicek ST, Hartwell K., Shamji AF, Wagner BK, and Clemons PA Journal of biomolecular screening, 2014/01/24, (2014) Read More / View Supplemental Materials
Abstract
2013
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.Basu, A., Bodycombe NE, Cheah JH, Price EV, Liu K., Schaefer GI, Ebright RY, Stewart ML, Ito D., Wang S., Bracha AL, Liefeld T., Wawer M., Gilbert JC, Wilson AJ, Stransky N., Kryukov GV, Dancik V., Barretina J., Garraway LA, et al. Cell, 2013/08/29, Volume 154, Issue 5, p.1151-61, (2013) Read More / View Supplemental Materials
Abstract
2012
Utility-aware screening with clique-oriented prioritization.Swamidass, SJ, Calhoun BT, Bittker JA, Bodycombe NE, and Clemons PA Journal of chemical information and modeling, 2012/01/23, Volume 52, Issue 1, p.29-37, (2012) Read More / View Supplemental Materials
Abstract
2011
Master Data Management: Getting your House in Order.Seiler, KP, Bodycombe NE, Hawkins T., Shell R., Lemon A., Souza A., and Clemons PA Combinatorial chemistry & high throughput screening, 2011/11/01, Volume 14, Issue 9, p.749-56, (2011) Read More / View Supplemental Materials
Abstract
A small-molecule screening strategy to identify suppressors of statin myopathy.Wagner, BK, Gilbert TJ, Hanai J., Imamura S., Bodycombe NE, Bon RS, Waldmann H., Clemons PA, Sukhatme VP, and Mootha VK ACS chemical biology, 2011/09/16, Volume 6, Issue 9, p.900-4, (2011) Read More / View Supplemental Materials
Abstract
Enhancing the rate of scaffold discovery with diversity-oriented prioritization.Swamidass, SJ, Calhoun BT, Bittker JA, Bodycombe NE, and Clemons PA Bioinformatics (Oxford, England), 2011/08/15, Volume 27, Issue 16, p.2271-8, (2011) Read More / View Supplemental Materials
Abstract
2010
Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles.Clemons, PA, Bodycombe NE, Carrinski HA, Wilson JA, Shamji AF, Wagner BK, Koehler AN, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2010/11/02, Volume 107, Issue 44, p.18787-92, (2010) Read More / View Supplemental Materials
Abstract
Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis.Chou, DH, Bodycombe NE, Carrinski HA, Lewis TA, Clemons PA, Schreiber SL, and Wagner BK ACS chemical biology, 2010/08/20, Volume 5, Issue 8, p.729-34, (2010) Read More / View Supplemental Materials
Abstract
An economic framework to prioritize confirmatory tests after a high-throughput screen.Swamidass, SJ, Bittker JA, Bodycombe NE, Ryder SP, and Clemons PA Journal of biomolecular screening, 2010/07/01, Volume 15, Issue 6, p.680-6, (2010) Read More / View Supplemental Materials
Abstract
2008
ChemBank: a small-molecule screening and cheminformatics resource database.Seiler, KP, George GA, Happ MP, Bodycombe NE, Carrinski HA, Norton S., Brudz S., Sullivan JP, Muhlich J., Serrano M., Ferraiolo P., Tolliday NJ, Schreiber SL, and Clemons PA Nucleic acids research, 2008/01/01, Volume 36, p.D351-9, (2008) Read More / View Supplemental Materials
Abstract
  • Showing 1-11 of 11 Results