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  • Showing 1-13 of 13 Results
2014
Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.Sundberg, TB, Choi HG, Song JH, Russell CN, Hussain MM, Graham DB, Khor B., Gagnon J., O'Connell DJ, Narayan K., Dančík V., Perez JR, Reinecker HC, Gray NS, Schreiber SL, Xavier RJ, and Shamji AF Proceedings of the National Academy of Sciences of the United States of America, 2014/08/11, (2014) Read More / View Supplemental Materials
Abstract
Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine.Wurst, JM, Drake EJ, Theriault JR, Jewett IT, VerPlank L., Perez JR, Dandapani S., Palmer M., Moskowitz SM, Schreiber SL, Munoz B., and Gulick AM ACS chemical biology, 2014/05/21, (2014) Read More / View Supplemental Materials
Abstract
Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease.Dandapani, S., Germain AR, Jewett I., le Quement S., Marie JC, Muncipinto G., Duvall JR, Carmody LC, Perez JR, Engel JC, Gut J., Kellar D., Siqueira-Neto JL, McKerrow JH, Kaiser M., Rodriguez A., Palmer MA, Foley M., Schreiber SL, and Munoz B. ACS medicinal chemistry letters, 2014/02/13, Volume 5, Issue 2, p.149-53, (2014) Read More / View Supplemental Materials
Abstract
2013
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.Germain, AR, Carmody LC, Nag PP, Morgan B., VerPlank L., Fernandez C., Donckele E., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2013/03/15, Volume 23, Issue 6, p.1834-8, (2013) Read More / View Supplemental Materials
Abstract
2012
Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies.Dockendorff, C., Nagiec MM, Weïwer M., Buhrlage S., Ting A., Nag PP, Germain A., Kim HJ, Youngsaye W., Scherer C., Bennion M., Xue L., Stanton BZ, Lewis TA, Macpherson L., Palmer M., Foley MA, Perez JR, and Schreiber SL ACS medicinal chemistry letters, 2012/10/11, Volume 3, Issue 10, p.808-813, (2012) Read More / View Supplemental Materials
Abstract
Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cells.Carmody, LC, Germain AR, VerPlank L., Nag PP, Muñoz B., Perez JR, and Palmer MA Journal of biomolecular screening, 2012/10/01, Volume 17, Issue 9, p.1204-10, (2012) Read More / View Supplemental Materials
Abstract
Identification of a selective small molecule inhibitor of breast cancer stem cells.Germain, AR, Carmody LC, Morgan B., Fernandez C., Forbeck E., Lewis TA, Nag PP, Ting A., VerPlank L., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/05/15, Volume 22, Issue 10, p.3571-4, (2012) Read More / View Supplemental Materials
Abstract
Chemical Genetic Analysis of Platelet Granule Secretion-Probe 1VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Chemical Genetic Analysis of Platelet Granule Secretion-Probe 2VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Chemical Genetic Analysis of Platelet Granule Secretion-Probe 3VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 1An, WF, Metkar SR, Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 2An, WF, Metkar SR, Lewis TA, Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 3An, WF, Metkar SR, Youngsaye W., Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-13 of 13 Results