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2014
Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Can Mediate Neuroprotection Independent of HDAC Inhibition.Sleiman, SF, Olson DE, Bourassa MW, Karuppagounder SS, Zhang YL, Gale J., Wagner FF, Basso M., Coppola G., Pinto JT, Holson EB, and Ratan RR The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014/10/22, Volume 34, Issue 43, p.14328-37, (2014) Read More / View Supplemental Materials
Abstract
An unbiased approach to identify endogenous substrates of "histone" deacetylase 8.Olson, DE, Udeshi ND, Wolfson NA, Pitcairn CA, Sullivan ED, Jaffe JD, Svinkina T., Natoli T., Lu X., Paulk J., McCarren P., Wagner FF, Barker D., Howe E., Lazzaro F., Gale JP, Zhang YL, Subramanian A., Fierke CA, Carr SA, et al. ACS chemical biology, 2014/10/17, Volume 9, Issue 10, p.2210-6, (2014) Read More / View Supplemental Materials
Abstract
Selective HDAC inhibition for the disruption of latent HIV-1 infection.Barton, KM, Archin NM, Keedy KS, Espeseth AS, Zhang YL, Gale J., Wagner FF, Holson EB, and Margolis DM PloS one, 2014/01/01, Volume 9, Issue 8, p.e102684, (2014) Read More / View Supplemental Materials
Abstract
2013
Discovery of the first histone deacetylase 6/8 dual inhibitors.Olson, DE, Wagner FF, Kaya T., Gale JP, Aidoud N., Davoine EL, Lazzaro F., Weïwer M., Zhang YL, and Holson EB Journal of medicinal chemistry, 2013/06/13, Volume 56, Issue 11, p.4816-20, (2013) Read More / View Supplemental Materials
Abstract
Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif.Wagner, FF, Olson DE, Gale JP, Kaya T., Weïwer M., Aidoud N., Thomas M., Davoine EL, Lemercier BC, Zhang YL, and Holson EB Journal of medicinal chemistry, 2013/02/18, (2013) Read More / View Supplemental Materials
Abstract
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.Schroeder, FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J., Zhao WN, Reis S., Barker DD, Berry-Scott E., Kim SW, Clore EL, Hooker JM, Holson EB, Haggarty SJ, and Petryshen TL PloS one, 2013/01/01, Volume 8, Issue 8, p.e71323, (2013) Read More / View Supplemental Materials
Abstract
2011
The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells.Wilson, AJ, Holson E., Wagner F., Zhang YL, Fass DM, Haggarty SJ, Bhaskara S., Hiebert SW, Schreiber SL, and Khabele D. Cancer biology & therapy, 2011/09/15, Volume 12, Issue 6, p.484-93, (2011) Read More / View Supplemental Materials
Abstract
2010
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Marcaurelle, LA, Comer E., Dandapani S., Duvall JR, Gerard B., Kesavan S., Lee MD 4th, Liu H., Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A., Ryba TD, Suh BC, Wei J., Young DW, Akella LB, Ross NT, Zhang YL, et al. Journal of the American Chemical Society, 2010/12/01, Volume 132, Issue 47, p.16962-76, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-8 of 8 Results