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2014
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.Perry, JA, Kiezun A., Tonzi P., Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E., Pedamallu CS, Helman E., Taylor-Weiner A., McKenna A., Deluca DS, Lawrence MS, Ambrogio L., Sougnez C., Sivachenko A., Walensky LD, Wagle N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
Abstract
In vivo discovery of immunotherapy targets in the tumour microenvironment.Zhou, P., Shaffer DR, Alvarez Arias DA, Nakazaki Y., Pos W., Torres AJ, Cremasco V., Dougan SK, Cowley GS, Elpek K., Brogdon J., Lamb J., Turley SJ, Ploegh HL, Root DE, Love JC, Dranoff G., Hacohen N., Cantor H., and Wucherpfennig KW Nature, 2014/02/06, Volume 506, Issue 7486, p.52-7, (2014) Read More / View Supplemental Materials
Abstract
The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection.Filone, CM, Caballero IS, Dower K., Mendillo ML, Cowley GS, Santagata S., Rozelle DK, Yen J., Rubins KH, Hacohen N., Root DE, Hensley LE, and Connor J. PLoS pathogens, 2014/02/01, Volume 10, Issue 2, p.e1003904, (2014) Read More / View Supplemental Materials
Abstract
2013
SQSTM1 Is a Pathogenic Target of 5q Copy Number Gains in Kidney Cancer.Li, L., Shen C., Nakamura E., Ando K., Signoretti S., Beroukhim R., Cowley GS, Lizotte P., Liberzon E., Bair S., Root DE, Tamayo P., Tsherniak A., Cheng SC, Tabak B., Jacobsen A., Hakimi AA, Schultz N., Ciriello G., Sander C., et al. Cancer cell, 2013/12/09, Volume 24, Issue 6, p.738-50, (2013) Read More / View Supplemental Materials
Abstract
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling.Miller, PG, Al-Shahrour F., Hartwell KA, Chu LP, Järås M., Puissant A., McConkey ME, Cowley GS, Shterental S., Alexe G., Armstrong SA, Root DE, Scadden DT, Hynes R. O., Mukherjee S., Stegmaier K., and Ebert BL Cancer cell, 2013/06/11, (2013) Read More / View Supplemental Materials
Abstract
A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition.Whittaker, SR, Theurillat JP, Van Allen E., Wagle N., Hsiao J., Cowley GS, Schadendorf D., Root DE, and Garraway LA Cancer discovery, 2013/01/03, (2013) Read More / View Supplemental Materials
Abstract
2012
β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis.Rosenbluh, J., Nijhawan D., Cox AG, Li X., Schafer EJ, Zack TI, Wang X., Tsherniak A., Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F., Cowley GS, Root DE, Mesirov J. P., Beroukhim R., and Hahn WC Cell, 2012/12/21, Volume 151, Issue 7, p.1457-73, (2012) Read More / View Supplemental Materials
Abstract
Cancer vulnerabilities unveiled by genomic loss.Nijhawan, D., Zack TI, Ren Y., Strickland MR, Lamothe R., Schumacher SE, Tsherniak A., Besche HC, Rosenbluh J., Shehata S., Cowley GS, Weir BA, Goldberg AL, Mesirov J. P., Root DE, Bhatia SN, Beroukhim R., and Hahn WC Cell, 2012/08/17, Volume 150, Issue 4, p.842-54, (2012) Read More / View Supplemental Materials
Abstract
Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4.Ren, Y., Cheung HW, von Maltzhan G., Agrawal A., Cowley GS, Weir BA, Boehm JS, Tamayo P., Karst AM, Liu JF, Hirsch MS, Mesirov J. P., Drapkin R., Root DE, Lo J., Fogal V., Ruoslahti E., Hahn WC, and Bhatia SN Science translational medicine, 2012/08/15, Volume 4, Issue 147, p.147ra112, (2012) Read More / View Supplemental Materials
Abstract
2011
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.Cheung, HW, Cowley GS, Weir BA, Boehm JS, Rusin S., Scott JA, East A., Ali LD, Lizotte PH, Wong TC, Jiang G., Hsiao J., Mermel CH, Getz G., Barretina J., Gopal S., Tamayo P., Gould J., Tsherniak A., Stransky N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2011/07/26, Volume 108, Issue 30, p.12372-7, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-10 of 10 Results