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  • Showing 1-10 of 10 Results
2016
Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling.Hwang, SY, Deng X., Byun S., Lee C., Lee SJ, Suh H., Zhang J., Kang Q., Zhang T., Westover KD, Mandinova A., and Lee SW Cell reports, 2016/06/16, (2016) Read More / View Supplemental Materials
Abstract
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Klionsky, DJ, Abdelmohsen K., Abe A., Abedin MJ, Abeliovich H., Acevedo Arozena A., Adachi H., Adams CM, Adams PD, Adeli K., Adhihetty PJ, Adler SG, Agam G., Agarwal R., Aghi MK, Agnello M., Agostinis P., Aguilar PV, Aguirre-Ghiso J., Airoldi EM, et al. Autophagy, 2016/01/02, Volume 12, Issue 1, p.1-222, (2016) Read More / View Supplemental Materials
2015
Sustained Akt activity is required to maintain cell viability in seborrheic keratosis, a benign epithelial tumor.Neel, VA, Todorova K., Wang J., Kwon E., Kang M., Liu Q., Gray N., Lee SW, and Mandinova A. The Journal of investigative dermatology, 2015/12/28, (2015) Read More / View Supplemental Materials
Abstract
Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2015/10/22, Volume 526, Issue 7574, p.596, (2015) Read More / View Supplemental Materials
Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.Hiraki, M., Hwang SY, Cao S., Ramadhar TR, Byun S., Yoon KW, Lee JH, Chu K., Gurkar AU, Kolev V., Zhang J., Namba T., Murphy ME, Newman DJ, Mandinova A., Clardy J., and Lee SW Chemistry & biology, 2015/08/27, (2015) Read More / View Supplemental Materials
Abstract
CELL DEATH. Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.Yoon, KW, Byun S., Kwon E., Hwang SY, Chu K., Hiraki M., Jo SH, Weins A., Hakroush S., Cebulla A., Sykes DB, Greka A., Mundel P., Fisher DE, Mandinova A., and Lee SW Science (New York, N.Y.), 2015/07/31, Volume 349, Issue 6247, p.1261669, (2015) Read More / View Supplemental Materials
Abstract
2014
Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach.Carr, SA, Abbatiello SE, Ackermann BL, Borchers C., Domon B., Deutsch EW, Grant RP, Hoofnagle AN, Hüttenhain R., Koomen JM, Liebler DC, Liu T., Maclean B., Mani D., Mansfield E., Neubert H., Paulovich AG, Reiter L., Vitek O., Aebersold R., et al. Molecular & cellular proteomics : MCP, 2014/03/01, Volume 13, Issue 3, p.907-17, (2014) Read More / View Supplemental Materials
Abstract
2012
Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells.Brown-Endres, L., Schoenfeld D., Tian F., Kim HG, Namba T., Muñoz-Fontela C., Mandinova A., Aaronson SA, and Lee SW Cancer research, 2012/05/01, Volume 72, Issue 9, p.2373-82, (2012) Read More / View Supplemental Materials
Abstract
2011
Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2011/07/13, Volume 475, Issue 7355, p.231-4, (2011) Read More / View Supplemental Materials
Abstract
2009
A small molecule that binds Hedgehog and blocks its signaling in human cells.Stanton, BZ, Peng LF, Maloof N., Nakai K., Wang X., Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A., and Schreiber SL Nature chemical biology, 2009/03/01, Volume 5, Issue 3, p.154-6, (2009) Read More / View Supplemental Materials
Abstract
  • Showing 1-10 of 10 Results