Recent Broad Publications
- Hopping between Differentiation States in Lung Adenocarcinoma.
Read More / View Supplemental Materials - Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
Read More / View Supplemental Materials - The Genome of Anopheles darlingi, the main neotropical malaria vector.
Read More / View Supplemental Materials - ATHLATES: accurate typing of human leukocyte antigen through exome sequencing.
Read More / View Supplemental Materials - Integrated proteomic analysis of post-translational modifications by serial enrichment.
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Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. The Journal of infectious diseases, 2011/08/15, Volume 204, Issue 4, p.609-16, (2011)
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Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog. Bioorganic & medicinal chemistry letters, 2009/11/15, Volume 19, Issue 22, p.6319-25, (2009)
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A small molecule that binds Hedgehog and blocks its signaling in human cells. Nature chemical biology, 2009/03/01, Volume 5, Issue 3, p.154-6, (2009)
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