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2011
Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase.Peng, LF, Schaefer EA, Maloof N., Skaff A., Berical A., Belon CA, Heck JA, Lin W., Frick DN, Allen TM, Miziorko HM, Schreiber SL, and Chung RT The Journal of infectious diseases, 2011/08/15, Volume 204, Issue 4, p.609-16, (2011) Read More / View Supplemental Materials
Abstract
2009
Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog.Peng, LF, Stanton BZ, Maloof N., Wang X., and Schreiber SL Bioorganic & medicinal chemistry letters, 2009/11/15, Volume 19, Issue 22, p.6319-25, (2009) Read More / View Supplemental Materials
Abstract
A small molecule that binds Hedgehog and blocks its signaling in human cells.Stanton, BZ, Peng LF, Maloof N., Nakai K., Wang X., Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A., and Schreiber SL Nature chemical biology, 2009/03/01, Volume 5, Issue 3, p.154-6, (2009) Read More / View Supplemental Materials
Abstract
  • Showing 1-3 of 3 Results