Scientific Publications

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.Bergen, SE, O'Dushlaine CT, Ripke S., Lee PH, Ruderfer DM, Akterin S., Moran JL, Chambert KD, Handsaker RE, Backlund L., Osby U., McCarroll S., Landen M., Scolnick EM, Magnusson PK, Lichtenstein P., Hultman CM, Purcell SM, Sklar P., and Sullivan PF Molecular psychiatry, 2012/06/12, (2012) Read More / View Supplemental Materials

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Abstract

AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics.Kuai, L., Ong SE, Madison JM, Wang X., Duvall JR, Lewis TA, Luce CJ, Conner SD, Pearlman DA, Wood JL, Schreiber SL, Carr SA, Scolnick EM, and Haggarty SJ Chemistry & biology, 2011/07/29, Volume 18, Issue 7, p.891-906, (2011) Read More / View Supplemental Materials

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Abstract

AKT kinase activity is required for lithium to modulate mood-related behaviors in mice.Pan, JQ, Lewis MC, Ketterman JK, Clore EL, Riley M., Richards KR, Berry-Scott E., Liu X., Wagner FF, Holson EB, Neve RL, Biechele TL, Moon RT, Scolnick EM, Petryshen TL, and Haggarty SJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011/06/01, Volume 36, Issue 7, p.1397-411, (2011) Read More / View Supplemental Materials

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Abstract

Chemical genetics identifies small-molecule modulators of neuritogenesis involving neuregulin-1/ErbB4 signaling.Kuai, L., Wang X., Madison JM, Schreiber SL, Scolnick EM, and Haggarty SJ ACS chemical neuroscience, 2010/01/28, Volume 1, Issue 4, p.325-342, (2010) Read More / View Supplemental Materials

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Abstract

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.Raychaudhuri, S., Plenge RM, Rossin EJ, Ng AC, International Schizophrenia Consortium, Purcell SM, Sklar P., Scolnick EM, Xavier RJ, Altshuler D., and Daly M. J. PLoS genetics, 2009/06/01, Volume 5, Issue 6, p.e1000534, (2009) Read More / View Supplemental Materials

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Abstract

Schizophrenia: do the genetics and neurobiology of neuregulin provide a pathogenesis model?Scolnick, EM, Petryshen T., and Sklar P. Harvard review of psychiatry, 2006/12/31, Volume 14, Issue 2, p.64-77, (2006) Read More / View Supplemental Materials

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Abstract

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.Mutsuddi, M., Morris DW, Waggoner SG, Daly M. J., Scolnick EM, and Sklar P. American journal of human genetics, 2006/11/01, Volume 79, Issue 5, p.903-9, (2006) Read More / View Supplemental Materials

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Abstract

Mechanisms of action of medicines for schizophrenia and bipolar illness: status and limitations.Scolnick, EM Biological psychiatry, 2006/06/01, Volume 59, Issue 11, p.1039-45, (2006) Read More / View Supplemental Materials

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Abstract