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  • Showing 1-15 of 15 Results
2014
De-Differentiation Confers Multidrug Resistance Via Noncanonical PERK-Nrf2 Signaling.Del Vecchio, CA, Feng Y., Sokol ES, Tillman EJ, Sanduja S., Reinhardt F., and Gupta PB PLoS biology, 2014/09/01, Volume 12, Issue 9, p.e1001945, (2014) Read More / View Supplemental Materials
Abstract
2013
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.Germain, AR, Carmody LC, Nag PP, Morgan B., VerPlank L., Fernandez C., Donckele E., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2013/03/15, Volume 23, Issue 6, p.1834-8, (2013) Read More / View Supplemental Materials
Abstract
2012
Identification of a selective small molecule inhibitor of breast cancer stem cells.Germain, AR, Carmody LC, Morgan B., Fernandez C., Forbeck E., Lewis TA, Nag PP, Ting A., VerPlank L., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/05/15, Volume 22, Issue 10, p.3571-4, (2012) Read More / View Supplemental Materials
Abstract
Chromatin-modifying enzymes as modulators of reprogramming.Onder, TT, Kara N., Cherry A., Sinha AU, Zhu N., Bernt KM, Cahan P., Marcarci BO, Unternaehrer J., Gupta PB, Lander E. S., Armstrong SA, and Daley GQ Nature, 2012/03/04, Volume 483, Issue 7391, p.598-602, (2012) Read More / View Supplemental Materials
Abstract
2011
Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells.Gupta, PB, Fillmore CM, Jiang G., Shapira SD, Tao K., Kuperwasser C., and Lander E. S. Cell, 2011/08/19, Volume 146, Issue 4, p.633-44, (2011) Read More / View Supplemental Materials
Abstract
Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.Proia, TA, Keller PJ, Gupta PB, Klebba I., Jones AD, Sedic M., Gilmore H., Tung N., Naber SP, Schnitt S., Lander E. S., and Kuperwasser C. Cell stem cell, 2011/02/04, Volume 8, Issue 2, p.149-63, (2011) Read More / View Supplemental Materials
Abstract
2010
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.Fillmore, CM, Gupta PB, Rudnick JA, Caballero S., Keller PJ, Lander E. S., and Kuperwasser C. Proceedings of the National Academy of Sciences of the United States of America, 2010/12/14, Volume 107, Issue 50, p.21737-42, (2010) Read More / View Supplemental Materials
Abstract
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes.Taube, JH, Herschkowitz JI, Komurov K., Zhou AY, Gupta S., Yang J., Hartwell K., Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander E. S., Rosen JM, Weinberg R. A., and Mani SA Proceedings of the National Academy of Sciences of the United States of America, 2010/08/31, Volume 107, Issue 35, p.15449-54, (2010) Read More / View Supplemental Materials
Abstract
2009
A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.Shapira, SD, Gat-Viks I., Shum BO, Dricot A., Degrace MM, Wu L., Gupta PB, Hao T., Silver SJ, Root DE, Hill DE, Regev A., and Hacohen N. Cell, 2009/12/24, Volume 139, Issue 7, p.1255-67, (2009) Read More / View Supplemental Materials
Abstract
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.Barbie, DA, Tamayo P., Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P., Meylan E., Scholl C., Fröhling S., Chan EM, Sos ML, Michel K., Mermel C., Silver SJ, Weir BA, Reiling JH, Sheng Q., Gupta PB, et al. Nature, 2009/11/05, Volume 462, Issue 7269, p.108-12, (2009) Read More / View Supplemental Materials
Abstract
Cancer stem cells: mirage or reality?Gupta, PB, Chaffer CL, and Weinberg R. A. Nature medicine, 2009/09/01, Volume 15, Issue 9, p.1010-2, (2009) Read More / View Supplemental Materials
Abstract
Identification of selective inhibitors of cancer stem cells by high-throughput screening.Gupta, PB, Onder TT, Jiang G., Tao K., Kuperwasser C., Weinberg R. A., and Lander E. S. Cell, 2009/08/21, Volume 138, Issue 4, p.645-59, (2009) Read More / View Supplemental Materials
Abstract
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.Vasudevan, KM, Barbie DA, Davies MA, Rabinovsky R., McNear CJ, Kim JJ, Hennessy BT, Tseng H., Pochanard P., Kim SY, Dunn IF, Schinzel AC, Sandy P., Hoersch S., Sheng Q., Gupta PB, Boehm JS, Reiling JH, Silver S., Lu Y., et al. Cancer cell, 2009/07/07, Volume 16, Issue 1, p.21-32, (2009) Read More / View Supplemental Materials
Abstract
2008
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.Onder, TT, Gupta PB, Mani SA, Yang J., Lander E. S., and Weinberg R. A. Cancer research, 2008/05/15, Volume 68, Issue 10, p.3645-54, (2008) Read More / View Supplemental Materials
Abstract
2006
Contributions of estrogen to ER-negative breast tumor growth.Gupta, PB, and Kuperwasser C. The Journal of steroid biochemistry and molecular biology, 2006/12/01, Volume 102, Issue 1-5, p.71-8, (2006) Read More / View Supplemental Materials
Abstract
  • Showing 1-15 of 15 Results