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2016
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.Puram, RV, Kowalczyk MS, de Boer CG, Schneider RK, Miller PG, McConkey M., Tothova Z., Tejero H., Heckl D., Järås M., Chen MC, Li H., Tamayo A., Cowley GS, Rozenblatt-Rosen O., Al-Shahrour F., Regev A., and Ebert BL Cell, 2016/04/07, Volume 165, Issue 2, p.303-16, (2016) Read More / View Supplemental Materials
Abstract
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.Doench, JG, Fusi N., Sullender M., Hegde M., Vaimberg EW, Donovan KF, Smith I., Tothova Z., Wilen C., Orchard R., Virgin HW, Listgarten J., and Root DE Nature biotechnology, 2016/01/18, (2016) Read More / View Supplemental Materials
Abstract
2014
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.Doench, JG, Hartenian E., Graham DB, Tothova Z., Hegde M., Smith I., Sullender M., Ebert BL, Xavier RJ, and Root DE Nature biotechnology, 2014/09/03, (2014) Read More / View Supplemental Materials
Abstract
2013
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.Hartwell, KA, Miller PG, Mukherjee S., Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M., Järås M., Puram R., Dancik V., Al-Shahrour F., Kindler T., Tothova Z., Chattopadhyay S., Hasaka T., Narayan R., Dai M., Huang C., Shterental S., et al. Nature chemical biology, 2013/12/01, Volume 9, Issue 12, p.840-8, (2013) Read More / View Supplemental Materials
Abstract
  • Showing 1-4 of 4 Results