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2013
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.Schroeder, FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J., Zhao WN, Reis S., Barker DD, Berry-Scott E., Kim SW, Clore EL, Hooker JM, Holson EB, Haggarty SJ, and Petryshen TL PloS one, 2013/01/01, Volume 8, Issue 8, p.e71323, (2013) Read More / View Supplemental Materials
Abstract
2012
Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.Fass, DM, Reis SA, Ghosh B., Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W., Barker DD, Mazitschek R., Schreiber SL, Tsai LH, and Haggarty SJ Neuropharmacology, 2012/07/04, (2012) Read More / View Supplemental Materials
Abstract
2010
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Marcaurelle, LA, Comer E., Dandapani S., Duvall JR, Gerard B., Kesavan S., Lee MD 4th, Liu H., Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A., Ryba TD, Suh BC, Wei J., Young DW, Akella LB, Ross NT, Zhang YL, et al. Journal of the American Chemical Society, 2010/12/01, Volume 132, Issue 47, p.16962-76, (2010) Read More / View Supplemental Materials
Abstract
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.Fass, DM, Shah R., Ghosh B., Hennig K., Norton S., Zhao WN, Reis SA, Klein PS, Mazitschek R., Maglathlin RL, Lewis TA, and Haggarty SJ ACS medicinal chemistry letters, 2010/10/08, Volume 2, Issue 1, p.39-42, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-4 of 4 Results