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2014
An Unbiased Approach To Identify Endogenous Substrates of "Histone" Deacetylase 8.Olson, DE, Udeshi ND, Wolfson NA, Pitcairn CA, Sullivan ED, Jaffe JD, Svinkina T., Natoli T., Lu X., Paulk J., McCarren P., Wagner FF, Barker D., Howe E., Lazzaro F., Gale JP, Zhang YL, Subramanian A., Fierke CA, Carr SA, et al. ACS chemical biology, 2014/08/11, (2014) Read More / View Supplemental Materials
Abstract
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.Lassen, KG, Kuballa P., Conway KL, Patel KK, Becker CE, Peloquin JM, Villablanca EJ, Norman JM, Liu TC, Heath RJ, Becker ML, Fagbami L., Horn H., Mercer J., Yilmaz OH, Jaffe JD, Shamji AF, Bhan AK, Carr SA, Daly M. J., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/05/12, (2014) Read More / View Supplemental Materials
Abstract
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.Lane, AA, Chapuy B., Lin CY, Tivey T., Li H., Townsend EC, van Bodegom D., Day TA, Wu SC, Liu H., Yoda A., Alexe G., Schinzel AC, Sullivan TJ, Malinge S., Taylor JE, Stegmaier K., Jaffe JD, Bustin M., Te Kronnie G., et al. Nature genetics, 2014/04/20, (2014) Read More / View Supplemental Materials
Abstract
2013
Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.Jaffe, JD, Wang Y., Chan HM, Zhang J., Huether R., Kryukov GV, Bhang HE, Taylor JE, Hu M., Englund NP, Yan F., Wang Z., Robert McDonald E 3rd, Wei L., Ma J., Easton J., Yu Z., Debeaumount R., Gibaja V., Venkatesan K., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1386-91, (2013) Read More / View Supplemental Materials
Abstract
Integrated proteomic analysis of post-translational modifications by serial enrichment.Mertins, P., Qiao JW, Patel J., Udeshi ND, Clauser KR, Mani D. R., Burgess MW, Gillette MA, Jaffe JD, and Carr SA Nature methods, 2013/07/01, Volume 10, Issue 7, p.634-7, (2013) Read More / View Supplemental Materials
Abstract
2012
H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions.Ku, M., Jaffe JD, Koche RP, Rheinbay E., Endoh M., Koseki H., Carr SA, and Bernstein BE Genome biology, 2012/10/03, Volume 13, Issue 10, p.R85, (2012) Read More / View Supplemental Materials
Abstract
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.Greulich, H., Kaplan B., Mertins P., Chen TH, Tanaka KE, Yun CH, Zhang X., Lee SH, Cho J., Ambrogio L., Liao R., Imielinski M., Banerji S., Berger AH, Lawrence MS, Zhang J., Pho NH, Walker SR, Winckler W., Getz G., et al. Proceedings of the National Academy of Sciences of the United States of America, 2012/09/04, Volume 109, Issue 36, p.14476-81, (2012) Read More / View Supplemental Materials
Abstract
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.Abdel-Wahab, O., Adli M., LaFave LM, Gao J., Hricik T., Shih AH, Pandey S., Patel JP, Chung YR, Koche R., Perna F., Zhao X., Taylor JE, Park CY, Carroll M., Melnick A., Nimer SD, Jaffe JD, Aifantis I., Bernstein BE, et al. Cancer cell, 2012/08/14, Volume 22, Issue 2, p.180-93, (2012) Read More / View Supplemental Materials
Abstract
Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.Udeshi, ND, Mani D. R., Eisenhaure T., Mertins P., Jaffe JD, Clauser KR, Hacohen N., and Carr SA Molecular & cellular proteomics : MCP, 2012/04/14, (2012) Read More / View Supplemental Materials
Abstract
Quantitative assessment of ChIP-grade antibodies directed against histone modifications reveals patterns of co-occurring marks on histone protein molecules.Peach, SE, Rudomin EL, Udeshi ND, Carr SA, and Jaffe JD Molecular & cellular proteomics : MCP, 2012/03/23, (2012) Read More / View Supplemental Materials
Abstract
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability.Luo, T., Masson K., Jaffe JD, Silkworth W., Ross NT, Scherer CA, Scholl C., Fröhling S., Carr SA, Stern AM, Schreiber SL, and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.2860-5, (2012) Read More / View Supplemental Materials
Abstract
iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics.Mertins, P., Udeshi ND, Clauser KR, Mani D. R., Patel J., Ong SE, Jaffe JD, and Carr SA Molecular & cellular proteomics : MCP, 2011/12/30, (2012) Read More / View Supplemental Materials
Abstract
2011
Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation.Tucker, EJ, Hershman SG, Köhrer C., Belcher-Timme CA, Patel J., Goldberger OA, Christodoulou J., Silberstein JM, McKenzie M., Ryan MT, Compton AG, Jaffe JD, Carr SA, Calvo SE, RajBhandary UL, Thorburn DR, and Mootha VK Cell metabolism, 2011/09/07, Volume 14, Issue 3, p.428-34, (2011) Read More / View Supplemental Materials
Abstract
The genome of the green anole lizard and a comparative analysis with birds and mammals.Alföldi, J., Di Palma F., Grabherr M., Williams C., Kong L., Mauceli E., Russell P., Lowe CB, Glor RE, Jaffe JD, Ray DA, Boissinot S., Shedlock AM, Botka C., Castoe TA, Colbourne JK, Fujita MK, Moreno RG, ten Hallers BF, Haussler D., et al. Nature, 2011/08/31, Volume 477, Issue 7366, p.587-91, (2011) Read More / View Supplemental Materials
Abstract
2010
Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry.Tabb, DL, Vega-Montoto L., Rudnick PA, Variyath AM, Ham AJ, Bunk DM, Kilpatrick LE, Billheimer DD, Blackman RK, Cardasis HL, Carr SA, Clauser KR, Jaffe JD, Kowalski KA, Neubert TA, Regnier FE, Schilling B., Tegeler TJ, Wang M., Wang P., et al. Journal of proteome research, 2010/02/05, Volume 9, Issue 2, p.761-76, (2010) Read More / View Supplemental Materials
Abstract
Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses.Rudnick, PA, Clauser KR, Kilpatrick LE, Tchekhovskoi DV, Neta P., Blonder N., Billheimer DD, Blackman RK, Bunk DM, Cardasis HL, Ham AJ, Jaffe JD, Kinsinger CR, Mesri M., Neubert TA, Schilling B., Tabb DL, Tegeler TJ, Vega-Montoto L., Variyath AM, et al. Molecular & cellular proteomics : MCP, 2010/02/01, Volume 9, Issue 2, p.225-41, (2010) Read More / View Supplemental Materials
Abstract
2009
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.Markljung, E., Jiang L., Jaffe JD, Mikkelsen TS, Wallerman O., Larhammar M., Zhang X., Wang L., Saenz-Vash V., Gnirke A., Lindroth AM, Barrés R., Yan J., Strömberg S., De S., Pontén F., Lander E. S., Carr SA, Zierath JR, Kullander K., et al. PLoS biology, 2009/12/01, Volume 7, Issue 12, p.e1000256, (2009) Read More / View Supplemental Materials
Abstract
Directed sample interrogation utilizing an accurate mass exclusion-based data-dependent acquisition strategy (AMEx).Rudomin, EL, Carr SA, and Jaffe JD Journal of proteome research, 2009/06/01, Volume 8, Issue 6, p.3154-60, (2009) Read More / View Supplemental Materials
Abstract
2008
Accurate inclusion mass screening: a bridge from unbiased discovery to targeted assay development for biomarker verification.Jaffe, JD, Keshishian H., Chang B., Addona TA, Gillette MA, and Carr SA Molecular & cellular proteomics : MCP, 2008/10/01, Volume 7, Issue 10, p.1952-62, (2008) Read More / View Supplemental Materials
Abstract
2006
PEPPeR, a platform for experimental proteomic pattern recognition.Jaffe, JD, Mani D. R., Leptos KC, Church GM, Gillette MA, and Carr SA Molecular & cellular proteomics : MCP, 2006/10/01, Volume 5, Issue 10, p.1927-41, (2006) Read More / View Supplemental Materials
Abstract
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.Frias, MA, Thoreen CC, Jaffe JD, Schroder W., Sculley T., Carr SA, and Sabatini DM Current biology : CB, 2006/09/19, Volume 16, Issue 18, p.1865-70, (2006) Read More / View Supplemental Materials
Abstract
  • Showing 1-21 of 21 Results