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2013
A Small-Molecule Inducer of PDX1 Expression Identified by High-Throughput Screening.Yuan, Y., Hartland K., Boskovic Z., Wang Y., Walpita D., Lysy PA, Zhong C., Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, and Wagner BK Chemistry & biology, 2013/11/23, (2013) Read More / View Supplemental Materials
Abstract
Selective access to trisubstituted macrocyclic e- and z-alkenes from the ring-closing metathesis of vinylsiloxanes.Wang, Y., Jimenez M., Sheehan P., Zhong C., Hung AW, Tam CP, and Young DW Organic letters, 2013/03/15, Volume 15, Issue 6, p.1218-21, (2013) Read More / View Supplemental Materials
Abstract
2011
Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts.Zhong, C., Wang Y., Hung AW, Schreiber SL, and Young DW Organic letters, 2011/10/21, Volume 13, Issue 20, p.5556-9, (2011) Read More / View Supplemental Materials
Abstract
Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions.Pandya, BA, Dandapani S., Duvall JR, Rowley A., Mulrooney CA, Ryba T., Dombrowski M., Harton M., Young DW, and Marcaurelle LA Tetrahedron, 2011/08/26, Volume 67, Issue 34, p.6131-6137, (2011) Read More / View Supplemental Materials
Abstract
Control of olefin geometry in macrocyclic ring-closing metathesis using a removable silyl group.Wang, Y., Jimenez M., Hansen AS, Raiber EA, Schreiber SL, and Young DW Journal of the American Chemical Society, 2011/06/22, Volume 133, Issue 24, p.9196-9, (2011) Read More / View Supplemental Materials
Abstract
Route to three-dimensional fragments using diversity-oriented synthesis.Hung, AW, Ramek A., Wang Y., Kaya T., Wilson JA, Clemons PA, and Young DW Proceedings of the National Academy of Sciences of the United States of America, 2011/04/26, Volume 108, Issue 17, p.6799-804, (2011) Read More / View Supplemental Materials
Abstract
2010
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Marcaurelle, LA, Comer E., Dandapani S., Duvall JR, Gerard B., Kesavan S., Lee MD 4th, Liu H., Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A., Ryba TD, Suh BC, Wei J., Young DW, Akella LB, Ross NT, Zhang YL, et al. Journal of the American Chemical Society, 2010/12/01, Volume 132, Issue 47, p.16962-76, (2010) Read More / View Supplemental Materials
Abstract
Distinct biological network properties between the targets of natural products and disease genes.Dancík, V., Seiler KP, Young DW, Schreiber SL, and Clemons PA Journal of the American Chemical Society, 2010/07/14, Volume 132, Issue 27, p.9259-61, (2010) Read More / View Supplemental Materials
Abstract
Synthetic chemistry: An upfront investment.Young, DW Nature chemical biology, 2010/03/01, Volume 6, Issue 3, p.174-175, (2010) Read More / View Supplemental Materials
2009
Accessing skeletal diversity using catalyst control: formation of n and n + 1 macrocyclic triazole rings.Kelly, AR, Wei J., Kesavan S., Marié JC, Windmon N., Young DW, and Marcaurelle LA Organic letters, 2009/06/04, Volume 11, Issue 11, p.2257-60, (2009) Read More / View Supplemental Materials
Abstract
  • Showing 1-10 of 10 Results