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  • Showing 1-9 of 9 Results
2014
Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.Pugh, TJ, Yu W., Yang J., Field AL, Ambrogio L., Carter SL, Cibulskis K., Giannikopoulos P., Kiezun A., Kim J., McKenna A., Nickerson E., Getz G., Hoffher S., Messinger YH, Dehner LP, Roberts CW, Rodriguez-Galindo C., Williams GM, Rossi CT, et al. Oncogene, 2014/06/09, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.Van Allen, EM, Wagle N., Stojanov P., Perrin DL, Cibulskis K., Marlow S., Jane-Valbuena J., Friedrich DC, Kryukov G., Carter SL, McKenna A., Sivachenko A., Rosenberg M., Kiezun A., Voet D., Lawrence M., Lichtenstein LT, Gentry JG, Huang FW, Fostel J., et al. Nature medicine, 2014/06/01, Volume 20, Issue 6, p.682-8, (2014) Read More / View Supplemental Materials
Abstract
2013
Somatic mutation of CDKN1B in small intestine neuroendocrine tumors.Francis, JM, Kiezun A., Ramos AH, Serra S., Pedamallu CS, Qian ZR, Banck MS, Kanwar R., Kulkarni AA, Karpathakis A., Manzo V., Contractor T., Philips J., Nickerson E., Pho N., Hooshmand SM, Brais LK, Lawrence MS, Pugh T., McKenna A., et al. Nature genetics, 2013/12/01, Volume 45, Issue 12, p.1483-6, (2013) Read More / View Supplemental Materials
Abstract
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.Roberts, SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D., Stojanov P., Kiezun A., Kryukov GV, Carter SL, Saksena G., Harris S., Shah RR, Resnick MA, Getz G., and Gordenin DA Nature genetics, 2013/08/28, Volume 45, Issue 9, p.970-6, (2013) Read More / View Supplemental Materials
Abstract
Mutational heterogeneity in cancer and the search for new cancer-associated genes.Lawrence, MS, Stojanov P., Polak P., Kryukov GV, Cibulskis K., Sivachenko A., Carter SL, Stewart C., Mermel CH, Roberts SA, Kiezun A., Hammerman PS, McKenna A., Drier Y., Zou L., Ramos AH, Pugh TJ, Stransky N., Helman E., Kim J., et al. Nature, 2013/07/11, Volume 499, Issue 7457, p.214-8, (2013) Read More / View Supplemental Materials
Abstract
Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency.Kiezun, A., Pulit SL, Francioli LC, van Dijk F., Swertz M., Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C., Genome of the Netherlands Consortium, de Bakker PI, and Sunyaev SR PLoS genetics, 2013/02/01, Volume 9, Issue 2, p.e1003301, (2013) Read More / View Supplemental Materials
Abstract
The genetic landscape of high-risk neuroblastoma.Pugh, TJ, Morozova O., Attiyeh EF, Asgharzadeh S., Wei JS, Auclair D., Carter SL, Cibulskis K., Hanna M., Kiezun A., Kim J., Lawrence MS, McKenna A., Pedamallu CS, Ramos AH, Shefler E., Sivachenko A., Sougnez C., Stewart C., Ally A., et al. Nature genetics, 2013/01/20, (2013) Read More / View Supplemental Materials
Abstract
2012
Exome sequencing and the genetic basis of complex traits.Kiezun, A., Garimella K., Do R., Stitziel NO, Neale BM, McLaren PJ, Gupta N., Sklar P., Sullivan PF, Moran JL, Hultman CM, Lichtenstein P., Magnusson P., Lehner T., Shugart YY, Price AL, de Bakker PI, Purcell SM, and Sunyaev SR Nature genetics, 2012/05/29, Volume 44, Issue 6, p.623-30, (2012) Read More / View Supplemental Materials
2011
Computational and statistical approaches to analyzing variants identified by exome sequencing.Stitziel, NO, Kiezun A., and Sunyaev S. Genome biology, 2011/09/14, Volume 12, Issue 9, p.227, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-9 of 9 Results