Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.Scully, SS, Tang AJ, Lundh M., Mosher CM, Perkins KM, and Wagner BK Journal of medicinal chemistry, 2013/05/13, (2013)
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Abstract
Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.Okada, Y., and Plenge RM Arthritis and rheumatism, 2013/05/10, (2013)
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Targeted exome sequencing of suspected mitochondrial disorders.Lieber, DS, Calvo SE, Shanahan K., Slate NG, Liu S., Hershman SG, Gold NB, Chapman BA, Thorburn DR, Berry GT, Schmahmann JD, Borowsky ML, Mueller DM, Sims KB, and Mootha VK Neurology, 2013/05/07, Volume 80, Issue 19, p.1762-1770, (2013)
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Abstract
miR-155 in Acute Myeloid Leukemia: Not Merely a Prognostic Marker?Joyce, CE, and Novina CD Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/05/06, (2013)
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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.Lamming, DW, Ye L., Astle MC, Baur JA, Sabatini DM, and Harrison DE Aging cell, 2013/05/04, (2013)
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Abstract
Arboretum: Reconstruction and analysis of the evolutionary history of condition-specific transcriptional modules.Roy, S., Wapinski I., Pfiffner J., French C., Socha A., Konieczka J., Habib N., Kellis M., Thompson D., and Regev A. Genome research, 2013/05/02, (2013)
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Abstract
Integrated genomic characterization of endometrial carcinoma.Cancer Genome Atlas Research, Network, Genome sequencing centres: Broad Institute, Getz G., Gabriel SB, Cibulskis K., Lander E., Sivachenko A., Sougnez C., Lawrence M., Washington University in St Louis, Kandoth C., Dooling D., Fulton R., Fulton L., Kalicki-Veizer J., McLellan MD, O'Laughlin M., Schmidt H., Wilson RK, Ye K., et al. Nature, 2013/05/02, Volume 497, Issue 7447, p.67-73, (2013)
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Abstract
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia.The Cancer Genome Atlas Research, Network The New England journal of medicine, 2013/05/01, (2013)
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Abstract
High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma.Crompton, BD, Carlton AL, Thorner AR, Christie AL, Du J., Calicchio ML, Rivera MN, Fleming MD, Kohl NE, Kung AL, and Stegmaier K. Cancer research, 2013/05/01, Volume 73, Issue 9, p.2873-83, (2013)
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Abstract
Improved ancestry inference using weights from external reference panels.Chen, CY, Pollack S., Hunter DJ, Hirschhorn JN, Kraft P., and Price AL Bioinformatics (Oxford, England), 2013/04/30, (2013)
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Abstract
From genetics of inflammatory bowel disease towards mechanistic insights.Graham, DB, and Xavier RJ Trends in immunology, 2013/04/29, (2013)
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Abstract
Immunological Genome Project and systems immunology.Shay, T., and Kang J. Trends in immunology, 2013/04/27, (2013)
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Abstract
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.Plenge, RM, Greenberg JD, Mangravite LM, Derry JM, Stahl EA, Coenen MJ, Barton A., Padyukov L., Klareskog L., Gregersen PK, Mariette X., Moreland LW, Bridges SL Jr, de Vries N., Huizinga TW, Guchelaar HJ, International Rheumatoid Arthritis Consortium(INTERACT), Friend SH, and Stolovitzky G. Nature genetics, 2013/04/26, Volume 45, Issue 5, p.468-9, (2013)
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Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.Dulak, AM, Stojanov P., Peng S., Lawrence MS, Fox C., Stewart C., Bandla S., Imamura Y., Schumacher SE, Shefler E., McKenna A., Carter SL, Cibulskis K., Sivachenko A., Saksena G., Voet D., Ramos AH, Auclair D., Thompson K., Sougnez C., et al. Nature genetics, 2013/04/26, Volume 45, Issue 5, p.478-86, (2013)
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Abstract
Genomics of Loa loa, a Wolbachia-free filarial parasite of humans.Desjardins, CA, Cerqueira GC, Goldberg JM, Dunning Hotopp JC, Haas BJ, Zucker J., Ribeiro JM, Saif S., Levin JZ, Fan L., Zeng Q., Russ C., Wortman JR, Fink DL, Birren BW, and Nutman TB Nature genetics, 2013/04/26, Volume 45, Issue 5, p.495-500, (2013)
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Abstract
Punctuated evolution of prostate cancer genomes.Baca, SC, Prandi D., Lawrence MS, Mosquera JM, Romanel A., Drier Y., Park K., Kitabayashi N., MacDonald TY, Ghandi M., Van Allen E., Kryukov GV, Sboner A., Theurillat JP, Soong TD, Nickerson E., Auclair D., Tewari A., Beltran H., Onofrio RC, et al. Cell, 2013/04/25, Volume 153, Issue 3, p.666-77, (2013)
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Abstract
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.Hett, EC, Slater LH, Mark KG, Kawate T., Monks BG, Stutz A., Latz E., and Hung DT Nature chemical biology, 2013/04/21, (2013)
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Abstract
DEVELOPMENTAL TIMING OF CHILD MALTREATMENT AND SYMPTOMS OF DEPRESSION AND SUICIDAL IDEATION IN YOUNG ADULTHOOD: RESULTS FROM THE NATIONAL LONGITUDINAL STUDY OF ADOLESCENT HEALTH.Dunn, EC, McLaughlin KA, Slopen N., Rosand J., and Smoller JW Depression and anxiety, 2013/04/16, (2013)
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Abstract
DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1.Soda, T., Frank C., Ishizuka K., Baccarella A., Park YU, Flood Z., Park SK, Sawa A., and Tsai LH Molecular psychiatry, 2013/04/16, (2013)
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Abstract
Clinical Analysis and Interpretation of Cancer Genome Data.Van Allen, EM, Wagle N., and Levy MA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/04/15, (2013)
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Abstract
Genomics-Driven Oncology: Framework for an Emerging Paradigm.Garraway, LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/04/15, (2013)
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Abstract
Precision Oncology: An Overview.Garraway, LA, Verwey J., and Ballman K. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/04/15, (2013)
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An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.Mulrooney, CA, Lahr DL, Quintin MJ, Youngsaye W., Moccia D., Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P., Bittker JA, Clemons PA, Brudz S., Dandapani S., Duvall JR, Tolliday NJ, and De Souza A. Journal of computer-aided molecular design, 2013/04/13, (2013)
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Abstract
Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response.Grant, SS, and Hung DT Virulence, 2013/04/05, Volume 4, Issue 4, (2013)
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Abstract
Common risk alleles for inflammatory diseases are targets of recent positive selection.Raj, T., Kuchroo M., Replogle JM, Raychaudhuri S., Stranger BE, and De Jager PL American journal of human genetics, 2013/04/04, Volume 92, Issue 4, p.517-29, (2013)
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Abstract
Antidepressant response and polygenes.Purcell, SM Biological psychiatry, 2013/04/01, Volume 73, Issue 7, p.600-1, (2013)
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Commentary: Can maternal-paternal comparisons contribute to our understanding of maternal pre-pregnancy obesity and its association with offspring cognitive outcomes?Brion, MJ International journal of epidemiology, 2013/04/01, Volume 42, Issue 2, p.518-9, (2013)
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Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli.Gat-Viks, I., Chevrier N., Wilentzik R., Eisenhaure T., Raychowdhury R., Steuerman Y., Shalek AK, Hacohen N., Amit I., and Regev A. Nature biotechnology, 2013/04/01, Volume 31, Issue 4, p.342-9, (2013)
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Abstract
Response to sul and eskin.Price, AL, Zaitlen NA, Reich D., and Patterson N. Nature reviews. Genetics, 2013/04/01, Volume 14, Issue 4, p.300, (2013)
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Target identification and mechanism of action in chemical biology and drug discovery.Schenone, M., Dančík V., Wagner BK, and Clemons PA Nature chemical biology, 2013/04/01, Volume 9, Issue 4, p.232-40, (2013)
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Abstract
IKKε-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex.Zhou, AY, Shen RR, Kim E., Lock YJ, Xu M., Chen ZJ, and Hahn WC Cell reports, 2013/03/28, Volume 3, Issue 3, p.724-33, (2013)
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Abstract
Lessons from the cancer genome.Garraway, LA, and Lander E. S. Cell, 2013/03/28, Volume 153, Issue 1, p.17-37, (2013)
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Abstract
Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1.Tu, D., Zhu Z., Zhou AY, Yun CH, Lee KE, Toms AV, Li Y., Dunn GP, Chan E., Thai T., Yang S., Ficarro SB, Marto JA, Jeon H., Hahn WC, Barbie DA, and Eck MJ Cell reports, 2013/03/28, Volume 3, Issue 3, p.747-58, (2013)
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Abstract
Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death.Adams, DJ, Boskovic ZV, Theriault JR, Wang AJ, Stern AM, Wagner BK, Shamji AF, and Schreiber SL ACS chemical biology, 2013/03/25, (2013)
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Abstract
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.Germain, AR, Carmody LC, Nag PP, Morgan B., VerPlank L., Fernandez C., Donckele E., Feng Y., Perez JR, Dandapani S., Palmer M., Lander E. S., Gupta PB, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2013/03/15, Volume 23, Issue 6, p.1834-8, (2013)
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Abstract
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging.Rhee, HW, Zou P., Udeshi ND, Martell JD, Mootha VK, Carr SA, and Ting AY Science (New York, N.Y.), 2013/03/15, Volume 339, Issue 6125, p.1328-31, (2013)
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Abstract
Selective access to trisubstituted macrocyclic e- and z-alkenes from the ring-closing metathesis of vinylsiloxanes.Wang, Y., Jimenez M., Sheehan P., Zhong C., Hung AW, Tam CP, and Young DW Organic letters, 2013/03/15, Volume 15, Issue 6, p.1218-21, (2013)
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Abstract
Estimating selection on synonymous codon usage from noisy experimental data.Wallace, EW, Airoldi EM, and Drummond DA Molecular biology and evolution, 2013/03/14, (2013)
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Abstract
Nozzle: a report generation toolkit for data analysis pipelines.Gehlenborg, N., Noble MS, Getz G., Chin L., and Park PJ Bioinformatics (Oxford, England), 2013/03/11, (2013)
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Abstract
Genome-wide association studies of hematologic phenotypes: a window into human hematopoiesis.Sankaran, VG, and Orkin SH Current opinion in genetics & development, 2013/03/07, (2013)
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Abstract
An Inflammatory Situation: SOX2 and STAT3 Cooperate in Squamous Cell Carcinoma Initiation.Bass, AJ, and Wang TC Cell stem cell, 2013/03/07, Volume 12, Issue 3, p.266-8, (2013)
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Abstract
Dynamic regulatory network controlling TH17 cell differentiation.Yosef, N., Shalek AK, Gaublomme JT, Jin H., Lee Y., Awasthi A., Wu C., Karwacz K., Xiao S., Jorgolli M., Gennert D., Satija R., Shakya A., Lu DY, Trombetta JJ, Pillai MR, Ratcliffe PJ, Coleman ML, Bix M., Tantin D., et al. Nature, 2013/03/06, (2013)
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Abstract
Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1.Wu, C., Yosef N., Thalhamer T., Zhu C., Xiao S., Kishi Y., Regev A., and Kuchroo VK Nature, 2013/03/06, (2013)
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Abstract
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.Kleinewietfeld, M., Manzel A., Titze J., Kvakan H., Yosef N., Linker RA, Muller DN, and Hafler DA Nature, 2013/03/06, (2013)
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Abstract
Effector-triggered versus pattern-triggered immunity: how animals sense pathogens.Stuart, LM, Paquette N., and Boyer L. Nature reviews. Immunology, 2013/03/01, Volume 13, Issue 3, p.199-206, (2013)
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Abstract
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.Kirby, A., Gnirke A., Jaffe DB, Barešová V., Pochet N., Blumenstiel B., Ye C., Aird D., Stevens C., Robinson JT, Cabili MN, Gat-Viks I., Kelliher E., Daza R., DeFelice M., Hůlková H., Sovová J., Vylet'al P., Antignac C., Guttman M., et al. Nature genetics, 2013/03/01, Volume 45, Issue 3, p.299-303, (2013)
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Abstract
Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition.Puissant, A., Frumm SM, Alexe G., Bassil CF, Qi J., Chanthery YH, Nekritz EA, Zeid R., Gustafson WC, Greninger P., Garnett MJ, McDermott U., Benes CH, Kung AL, Weiss WA, Bradner JE, and Stegmaier K. Cancer discovery, 2013/03/01, Volume 3, Issue 3, p.308-323, (2013)
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Abstract
Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain.Kokel, D., Dunn TW, Ahrens MB, Alshut R., Cheung CY, Saint-Amant L., Bruni G., Mateus R., van Ham TJ, Shiraki T., Fukada Y., Kojima D., Yeh JR, Mikut R., von Lintig J., Engert F., and Peterson RT The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013/02/27, Volume 33, Issue 9, p.3834-3843, (2013)
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Abstract
Using population admixture to help complete maps of the human genome.Genovese, G., Handsaker RE, Li H., Altemose N., Lindgren AM, Chambert K., Pasaniuc B., Price AL, Reich D., Morton CC, Pollak MR, Wilson JG, and McCarroll SA Nature genetics, 2013/02/24, (2013)
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Abstract
Conservation and divergence in the transcriptional programs of the human and mouse immune systems.Shay, T., Jojic V., Zuk O., Rothamel K., Puyraimond-Zemmour D., Feng T., Wakamatsu E., Benoist C., Koller D., Regev A., and ImmGen Consortium Proceedings of the National Academy of Sciences of the United States of America, 2013/02/19, Volume 110, Issue 8, p.2946-51, (2013)
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Abstract
Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.de Miguel-Yanes, JM, Porneala B., Pencina MJ, Fox CS, Florez JC, Siscovick DS, Dupuis J., and Meigs JB Journal of hypertension, 2013/02/19, (2013)
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Abstract
Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif.Wagner, FF, Olson DE, Gale JP, Kaya T., Weïwer M., Aidoud N., Thomas M., Davoine EL, Lemercier BC, Zhang YL, and Holson EB Journal of medicinal chemistry, 2013/02/18, (2013)
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Abstract
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.Landau, DA, Carter SL, Stojanov P., McKenna A., Stevenson K., Lawrence MS, Sougnez C., Stewart C., Sivachenko A., Wang L., Wan Y., Zhang W., Shukla SA, Vartanov A., Fernandes SM, Saksena G., Cibulskis K., Tesar B., Gabriel S., Hacohen N., et al. Cell, 2013/02/14, Volume 152, Issue 4, p.714-26, (2013)
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Abstract
Identifying recent adaptations in large-scale genomic data.Grossman, SR, Andersen KG, Shlyakhter I., Tabrizi S., Winnicki S., Yen A., Park DJ, Griesemer D., Karlsson EK, Wong SH, Cabili M., Adegbola RA, Bamezai RN, Hill AV, Vannberg FO, Rinn JL, 1000 Genomes Project, Lander E. S., Schaffner SF, and Sabeti PC Cell, 2013/02/14, Volume 152, Issue 4, p.703-13, (2013)
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Abstract
Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant.Kamberov, YG, Wang S., Tan J., Gerbault P., Wark A., Tan L., Yang Y., Li S., Tang K., Chen H., Powell A., Itan Y., Fuller D., Lohmueller J., Mao J., Schachar A., Paymer M., Hostetter E., Byrne E., Burnett M., et al. Cell, 2013/02/14, Volume 152, Issue 4, p.691-702, (2013)
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Abstract
APOL1 variants and kidney disease in people of recent African ancestry.Genovese, G., Friedman DJ, and Pollak MR Nature reviews. Nephrology, 2013/02/12, Volume 9, Issue 4, p.240-4, (2013)
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Abstract
DNA methylation: roles in mammalian development.Smith, ZD, and Meissner A. Nature reviews. Genetics, 2013/02/12, Volume 14, Issue 3, p.204-20, (2013)
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Abstract
Photochemical activation of TRPA1 channels in neurons and animals.Kokel, D., Cheung CY, Mills R., Coutinho-Budd J., Huang L., Setola V., Sprague J., Jin S., Jin YN, Huang XP, Bruni G., Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, and Peterson RT Nature chemical biology, 2013/02/10, (2013)
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Abstract
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples.Cibulskis, K., Lawrence MS, Carter SL, Sivachenko A., Jaffe D., Sougnez C., Gabriel S., Meyerson M., Lander E. S., and Getz G. Nature biotechnology, 2013/02/10, (2013)
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Abstract
The simplest explanation: passive DNA demethylation in PGCs.Smith, ZD, and Meissner A. The EMBO journal, 2013/02/06, Volume 32, Issue 3, p.318-21, (2013)
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Chromatin marks identify critical cell types for fine mapping complex trait variants.Trynka, G., Sandor C., Han B., Xu H., Stranger BE, Liu XS, and Raychaudhuri S. Nature genetics, 2013/02/01, Volume 45, Issue 2, p.124-30, (2013)
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Abstract
Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency.Kiezun, A., Pulit SL, Francioli LC, van Dijk F., Swertz M., Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C., Genome of the Netherlands Consortium, de Bakker PI, and Sunyaev SR PLoS genetics, 2013/02/01, Volume 9, Issue 2, p.e1003301, (2013)
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Abstract
Fine-scale mapping of the nasonia genome to chromosomes using a high-density genotyping microarray.Desjardins, CA, Gadau J., Lopez JA, Niehuis O., Avery AR, Loehlin DW, Richards S., Colbourne JK, and Werren JH G3 (Bethesda, Md.), 2013/02/01, Volume 3, Issue 2, p.205-15, (2013)
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Abstract
Histone acetylation: molecular mnemonics on the chromatin.Gräff, J., and Tsai LH Nature reviews. Neuroscience, 2013/02/01, Volume 14, Issue 2, p.97-111, (2013)
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Abstract
Large-scale metagenomic sequence clustering on map-reduce clusters.Yang, X., Zola J., and Aluru S. Journal of bioinformatics and computational biology, 2013/02/01, Volume 11, Issue 1, p.1340001, (2013)
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Abstract
Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors.Chmielecki, J., Crago AM, Rosenberg M., O'Connor R., Walker SR, Ambrogio L., Auclair D., McKenna A., Heinrich MC, Frank DA, and Meyerson M. Nature genetics, 2013/02/01, Volume 45, Issue 2, p.131-2, (2013)
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Abstract
Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues.Zhu, J., Adli M., Zou JY, Verstappen G., Coyne M., Zhang X., Durham T., Miri M., Deshpande V., De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R., Cowan CA, Meissner A., Epstein CB, Shoresh N., and Bernstein BE Cell, 2013/01/31, Volume 152, Issue 3, p.642-54, (2013)
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Abstract
Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci.Li, Q., Seo JH, Stranger B., McKenna A., Pe'er I., LaFramboise T., Brown M., Tyekucheva S., and Freedman ML Cell, 2013/01/31, Volume 152, Issue 3, p.633-41, (2013)
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Abstract
Epigenetic mechanisms in mood disorders: Targeting neuroplasticity.Fass, DM, Schroeder FA, Perlis RH, and Haggarty SJ Neuroscience, 2013/01/30, (2013)
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Abstract
Eukaryotic virulence determinants utilize phosphoinositides at the ER and host cell surface.Jiang, RH, Stahelin RV, Bhattacharjee S., and Haldar K. Trends in microbiology, 2013/01/29, (2013)
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Abstract
Human systems immunology: Hypothesis-based modeling and unbiased data-driven approaches.Arazi, A., Pendergraft WF 3rd, Ribeiro RM, Perelson AS, and Hacohen N. Seminars in immunology, 2013/01/29, (2013)
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Abstract
Highly Recurrent TERT Promoter Mutations in Human Melanoma.Huang, FW, Hodis E., Xu MJ, Kryukov GV, Chin L., and Garraway LA Science (New York, N.Y.), 2013/01/24, (2013)
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Abstract
Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.Lim, ET, Raychaudhuri S., Sanders SJ, Stevens C., Sabo A., Macarthur DG, Neale BM, Kirby A., Ruderfer DM, Fromer M., Lek M., Liu L., Flannick J., Ripke S., Nagaswamy U., Muzny D., Reid JG, Hawes A., Newsham I., Wu Y., et al. Neuron, 2013/01/23, Volume 77, Issue 2, p.235-42, (2013)
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Abstract
Using Whole-Exome Sequencing to Identify Inherited Causes of Autism.Yu, TW, Chahrour MH, Coulter ME, Jiralerspong S., Okamura-Ikeda K., Ataman B., Schmitz-Abe K., Harmin DA, Adli M., Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J., Nasir RH, Ware J., et al. Neuron, 2013/01/23, Volume 77, Issue 2, p.259-273, (2013)
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Abstract
Ultranet: efficient solver for the sparse inverse covariance selection problem in gene network modeling.Järvstråt, L., Johansson M., Gullberg U., and Nilsson B. Bioinformatics (Oxford, England), 2013/01/21, (2013)
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Abstract
The genetic landscape of high-risk neuroblastoma.Pugh, TJ, Morozova O., Attiyeh EF, Asgharzadeh S., Wei JS, Auclair D., Carter SL, Cibulskis K., Hanna M., Kiezun A., Kim J., Lawrence MS, Lichenstein L., McKenna A., Pedamallu CS, Ramos AH, Shefler E., Sivachenko A., Sougnez C., Stewart C., et al. Nature genetics, 2013/01/20, (2013)
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Abstract
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.Brastianos, PK, Horowitz PM, Santagata S., Jones RT, McKenna A., Getz G., Ligon KL, Palescandolo E., Van Hummelen P., Ducar MD, Raza A., Sunkavalli A., Macconaill LE, Stemmer-Rachamimov AO, Louis DN, Hahn WC, Dunn IF, and Beroukhim R. Nature genetics, 2013/01/20, (2013)
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Abstract
Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: IV. viral proteinase slides along DNA to locate and process its substrates.Blainey, PC, Graziano V., Pérez-Berná AJ, McGrath WJ, Flint SJ, San Martín C., Xie XS, and Mangel WF The Journal of biological chemistry, 2013/01/18, Volume 288, Issue 3, p.2092-102, (2013)
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Abstract
ATG5 regulates plasma cell differentiation.Conway, KL, Kuballa P., Khor B., Zhang M., Shi HN, Virgin HW, and Xavier RJ Autophagy, 2013/01/17, Volume 9, Issue 4, (2013)
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Abstract
Prognostic Gene-Expression Signature for Patients with Hepatitis C-Related Early-Stage Cirrhosis.Hoshida, Y., Villanueva A., Sangiovanni A., Sole M., Hur C., Andersson KL, Chung RT, Gould J., Kojima K., Gupta S., Taylor B., Crenshaw A., Gabriel S., Minguez B., Iavarone M., Friedman SL, Colombo M., Llovet JM, and Golub T. R. Gastroenterology, 2013/01/17, (2013)
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Abstract
Mosaic copy number variation in schizophrenia.Ruderfer, DM, Chambert K., Moran J., Talkowski M., Chen ES, Gigek C., Gusella JF, Blackwood DH, Corvin A., Gurling HM, Hultman CM, Kirov G., Magnusson P., O'Donovan MC, Owen MJ, Pato C., St Clair D., Sullivan PF, Purcell SM, Sklar P., et al. European journal of human genetics : EJHG, 2013/01/16, (2013)
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Abstract
Rare, Low-Frequency, and Common Variants in the Protein-Coding Sequence of Biological Candidate Genes from GWASs Contribute to Risk of Rheumatoid Arthritis.Diogo, D., Kurreeman F., Stahl EA, Liao KP, Gupta N., Greenberg JD, Rivas MA, Hickey B., Flannick J., Thomson B., Guiducci C., Ripke S., Adzhubey I., Barton A., Kremer JM, Alfredsson L., Consortium of Rheumatology Researchers of North America, Rheumatoid Arthritis Consortium International, Sunyaev S., Martin J., et al. American journal of human genetics, 2013/01/10, Volume 92, Issue 1, p.15-27, (2013)
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Abstract
Complementary RNA and Protein Profiling Identifies Iron as a Key Regulator of Mitochondrial Biogenesis.Rensvold, JW, Ong SE, Jeevananthan A., Carr SA, Mootha VK, and Pagliarini DJ Cell reports, 2013/01/09, (2013)
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Abstract
Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation.Costello, M., Pugh TJ, Fennell TJ, Stewart C., Lichtenstein L., Meldrim JC, Fostel JL, Friedrich DC, Perrin D., Dionne D., Kim S., Gabriel SB, Lander E. S., Fisher S., and Getz G. Nucleic acids research, 2013/01/08, (2013)
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Abstract
The future is now: single-cell genomics of bacteria and archaea.Blainey, PC FEMS microbiology reviews, 2013/01/08, (2013)
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Abstract
A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition.Whittaker, SR, Theurillat JP, Van Allen E., Wagle N., Hsiao J., Cowley GS, Schadendorf D., Root DE, and Garraway LA Cancer discovery, 2013/01/03, (2013)
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Abstract
Multiplex Genome Engineering Using CRISPR/Cas Systems.Cong, L., Ran FA, Cox D., Lin S., Barretto R., Habib N., Hsu PD, Wu X., Jiang W., Marraffini LA, and Zhang F. Science (New York, N.Y.), 2013/01/03, (2013)
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Abstract
Computational prediction of lysine acetylation proteome-wide.Basu, A. Methods in molecular biology (Clifton, N.J.), 2013/01/01, Volume 981, p.127-36, (2013)
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Abstract
Genetic Surveillance Detects Both Clonal and Epidemic Transmission of Malaria following Enhanced Intervention in Senegal.Daniels, R., Chang HH, Séne PD, Park DC, Neafsey DE, Schaffner SF, Hamilton EJ, Lukens AK, Van Tyne D., Mboup S., Sabeti PC, Ndiaye D., Wirth DF, Hartl DL, and Volkman SK PloS one, 2013/01/01, Volume 8, Issue 4, p.e60780, (2013)
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Abstract
MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling.Plovanich, M., Bogorad RL, Sancak Y., Kamer KJ, Strittmatter L., Li AA, Girgis HS, Kuchimanchi S., De Groot J., Speciner L., Taneja N., Oshea J., Koteliansky V., and Mootha VK PloS one, 2013/01/01, Volume 8, Issue 2, p.e55785, (2013)
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Abstract
Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry.Gillette, MA, and Carr SA Nature methods, 2013/01/01, Volume 10, Issue 1, p.28-34, (2013)
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Abstract
Reconstructing roma history from genome-wide data.Moorjani, P., Patterson N., Loh PR, Lipson M., Kisfali P., Melegh BI, Bonin M., Kádaši L., Rieß O., Berger B., Reich D., and Melegh B. PloS one, 2013/01/01, Volume 8, Issue 3, p.e58633, (2013)
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Abstract
‘Big data’ from shrinking pathogen populations.Neafsey, DE Molecular ecology, 2013/01/01, Volume 22, Issue 2, p.271-2, (2013)
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Abstract
