
Found 914 results
RNA-SeQC: RNA-seq metrics for quality control and process optimization. Bioinformatics (Oxford, England), 2012/06/01, Volume 28, Issue 11, p.1530-2, (2012)
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Abstract
Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells. Cancer research, 2012/05/01, Volume 72, Issue 9, p.2373-82, (2012)
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Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles. Bioorganic & medicinal chemistry letters, 2012/05/01, Volume 22, Issue 9, p.3362-5, (2012)
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Absolute quantification of somatic DNA alterations in human cancer. Nature biotechnology, 2012/04/29, (2012)
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Apolipoprotein E Genotype Predicts Hematoma Expansion in Lobar Intracerebral Hemorrhage. Stroke; a journal of cerebral circulation, 2012/04/24, (2012)
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Autophagy and the immune system. Annual review of immunology, 2012/04/23, Volume 30, p.611-46, (2012)
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Sex-specific influence of DRD2 on ADHD-type temperament in a large population-based birth cohort. Psychiatric genetics, 2012/04/23, (2012)
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Not lost in translation: stepwise regulation of microRNA targets. The EMBO journal, 2012/04/20, (2012)
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Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency. Cancer cell, 2012/04/17, Volume 21, Issue 4, p.547-62, (2012)
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INRICH: Interval-based Enrichment Analysis for Genome Wide Association Studies. Bioinformatics (Oxford, England), 2012/04/17, (2012)
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RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities. Proceedings of the National Academy of Sciences of the United States of America, 2012/04/17, Volume 109, Issue 16, p.6217-22, (2012)
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pIRS: Profile based Illumina pair-end Reads Simulator. Bioinformatics (Oxford, England), 2012/04/15, (2012)
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Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Molecular & cellular proteomics : MCP, 2012/04/14, (2012)
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Fast and accurate inference of local ancestry in Latino populations. Bioinformatics (Oxford, England), 2012/04/11, (2012)
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Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection. American journal of human genetics, 2012/04/06, Volume 90, Issue 4, p.720-6, (2012)
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The genomic basis of adaptive evolution in threespine sticklebacks. Nature, 2012/04/04, Volume 484, Issue 7392, p.55-61, (2012)
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature, 2012/03/28, Volume 483, Issue 7391, p.603-7, (2012)
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A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature, 2012/03/28, Volume 484, Issue 7394, p.339-44, (2012)
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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nature genetics, 2012/03/25, (2012)
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Rapid, field-deployable method for genotyping and discovery of drug-resistance single nucleotide polymorphisms in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2012/03/19, (2012)
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Genetics of human cardiovascular disease. Cell, 2012/03/16, Volume 148, Issue 6, p.1242-57, (2012)
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Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor. ACS medicinal chemistry letters, 2012/03/08, Volume 3, Issue 3, p.232-237, (2012)
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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nature protocols, 2012/03/01, Volume 7, Issue 3, p.562-78, (2012)
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Genome-wide association studies of schizophrenia: does bigger lead to better results? Current opinion in psychiatry, 2012/03/01, Volume 25, Issue 2, p.76-82, (2012)
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Highly sensitive and specific detection of rare variants in mixed viral populations from massively parallel sequence data. PLoS computational biology, 2012/03/01, Volume 8, Issue 3, p.e1002417, (2012)
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Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. Nature biotechnology, 2012/02/26, Volume 30, Issue 3, p.271-7, (2012)
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Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.3065-70, (2012)
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Abstract
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.2860-5, (2012)
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Development of small-molecule probes that selectively kill cells induced to express mutant RAS. Bioorganic & medicinal chemistry letters, 2012/02/15, Volume 22, Issue 4, p.1822-6, (2012)
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Abstract
Modular regulatory principles of large non-coding RNAs. Nature, 2012/02/15, Volume 482, Issue 7385, p.339-46, (2012)
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Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization. ACS combinatorial science, 2012/02/13, Volume 14, Issue 2, p.89-96, (2012)
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Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria. ACS medicinal chemistry letters, 2012/02/09, Volume 3, Issue 2, p.112-117, (2012)
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RNA folding with soft constraints: reconciliation of probing data and thermodynamic secondary structure prediction. Nucleic acids research, 2012/01/28, (2012)
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The mystery of missing heritability: Genetic interactions create phantom heritability. Proceedings of the National Academy of Sciences of the United States of America, 2012/01/24, Volume 109, Issue 4, p.1193-8, (2012)
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Human evolutionary genomics: ethical and interpretive issues. Trends in genetics : TIG, 2012/01/20, (2012)
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Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology, 2012/01/18, (2012)
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High-throughput real-time PCR for detection of gene-expression levels. Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 486, p.167-75, (2012)
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Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC. Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 803, p.129-40, (2012)
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Stable isotope labeling by amino acids in cell culture for quantitative proteomics. Methods in molecular biology (Clifton, N.J.), 2012/01/06, Volume 359, p.37-52, (2012)
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A Chemical Screen Probing the Relationship between Mitochondrial Content and Cell Size. PloS one, 2012/01/01, Volume 7, Issue 3, p.e33755, (2012)
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GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity. PloS one, 2012/01/01, Volume 7, Issue 1, p.e28808, (2012)
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High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections. Journal of virology, 2012/01/01, Volume 86, Issue 2, p.835-43, (2012)
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Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region. PloS one, 2012/01/01, Volume 7, Issue 2, p.e26038, (2012)
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Points of view: Data exploration. Nature methods, 2012/01/01, Volume 9, Issue 1, p.5, (2012)
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iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics. Molecular & cellular proteomics : MCP, 2011/12/30, (2011)
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Abstract
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. The New England journal of medicine, 2011/12/29, Volume 365, Issue 26, p.2497-506, (2011)
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Unbiased binding assays for discovering small-molecule probes and drugs. Bioorganic & medicinal chemistry, 2011/12/24, (2011)
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Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell, 2011/12/23, Volume 147, Issue 7, p.1628-39, (2011)
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Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011)
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Abstract
The microbial opsin family of optogenetic tools. Cell, 2011/12/23, Volume 147, Issue 7, p.1446-57, (2011)
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Abstract
Inter-laboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma. Molecular & cellular proteomics : MCP, 2011/12/22, (2011)
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Abstract
Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity. Science translational medicine, 2011/12/21, Volume 3, Issue 114, p.114ra128, (2011)
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Abstract
Detecting novel associations in large data sets. Science (New York, N.Y.), 2011/12/16, Volume 334, Issue 6062, p.1518-24, (2011)
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Abstract
Experimental and analytical tools for studying the human microbiome. Nature reviews. Genetics, 2011/12/16, Volume 13, Issue 1, p.47-58, (2011)
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Abstract
Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed Therapies. Cancer research, 2011/12/15, Volume 71, Issue 24, p.7587-96, (2011)
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Abstract
Genome-wide Association of Copy-Number Variation Reveals an Association between Short Stature and the Presence of Low-Frequency Genomic Deletions. American journal of human genetics, 2011/12/09, Volume 89, Issue 6, p.751-9, (2011)
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Abstract
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Molecular & cellular proteomics : MCP, 2011/12/09, (2011)
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Abstract
The changing face of genomics. Genome biology, 2011/12/08, Volume 5, Issue 5, p.324, (2011)
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Chemical genomics: probing protein function using small molecules. American journal of pharmacogenomics : genomics-related research in drug development and clinical practice, 2011/12/08, Volume 4, Issue 5, p.313-20, (2011)
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Abstract
Chromosome substitution strains: a new way to study genetically complex traits. Methods in molecular medicine, 2011/12/08, Volume 128, p.153-72, (2011)
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Disease gene discovery through integrative genomics. Annual review of genomics and human genetics, 2011/12/08, Volume 6, p.381-406, (2011)
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Global nucleosome occupancy in yeast. Genome biology, 2011/12/08, Volume 5, Issue 9, p.R62, (2011)
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Large-scale discovery and validation of functional elements in the human genome. Genome biology, 2011/12/08, Volume 6, Issue 3, p.312, (2011)
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A method for high-throughput gene expression signature analysis. Genome biology, 2011/12/08, Volume 7, Issue 7, p.R61, (2011)
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Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery. Journal of computational biology : a journal of computational molecular cell biology, 2011/12/08, Volume 11, Issue 2-3, p.319-55, (2011)
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Abstract
Progress towards identifying inflammatory bowel disease susceptibility genes. Novartis Foundation symposium, 2011/12/08, Volume 263, p.3-11; discussion 11-6, 211-8, (2011)
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Abstract
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic acids research, 2011/12/08, Volume 33, Issue 18, p.5868-77, (2011)
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Transferability of tag SNPs to capture common genetic variation in DNA repair genes across multiple populations. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2011/12/08, p.478-86, (2011)
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Abstract
The use of chromatin immunoprecipitation assays in genome-wide analyses of histone modifications. Methods in enzymology, 2011/12/08, Volume 376, p.349-60, (2011)
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What makes us human? Genome biology, 2011/12/08, Volume 5, Issue 8, p.238, (2011)
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Abstract
A Human Islet Cell Culture System for High-Throughput Screening. Journal of biomolecular screening, 2011/12/07, (2011)
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Abstract
Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers. Cancer discovery, 2011/12/01, Volume 1, Issue 7, p.608-25, (2011)
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Abstract
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Annals of neurology, 2011/12/01, Volume 70, Issue 6, p.897-912, (2011)
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Abstract
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types. PLoS genetics, 2011/12/01, Volume 7, Issue 12, p.e1002389, (2011)
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Abstract
Identification of small-molecule inhibitors of Trypansoma cruzi replication. Bioorganic & medicinal chemistry letters, 2011/12/01, Volume 21, Issue 23, p.7197-200, (2011)
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Abstract
A phylogenetic analysis using full-length viral genomes of South American dengue serotype 3 in consecutive Venezuelan outbreaks reveals a novel NS5 mutation. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2011/12/01, Volume 11, Issue 8, p.2011-9, (2011)
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Abstract
Visualization of parameter space for image analysis. IEEE transactions on visualization and computer graphics, 2011/12/01, Volume 17, Issue 12, p.2402-11, (2011)
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What can genetic studies of left ventricular mass tell us? Circulation. Cardiovascular genetics, 2011/12/01, Volume 4, Issue 6, p.581-4, (2011)
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Genetic Defect in CYP24A1, the Vitamin D 24-Hydroxylase Gene, in a Patient with Severe Infantile Hypercalcemia. The Journal of clinical endocrinology and metabolism, 2011/11/23, (2011)
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Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmo Diet and Cancer Study. The Journal of clinical endocrinology and metabolism, 2011/11/23, (2011)
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Abstract
GenomeView: a next-generation genome browser. Nucleic acids research, 2011/11/18, (2011)
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Abstract
Strategies to discover regulatory circuits of the mammalian immune system. Nature reviews. Immunology, 2011/11/18, Volume 11, Issue 12, p.873-80, (2011)
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Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development. Neuron, 2011/11/17, Volume 72, Issue 4, p.545-58, (2011)
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Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell, 2011/11/11, Volume 147, Issue 4, p.853-67, (2011)
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Abstract
RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/11/07, (2011)
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Abstract
Comprehensive proteomic study identifies serpin and cystatin antiproteases as novel correlates of HIV-1 resistance in the cervicovaginal mucosa of female sex workers. Journal of proteome research, 2011/11/04, Volume 10, Issue 11, p.5139-49, (2011)
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Abstract
Guiding DNA methylation. Cell stem cell, 2011/11/04, Volume 9, Issue 5, p.388-90, (2011)
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A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiology of aging, 2011/11/03, (2011)
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Abstract
Synaptic Deficits Are Rescued in the p25/Cdk5 Model of Neurodegeneration by the Reduction of β-Secretase (BACE1). The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011/11/02, Volume 31, Issue 44, p.15751-6, (2011)
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Abstract
Unfolding neurodevelopmental disorders: found in translation. Nature medicine, 2011/11/02, Volume 17, Issue 11, p.1352-3, (2011)
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Distribution Pattern of Plasmodium falciparum Chloroquine Transporter (pfcrt) Gene Haplotypes in Sri Lanka 1996-2006. The American journal of tropical medicine and hygiene, 2011/11/01, Volume 85, Issue 5, p.811-4, (2011)
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Abstract
Evolutionary divergence of intrinsic and trans-regulated nucleosome positioning sequences reveals plastic rules for chromatin organization. Genome research, 2011/11/01, Volume 21, Issue 11, p.1851-62, (2011)
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Abstract
Master Data Management: Getting your House in Order. Combinatorial chemistry & high throughput screening, 2011/11/01, Volume 14, Issue 9, p.749-56, (2011)
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