News from the Broad

The Broad Institute is committed to open sharing not only of its scientific data and tools, but also information and news about our progress towards achieving our mission. Below are just a few highlights from the Broad scientific community.
  • GINA, genetic discrimination, and genomic medicine

    February 4th, 2015

    In a New England Journal of Medicine perspective piece, Broad associate member Robert Green and co-authors examine the legacy of the 2008 Genetic Information Nondiscrimination Act (GINA). They note that, while few cases of genetic discrimination have ever been documented, pervasive fears persist about how personal genomic data may be used. This fear, they argue, may be hindering participation in genomic research. A story on their perspective piece can also be found on the Harvard Medical School website.

  • TCGA releases comprehensive genomic characterization of head and neck squamous cell carcinomas

    February 3rd, 2015

    Head and neck squamous cell carcinomas (HNSCCs) affect over 600,000 people annually around the world, many attributable to smoking or human papillomavirus infection. In order to understand the somatic gene mutations and copy number alterations present in these cancers, Broad researchers Andrew Cherniack, Peter Hammerman, Juok Cho, and colleagues as part of The Cancer Genome Atlas Network, profiled 279 HNSCCs. The studies, published in Nature, identified a number of shared and unique sequence alterations that could be further investigated with the goal of preventing and treating these cancers.

  • Variety show

    January 31st, 2015
    New techniques reveal “extreme” gene copy range
    Read Full Story
  • A new tool to DEPICT and predict

    January 29th, 2015

    Finding the causal genes at disease- and trait-associated loci is key to revealing biological insights from genome-wide association studies.

  • Broad, Harvard researchers unveil DeCoN, a new resource for neuron transcriptome data

    January 26th, 2015

    Recently in the journal Neuron, researchers reported on a new, high-throughput experimental method that, combined with massively parallel RNA sequencing and robust systems-level analyses, was used to characterize the transcriptome of three neuron populations in the neocortex. The team, which was led by researchers from the Broad Institute and Harvard University’s Department of Stem Cell and Regenerative Biology, have made this transcriptome data available in an intuitive, web-based resource called DeCoN.