MCL1 (green) and BCL-xL (gold) are anti-cell death proteins. Researchers identified high BCL-xL expression as a primary resistance mechanism to MCL1 inhibtion. Image from Wei et al. Volume 21, Issue 4, courtesy of Lauren Solomon, Broad Communications
Threespine sticklebacksImage courtesy Wikipedia
Image by Broad Communications, courtesy of iStockPhoto.
The Cancer Cell Line Encyclopedia is a public resource that integrates cancer genome data with predictors of drug response.Image courtesy of Sigrid Knemeyer, Broad Communications